Structure-based drug design for envelope protein E2 uncovers a new class of bovine viral diarrhea inhibitors that block virus entry

Antiviral targeting of virus envelope proteins is an effective strategy for therapeutic intervention of viral infections. Here, we took a computer-guided approach with the aim of identifying new antivirals against the envelope protein E2 of bovine viral diarrhea virus (BVDV). BVDV is an enveloped vi...

Full description

Bibliographic Details
Main Authors: Pascual, María José, Merwaiss, Fernando, Leal, Emilse Soledad, Quintana, Maria Eugenia, Capozzo, Alejandra Victoria, Cavasotto, Claudio Norberto, Bollini, Mariela, Alvarez, Diego Ezequiel
Format: Artículo
Language:Inglés
Published: Elsevier 2019
Subjects:
Online Access:http://hdl.handle.net/20.500.12123/4480
https://www.sciencedirect.com/science/article/pii/S0166354217305983?via%3Dihub#!
https://doi.org/10.1016/j.antiviral.2017.10.010

Similar Items: Structure-based drug design for envelope protein E2 uncovers a new class of bovine viral diarrhea inhibitors that block virus entry