Risk factors for shiga toxin-producing Escherichia coli-associated human diseases

We have reviewed the risk factors for the occurrence of Shiga toxin-producing Escherichia coli (STEC)-associated human diseases. The analysis of STEC surveillance data and trends shows differences in frequency and severity of the illnesses across countries, whereas the economic and social costs for...

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Main Authors: Rivas, Marta, Chinen, Isabel, Miliwebsky, Elizabeth, Masana, Marcelo Oscar
Format: info:ar-repo/semantics/artículo
Language:Inglés
Published: American Society for Microbiology 2019
Subjects:
Online Access:http://hdl.handle.net/20.500.12123/4774
http://www.asmscience.org/content/journal/microbiolspec/10.1128/microbiolspec.EHEC-0002-2013
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author Rivas, Marta
Chinen, Isabel
Miliwebsky, Elizabeth
Masana, Marcelo Oscar
author_browse Chinen, Isabel
Masana, Marcelo Oscar
Miliwebsky, Elizabeth
Rivas, Marta
author_facet Rivas, Marta
Chinen, Isabel
Miliwebsky, Elizabeth
Masana, Marcelo Oscar
author_sort Rivas, Marta
collection INTA Digital
description We have reviewed the risk factors for the occurrence of Shiga toxin-producing Escherichia coli (STEC)-associated human diseases. The analysis of STEC surveillance data and trends shows differences in frequency and severity of the illnesses across countries, whereas the economic and social costs for the affected families, the community, and the health system are better estimated in developed countries. The occurrence of STEC infections is determined by the interaction of the pathogen, the reservoirs, and the biological, cultural, and behavioral aspects of the host. The main risk factors identified in earlier case-control and population-based studies were dietary behaviors and beef consumption. However, in recent years, other risky exposures have also emerged, like the consumption of raw vegetables and sprouts, working or camping in rural areas, visiting farms, and person-to-person transmission. Epidemiological changes have also been determined by the intensification of cattle production, the increase in centralized food production and distribution, and the growth in the volume of international trade of foods. The main lessons learned from recent large outbreaks are knowledge of virulence determinants of new pathogenic strains, recognition of new vehicles of infection, development of new methodologies for detecting STEC in foods and humans, improvement in food regulations and hygiene guidelines, new therapeutic approaches in the treatment of infected patients, establishment of continuous educational programs for food consumers, and enhanced cooperation and teamwork of regional and international networks.
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institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
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spelling INTA47742019-03-28T15:55:19Z Risk factors for shiga toxin-producing Escherichia coli-associated human diseases Rivas, Marta Chinen, Isabel Miliwebsky, Elizabeth Masana, Marcelo Oscar Risk Factors Human Diseases Toxins Factores de Riesgo Escherichia Coli Enfermedades Humanas Toxinas Shiga Toxin We have reviewed the risk factors for the occurrence of Shiga toxin-producing Escherichia coli (STEC)-associated human diseases. The analysis of STEC surveillance data and trends shows differences in frequency and severity of the illnesses across countries, whereas the economic and social costs for the affected families, the community, and the health system are better estimated in developed countries. The occurrence of STEC infections is determined by the interaction of the pathogen, the reservoirs, and the biological, cultural, and behavioral aspects of the host. The main risk factors identified in earlier case-control and population-based studies were dietary behaviors and beef consumption. However, in recent years, other risky exposures have also emerged, like the consumption of raw vegetables and sprouts, working or camping in rural areas, visiting farms, and person-to-person transmission. Epidemiological changes have also been determined by the intensification of cattle production, the increase in centralized food production and distribution, and the growth in the volume of international trade of foods. The main lessons learned from recent large outbreaks are knowledge of virulence determinants of new pathogenic strains, recognition of new vehicles of infection, development of new methodologies for detecting STEC in foods and humans, improvement in food regulations and hygiene guidelines, new therapeutic approaches in the treatment of infected patients, establishment of continuous educational programs for food consumers, and enhanced cooperation and teamwork of regional and international networks. Instituto de Tecnología de los Alimentos Fil: Chinen, Isabel. Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán”. Instituto Nacional de Enfermedades Infecciosas; Argentina Fil: Rivas, Marta. Argentina. Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán”. Instituto Nacional de Enfermedades Infecciosas; Argentina Fil: Miliwebsky, Elizabeth. Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán”. Instituto Nacional de Enfermedades Infecciosas; Argentina Fil: Masana, Marcelo Oscar. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto Tecnología de Alimentos; Argentina 2019-03-28T15:50:32Z 2019-03-28T15:50:32Z 2014 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/4774 http://www.asmscience.org/content/journal/microbiolspec/10.1128/microbiolspec.EHEC-0002-2013 2165-0497 10.1128/microbiolspec.EHEC-0002-2013 eng info:eu-repo/semantics/restrictedAccess application/pdf American Society for Microbiology Microbiology spectrum 2 (5) : EHEC-0002-2013. (12 septiembre 2014)
spellingShingle Risk Factors
Human Diseases
Toxins
Factores de Riesgo
Escherichia Coli
Enfermedades Humanas
Toxinas
Shiga Toxin
Rivas, Marta
Chinen, Isabel
Miliwebsky, Elizabeth
Masana, Marcelo Oscar
Risk factors for shiga toxin-producing Escherichia coli-associated human diseases
title Risk factors for shiga toxin-producing Escherichia coli-associated human diseases
title_full Risk factors for shiga toxin-producing Escherichia coli-associated human diseases
title_fullStr Risk factors for shiga toxin-producing Escherichia coli-associated human diseases
title_full_unstemmed Risk factors for shiga toxin-producing Escherichia coli-associated human diseases
title_short Risk factors for shiga toxin-producing Escherichia coli-associated human diseases
title_sort risk factors for shiga toxin producing escherichia coli associated human diseases
topic Risk Factors
Human Diseases
Toxins
Factores de Riesgo
Escherichia Coli
Enfermedades Humanas
Toxinas
Shiga Toxin
url http://hdl.handle.net/20.500.12123/4774
http://www.asmscience.org/content/journal/microbiolspec/10.1128/microbiolspec.EHEC-0002-2013
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