Human brucellosis and adverse pregnancy outcomes
Purpose of Review Brucellosis is a neglected, zoonotic disease of nearly worldwide distribution. Despite brucellosis being recognized as a reproductive disease in animals, it has been historically known as a flu-like illness in humans with little or no significant role in maternal or newborn hea...
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| Format: | info:ar-repo/semantics/artículo |
| Language: | Inglés |
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Springer
2019
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| Online Access: | http://hdl.handle.net/20.500.12123/4498 https://link.springer.com/article/10.1007/s40475-016-0092-0#citeas https://doi.org/10.1007/s40475-016-0092-0 |
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| author | Arenas-Gamboa, Angela M. Rossetti, Carlos Alberto Chaki, Sankar P. Garcia-Gonzalez, Daniel G. Adams, Leslie G. Ficht, Thomas A. |
| author_browse | Adams, Leslie G. Arenas-Gamboa, Angela M. Chaki, Sankar P. Ficht, Thomas A. Garcia-Gonzalez, Daniel G. Rossetti, Carlos Alberto |
| author_facet | Arenas-Gamboa, Angela M. Rossetti, Carlos Alberto Chaki, Sankar P. Garcia-Gonzalez, Daniel G. Adams, Leslie G. Ficht, Thomas A. |
| author_sort | Arenas-Gamboa, Angela M. |
| collection | INTA Digital |
| description | Purpose of Review Brucellosis is a neglected, zoonotic disease
of nearly worldwide distribution. Despite brucellosis being
recognized as a reproductive disease in animals, it has
been historically known as a flu-like illness in humans with
little or no significant role in maternal or newborn health. This
review focuses on what is currently known relative to the
epidemiology of brucellosis in human pregnancy as well as
new insights of placental immunology.
Recent Findings New evidence suggests that maternal infection
poses a significant risk factor for adverse pregnancy outcomes
including increased risk for miscarriage during the first
and second trimester of gestation, preterm delivery, and vertical
transmission to the fetus. Adverse pregnancy outcomes
were not associated with any specific clinical sign. However,
prompt diagnosis and treatment significantly decreased the
risk of miscarriage or any other adverse effect.
Summary Brucellosis during pregnancy should be considered
a significant risk factor for adverse pregnancy outcomes in
humans. The identification of the mechanism behind bacterial
tropism should prove powerful for the development of new
countermeasures to prevent these detrimental effects.
Increased awareness concerning brucellosis in pregnant women,
its transmission, and prevention measures should be considered
as a pressing need. |
| format | info:ar-repo/semantics/artículo |
| id | INTA4498 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2019 |
| publishDateRange | 2019 |
| publishDateSort | 2019 |
| publisher | Springer |
| publisherStr | Springer |
| record_format | dspace |
| spelling | INTA44982019-02-26T17:17:27Z Human brucellosis and adverse pregnancy outcomes Arenas-Gamboa, Angela M. Rossetti, Carlos Alberto Chaki, Sankar P. Garcia-Gonzalez, Daniel G. Adams, Leslie G. Ficht, Thomas A. Human Diseases Abortion Zoonoses Pregnancy Enfermedades Humanas Brucellosis Aborto Zoonosis Placenta Gestación Purpose of Review Brucellosis is a neglected, zoonotic disease of nearly worldwide distribution. Despite brucellosis being recognized as a reproductive disease in animals, it has been historically known as a flu-like illness in humans with little or no significant role in maternal or newborn health. This review focuses on what is currently known relative to the epidemiology of brucellosis in human pregnancy as well as new insights of placental immunology. Recent Findings New evidence suggests that maternal infection poses a significant risk factor for adverse pregnancy outcomes including increased risk for miscarriage during the first and second trimester of gestation, preterm delivery, and vertical transmission to the fetus. Adverse pregnancy outcomes were not associated with any specific clinical sign. However, prompt diagnosis and treatment significantly decreased the risk of miscarriage or any other adverse effect. Summary Brucellosis during pregnancy should be considered a significant risk factor for adverse pregnancy outcomes in humans. The identification of the mechanism behind bacterial tropism should prove powerful for the development of new countermeasures to prevent these detrimental effects. Increased awareness concerning brucellosis in pregnant women, its transmission, and prevention measures should be considered as a pressing need. Instituto de Patobiología Fil: Arenas-Gamboa, Angela M. Texas A&M University. College of Veterinary Medicine & Biomedical Sciences. Department of Veterinary Pathobiology; Estados Unidos Fil: Rossetti, Carlos Alberto. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina Fil: Chaki, Sankar P. Texas A&M University. College of Veterinary Medicine & Biomedical Sciences. Department of Veterinary Pathobiology; Estados Unidos Fil: Garcia-Gonzalez, Daniel G. Texas A&M University. College of Veterinary Medicine & Biomedical Sciences. Department of Veterinary Pathobiology; Estados Unidos Fil: Adams, Leslie G. Texas A&M University. College of Veterinary Medicine & Biomedical Sciences. Department of Veterinary Pathobiology; Estados Unidos Fil: Ficht, Thomas A. Texas A&M University. College of Veterinary Medicine & Biomedical Sciences. Department of Veterinary Pathobiology; Estados Unidos 2019-02-26T17:08:39Z 2019-02-26T17:08:39Z 2016-12 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/4498 https://link.springer.com/article/10.1007/s40475-016-0092-0#citeas 2196-3045 (Online) https://doi.org/10.1007/s40475-016-0092-0 eng info:eu-repo/semantics/restrictedAccess application/pdf Springer Current tropical medicine reports 3 (4) : 164–172. (December 2016) |
| spellingShingle | Human Diseases Abortion Zoonoses Pregnancy Enfermedades Humanas Brucellosis Aborto Zoonosis Placenta Gestación Arenas-Gamboa, Angela M. Rossetti, Carlos Alberto Chaki, Sankar P. Garcia-Gonzalez, Daniel G. Adams, Leslie G. Ficht, Thomas A. Human brucellosis and adverse pregnancy outcomes |
| title | Human brucellosis and adverse pregnancy outcomes |
| title_full | Human brucellosis and adverse pregnancy outcomes |
| title_fullStr | Human brucellosis and adverse pregnancy outcomes |
| title_full_unstemmed | Human brucellosis and adverse pregnancy outcomes |
| title_short | Human brucellosis and adverse pregnancy outcomes |
| title_sort | human brucellosis and adverse pregnancy outcomes |
| topic | Human Diseases Abortion Zoonoses Pregnancy Enfermedades Humanas Brucellosis Aborto Zoonosis Placenta Gestación |
| url | http://hdl.handle.net/20.500.12123/4498 https://link.springer.com/article/10.1007/s40475-016-0092-0#citeas https://doi.org/10.1007/s40475-016-0092-0 |
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