Acute heart failure in rabbits by avocado leaf poisoning

The aim of this paper was to report an outbreak of avocado poisoning in rabbits in Salta, Argentina. Fourteen rabbits died of congestive heart failure within 30 h of ingesting fresh avocado leaves from pruned trees. They showed clinical signs of respiratory and cardiac distress. Full necropsies of...

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Autores principales: Aguirre, Laura S., Sandoval, Gabriela V., Medina, Diego M., Martínez, Olga Gladys, Micheloud, Juan Francisco
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: Elsevier 2019
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/5413
https://www.sciencedirect.com/science/article/pii/S0041010119301096?via%3Dihub
https://doi.org/10.1016/j.toxicon.2019.03.024
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author Aguirre, Laura S.
Sandoval, Gabriela V.
Medina, Diego M.
Martínez, Olga Gladys
Micheloud, Juan Francisco
author_browse Aguirre, Laura S.
Martínez, Olga Gladys
Medina, Diego M.
Micheloud, Juan Francisco
Sandoval, Gabriela V.
author_facet Aguirre, Laura S.
Sandoval, Gabriela V.
Medina, Diego M.
Martínez, Olga Gladys
Micheloud, Juan Francisco
author_sort Aguirre, Laura S.
collection INTA Digital
description The aim of this paper was to report an outbreak of avocado poisoning in rabbits in Salta, Argentina. Fourteen rabbits died of congestive heart failure within 30 h of ingesting fresh avocado leaves from pruned trees. They showed clinical signs of respiratory and cardiac distress. Full necropsies of four rabbits were performed and samples were collected for histopathology. The gross pathological observation included pleural and pericardial effusion, pulmonary oedema, slight ascites; the hearts appeared flabby and markedly pale. In addition, the stomach content consisted mostly of green feed with large amounts of avocado leaves. Epidermal fragments of Persea americana were identified by microhistological analysis of gastric content to get most efficiently to a correct diagnosis. Histopathological examination revealed degeneration and necrosis of myocytes and a mononuclear cellular infiltration mainly involving the myocardium and, to a lesser extent, the liver, lung and kidneys. Our observations indicate that avocado leaves should be avoided in the green diet of rabbits.
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institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
language Inglés
publishDate 2019
publishDateRange 2019
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publisher Elsevier
publisherStr Elsevier
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spelling INTA54132019-07-02T15:02:05Z Acute heart failure in rabbits by avocado leaf poisoning Aguirre, Laura S. Sandoval, Gabriela V. Medina, Diego M. Martínez, Olga Gladys Micheloud, Juan Francisco Enfermedades Cardiovasculares Conejo (Oryctolagus) Persea Americana Envenenamiento Miocardiopatía Aguacate Cardiovascular Diseases Rabbits Poisoning Cardiomyopathy Avocados Insuficiencia Cardíaca Palta The aim of this paper was to report an outbreak of avocado poisoning in rabbits in Salta, Argentina. Fourteen rabbits died of congestive heart failure within 30 h of ingesting fresh avocado leaves from pruned trees. They showed clinical signs of respiratory and cardiac distress. Full necropsies of four rabbits were performed and samples were collected for histopathology. The gross pathological observation included pleural and pericardial effusion, pulmonary oedema, slight ascites; the hearts appeared flabby and markedly pale. In addition, the stomach content consisted mostly of green feed with large amounts of avocado leaves. Epidermal fragments of Persea americana were identified by microhistological analysis of gastric content to get most efficiently to a correct diagnosis. Histopathological examination revealed degeneration and necrosis of myocytes and a mononuclear cellular infiltration mainly involving the myocardium and, to a lesser extent, the liver, lung and kidneys. Our observations indicate that avocado leaves should be avoided in the green diet of rabbits. EEA Salta Fil: Aguirre, Laura S. Universidad Católica de Salta. Facultad de Ciencias Agrarias y Veterinarias; Argentina Fil: Sandoval, Gabriela V. Universidad Católica de Salta. Facultad de Ciencias Agrarias y Veterinarias; Argentina Fil: Medina, Diego M. Universidad Católica de Salta. Facultad de Ciencias Agrarias y Veterinarias; Argentina Fil: Martínez, Olga Gladys. Universidad Nacional de Salta. Cátedra de Diversidad de las Plantas; Argentina Fil: Micheloud, Juan Francisco. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación Animal Chaco Semiarido. Grupo de Patología, Epidemiología e Investigación Diagnóstica-Área de Sanidad Animal; Argentina. Universidad Católica de Salta. Facultad de Ciencias Veterinarias. Cátedra de Patología General y Especial; Argentina. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Salta; Argentina 2019-07-02T14:54:19Z 2019-07-02T14:54:19Z 2019 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/5413 https://www.sciencedirect.com/science/article/pii/S0041010119301096?via%3Dihub 0041-0101 https://doi.org/10.1016/j.toxicon.2019.03.024 eng info:eu-repo/semantics/restrictedAccess application/pdf Elsevier Toxicon 164 :16-19. (June 2019)
spellingShingle Enfermedades Cardiovasculares
Conejo (Oryctolagus)
Persea Americana
Envenenamiento
Miocardiopatía
Aguacate
Cardiovascular Diseases
Rabbits
Poisoning
Cardiomyopathy
Avocados
Insuficiencia Cardíaca
Palta
Aguirre, Laura S.
Sandoval, Gabriela V.
Medina, Diego M.
Martínez, Olga Gladys
Micheloud, Juan Francisco
Acute heart failure in rabbits by avocado leaf poisoning
title Acute heart failure in rabbits by avocado leaf poisoning
title_full Acute heart failure in rabbits by avocado leaf poisoning
title_fullStr Acute heart failure in rabbits by avocado leaf poisoning
title_full_unstemmed Acute heart failure in rabbits by avocado leaf poisoning
title_short Acute heart failure in rabbits by avocado leaf poisoning
title_sort acute heart failure in rabbits by avocado leaf poisoning
topic Enfermedades Cardiovasculares
Conejo (Oryctolagus)
Persea Americana
Envenenamiento
Miocardiopatía
Aguacate
Cardiovascular Diseases
Rabbits
Poisoning
Cardiomyopathy
Avocados
Insuficiencia Cardíaca
Palta
url http://hdl.handle.net/20.500.12123/5413
https://www.sciencedirect.com/science/article/pii/S0041010119301096?via%3Dihub
https://doi.org/10.1016/j.toxicon.2019.03.024
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