Salicylic acid is involved in the Nb-mediated defense responses to Potato virus X in Solanum tuberosum

To evaluate the role of salicylic acid (SA) in Nb-mediated hypersensitive resistance to Potato virus X (PVX) avirulent strain ROTH1 in Solanum tuberosum, we have constructed SA-deficient transgenic potato plant lines by overexpressing the bacterial enzyme salicylate hydroxylase (NahG), which degrade...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanchez, Gerardo, Gerhardt, Nadia, Siciliano, Florencia, Vojnov, Adrián, Malcuit, Isabelle, Marano, María Rosa
Formato: Artículo
Lenguaje:Inglés
Publicado: 2019
Materias:
Acceso en línea:https://www.apsnet.org/publications/mpmi/2010/April/Pages/23_4_394.aspx
http://hdl.handle.net/20.500.12123/5317
http://dx.doi.org/10.1094/MPMI-23-4-0394
_version_ 1855483600634380288
author Sanchez, Gerardo
Gerhardt, Nadia
Siciliano, Florencia
Vojnov, Adrián
Malcuit, Isabelle
Marano, María Rosa
author_browse Gerhardt, Nadia
Malcuit, Isabelle
Marano, María Rosa
Sanchez, Gerardo
Siciliano, Florencia
Vojnov, Adrián
author_facet Sanchez, Gerardo
Gerhardt, Nadia
Siciliano, Florencia
Vojnov, Adrián
Malcuit, Isabelle
Marano, María Rosa
author_sort Sanchez, Gerardo
collection INTA Digital
description To evaluate the role of salicylic acid (SA) in Nb-mediated hypersensitive resistance to Potato virus X (PVX) avirulent strain ROTH1 in Solanum tuberosum, we have constructed SA-deficient transgenic potato plant lines by overexpressing the bacterial enzyme salicylate hydroxylase (NahG), which degrades SA. Evaluation of these transgenic lines revealed hydrogen peroxide accumulation and spontaneous lesion formation in an age- and light-dependent manner. In concordance, NahG potato plants were more sensitive to treatment with methyl viologen, a reactive oxygen species--generating compound. In addition, when challenged with PVX ROTH1, NahG transgenic lines showed a decreased disease-resistance response to infection and were unable to induce systemic acquired resistance. However, the avirulent viral effector, the PVX 25-kDa protein, does induce expression of the pathogenesis-related gene PR-1a in NahG potato plants. Taken together, our data indicate that SA is involved in local and systemic defense responses mediated by the Nb gene in Solanum tuberosum. This is the first report to show that basal levels of SA correlate with hypersensitive resistance to PVX.
format Artículo
id INTA5317
institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
language Inglés
publishDate 2019
publishDateRange 2019
publishDateSort 2019
record_format dspace
spelling INTA53172019-06-14T11:37:38Z Salicylic acid is involved in the Nb-mediated defense responses to Potato virus X in Solanum tuberosum Sanchez, Gerardo Gerhardt, Nadia Siciliano, Florencia Vojnov, Adrián Malcuit, Isabelle Marano, María Rosa Papa Solanum tuberosum Ácido Salicílico Potatoes Potato Virus A Salicylic Acid To evaluate the role of salicylic acid (SA) in Nb-mediated hypersensitive resistance to Potato virus X (PVX) avirulent strain ROTH1 in Solanum tuberosum, we have constructed SA-deficient transgenic potato plant lines by overexpressing the bacterial enzyme salicylate hydroxylase (NahG), which degrades SA. Evaluation of these transgenic lines revealed hydrogen peroxide accumulation and spontaneous lesion formation in an age- and light-dependent manner. In concordance, NahG potato plants were more sensitive to treatment with methyl viologen, a reactive oxygen species--generating compound. In addition, when challenged with PVX ROTH1, NahG transgenic lines showed a decreased disease-resistance response to infection and were unable to induce systemic acquired resistance. However, the avirulent viral effector, the PVX 25-kDa protein, does induce expression of the pathogenesis-related gene PR-1a in NahG potato plants. Taken together, our data indicate that SA is involved in local and systemic defense responses mediated by the Nb gene in Solanum tuberosum. This is the first report to show that basal levels of SA correlate with hypersensitive resistance to PVX. EEA San Pedro Fil: Sánchez, Gerardo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria San Pedro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología Molecular y Celular de Rosario; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina. Fil: Gerhardt, Nadia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología Molecular y Celular de Rosario; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina. Fil: Siciliano, Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología Molecular y Celular de Rosario; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina Fil: Vojnov, Adrián. Fundación Pablo Cassará; Argentina Fil: Malcuit, Isabelle. Algentech Limited; Reino Unido. Institute of Food Research; Reino Unido Fil: Marano, María Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología Molecular y Celular de Rosario; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina 2019-06-14T11:31:43Z 2019-06-14T11:31:43Z 2010 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://www.apsnet.org/publications/mpmi/2010/April/Pages/23_4_394.aspx http://hdl.handle.net/20.500.12123/5317 0894-0282 1943-7706 http://dx.doi.org/10.1094/MPMI-23-4-0394 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Molecular Plant-Microbe Interactions 23 (4) : 394-405. (2010)
spellingShingle Papa
Solanum tuberosum
Ácido Salicílico
Potatoes
Potato Virus A
Salicylic Acid
Sanchez, Gerardo
Gerhardt, Nadia
Siciliano, Florencia
Vojnov, Adrián
Malcuit, Isabelle
Marano, María Rosa
Salicylic acid is involved in the Nb-mediated defense responses to Potato virus X in Solanum tuberosum
title Salicylic acid is involved in the Nb-mediated defense responses to Potato virus X in Solanum tuberosum
title_full Salicylic acid is involved in the Nb-mediated defense responses to Potato virus X in Solanum tuberosum
title_fullStr Salicylic acid is involved in the Nb-mediated defense responses to Potato virus X in Solanum tuberosum
title_full_unstemmed Salicylic acid is involved in the Nb-mediated defense responses to Potato virus X in Solanum tuberosum
title_short Salicylic acid is involved in the Nb-mediated defense responses to Potato virus X in Solanum tuberosum
title_sort salicylic acid is involved in the nb mediated defense responses to potato virus x in solanum tuberosum
topic Papa
Solanum tuberosum
Ácido Salicílico
Potatoes
Potato Virus A
Salicylic Acid
url https://www.apsnet.org/publications/mpmi/2010/April/Pages/23_4_394.aspx
http://hdl.handle.net/20.500.12123/5317
http://dx.doi.org/10.1094/MPMI-23-4-0394
work_keys_str_mv AT sanchezgerardo salicylicacidisinvolvedinthenbmediateddefenseresponsestopotatovirusxinsolanumtuberosum
AT gerhardtnadia salicylicacidisinvolvedinthenbmediateddefenseresponsestopotatovirusxinsolanumtuberosum
AT sicilianoflorencia salicylicacidisinvolvedinthenbmediateddefenseresponsestopotatovirusxinsolanumtuberosum
AT vojnovadrian salicylicacidisinvolvedinthenbmediateddefenseresponsestopotatovirusxinsolanumtuberosum
AT malcuitisabelle salicylicacidisinvolvedinthenbmediateddefenseresponsestopotatovirusxinsolanumtuberosum
AT maranomariarosa salicylicacidisinvolvedinthenbmediateddefenseresponsestopotatovirusxinsolanumtuberosum