Babesia life cycle – When phylogeny meets biology
Although Babesia represents an important worldwide veterinary threat and an emerging risk to humans, this parasite has been poorly studied as compared to Plasmodium, its malaria-causing relative. In fact, Babesia employs highly specific survival strategies during its intraerythrocytic development an...
| Main Authors: | , , , |
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| Format: | info:ar-repo/semantics/reseña artículo |
| Language: | Inglés |
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Elsevier
2019
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.12123/4744 https://www.sciencedirect.com/science/article/pii/S1471492219300200?via%3Dihub https://doi.org/10.1016/j.pt.2019.01.007 |
| _version_ | 1855035377070374912 |
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| author | Jalovecka, Marie Sojka, Daniel Ascencio, Mariano E. Schnittger, Leonhard |
| author_browse | Ascencio, Mariano E. Jalovecka, Marie Schnittger, Leonhard Sojka, Daniel |
| author_facet | Jalovecka, Marie Sojka, Daniel Ascencio, Mariano E. Schnittger, Leonhard |
| author_sort | Jalovecka, Marie |
| collection | INTA Digital |
| description | Although Babesia represents an important worldwide veterinary threat and an emerging risk to humans, this parasite has been poorly studied as compared to Plasmodium, its malaria-causing relative. In fact, Babesia employs highly specific survival strategies during its intraerythrocytic development and its intricate journey through the tick vector. This review introduces a substantially extended molecular phylogeny of the order Piroplasmida, challenging previous taxonomic classifications. The intriguing developmental proficiencies of Babesia are highlighted and compared with those of other haemoparasitic Apicomplexa. Molecular mechanisms associated with distinctive events in the Babesia life cycle are emphasized as potential targets for the development of Babesia-specific treatments. |
| format | info:ar-repo/semantics/reseña artículo |
| id | INTA4744 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2019 |
| publishDateRange | 2019 |
| publishDateSort | 2019 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | INTA47442019-03-26T15:40:47Z Babesia life cycle – When phylogeny meets biology Jalovecka, Marie Sojka, Daniel Ascencio, Mariano E. Schnittger, Leonhard Babesia Ciclo Vital Filogenia Biología Metastigmata Biología Molecular Life Cycle Phylogeny Biology Molecular Biology Although Babesia represents an important worldwide veterinary threat and an emerging risk to humans, this parasite has been poorly studied as compared to Plasmodium, its malaria-causing relative. In fact, Babesia employs highly specific survival strategies during its intraerythrocytic development and its intricate journey through the tick vector. This review introduces a substantially extended molecular phylogeny of the order Piroplasmida, challenging previous taxonomic classifications. The intriguing developmental proficiencies of Babesia are highlighted and compared with those of other haemoparasitic Apicomplexa. Molecular mechanisms associated with distinctive events in the Babesia life cycle are emphasized as potential targets for the development of Babesia-specific treatments. Instituto de Patobiología Fil: Jalovecka, Marie. Czech Academy of Sciences. Institute of Parasitology, Biology Centre; República Checa. University of South Bohemia. Faculty of Science; República Checa Fil: Sojka, Daniel. Czech Academy of Sciences. Institute of Parasitology, Biology Centre; República Checa Fil: Ascencio, Mariano E. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Schnittger, Leonhard. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina 2019-03-26T15:34:34Z 2019-03-26T15:34:34Z 2019-02-04 info:ar-repo/semantics/reseña artículo info:eu-repo/semantics/review info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/4744 https://www.sciencedirect.com/science/article/pii/S1471492219300200?via%3Dihub 1471-4922 https://doi.org/10.1016/j.pt.2019.01.007 eng info:eu-repo/semantics/restrictedAccess application/pdf Elsevier Trends in parasitology. (4 February 2019) |
| spellingShingle | Babesia Ciclo Vital Filogenia Biología Metastigmata Biología Molecular Life Cycle Phylogeny Biology Molecular Biology Jalovecka, Marie Sojka, Daniel Ascencio, Mariano E. Schnittger, Leonhard Babesia life cycle – When phylogeny meets biology |
| title | Babesia life cycle – When phylogeny meets biology |
| title_full | Babesia life cycle – When phylogeny meets biology |
| title_fullStr | Babesia life cycle – When phylogeny meets biology |
| title_full_unstemmed | Babesia life cycle – When phylogeny meets biology |
| title_short | Babesia life cycle – When phylogeny meets biology |
| title_sort | babesia life cycle when phylogeny meets biology |
| topic | Babesia Ciclo Vital Filogenia Biología Metastigmata Biología Molecular Life Cycle Phylogeny Biology Molecular Biology |
| url | http://hdl.handle.net/20.500.12123/4744 https://www.sciencedirect.com/science/article/pii/S1471492219300200?via%3Dihub https://doi.org/10.1016/j.pt.2019.01.007 |
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