Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, Argentina
Background: Bovine brucellosis (BB) is a zoonotic disease caused by Brucella abortus. BB is endemic in Argentina, where vaccination with Brucella abortus strain 19 is compulsory for 3-to-8 month-old heifers. The objectives of this study were to quantify the prevalence of BB and to identify factors...
| Autores principales: | , , , , , , , |
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| Formato: | info:ar-repo/semantics/artículo |
| Lenguaje: | Inglés |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12123/4475 https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-015-0535-1 https://doi.org/10.1186/s12917-015-0535-1 |
| _version_ | 1855035330167570432 |
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| author | Aznar, Maria Natalia Linares, Facundo José Cosentino, Bernardo Sago, Adrián Miguel La Sala, Luciano Francisco Leon, Eduardo Duffy, Sergio Perez, Andrés |
| author_browse | Aznar, Maria Natalia Cosentino, Bernardo Duffy, Sergio La Sala, Luciano Francisco Leon, Eduardo Linares, Facundo José Perez, Andrés Sago, Adrián Miguel |
| author_facet | Aznar, Maria Natalia Linares, Facundo José Cosentino, Bernardo Sago, Adrián Miguel La Sala, Luciano Francisco Leon, Eduardo Duffy, Sergio Perez, Andrés |
| author_sort | Aznar, Maria Natalia |
| collection | INTA Digital |
| description | Background:
Bovine brucellosis (BB) is a zoonotic disease caused by Brucella abortus. BB is endemic in Argentina, where vaccination with Brucella abortus strain 19 is compulsory for 3-to-8 month-old heifers. The objectives of this study were to quantify the prevalence of BB and to identify factors associated with its occurrence, along with the spatial distribution of the disease, in the provinces of La Pampa and San Luis. A two-stage random sampling design was used to sample 8,965 cows (3,513 in La Pampa and 5,452 in San Luis) from 451 farms (187 in La Pampa and 264 in San Luis).
Results:
Cow and herd prevalence were 1.8 % (95 % CI: 1.3–2.2; n = 157) and 19.7 % (95 % CI: 17.0–22.4; n = 89), respectively. Both cow-level and herd-level prevalence in La Pampa (2.4 and 26.0 %, respectively) were significantly higher than in San Luis (1.4 and 15.5 %, respectively). There were not differences between the proportions of reactive cattle compared to that obtained in a survey conducted in 2005. However, herd prevalence in La Pampa was significantly (P < 0.05) higher compared to that study. Disease was found to be spatially clustered in west La Pampa. The lower the bovine density and the calf/cow ratio, the higher odds of belonging to the cluster.
Conclusions:
The increase of farm prevalence in the last five years suggests that the disease is spreading and that control measures should be applied in the region.
The cluster of infected farms was located in the west region of La Pampa. There, farms have lower animal densities and smaller cow/calf indices compared to the rest of the province. Although western La Pampa has more infected herds, within-farm prevalence was not higher, which suggests that the control program has been relatively successful in controlling the disease at the farm level, and/or that low animal density inherently results in low disease prevalence. Our results provide baseline information on the epidemiology of BB and its potential pattern of transmission in Argentina, which will ultimately help to improve BB control programs in the country. |
| format | info:ar-repo/semantics/artículo |
| id | INTA4475 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2019 |
| publishDateRange | 2019 |
| publishDateSort | 2019 |
| publisher | BioMed Central |
| publisherStr | BioMed Central |
| record_format | dspace |
| spelling | INTA44752019-02-20T15:21:24Z Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, Argentina Aznar, Maria Natalia Linares, Facundo José Cosentino, Bernardo Sago, Adrián Miguel La Sala, Luciano Francisco Leon, Eduardo Duffy, Sergio Perez, Andrés Morbosidad Distribución Espacial Brucella Abortus Morbidity Spatial Distribution Prevalence Prevalencia de una Enfermedad Bovine Brucellosis Brucelosis Bovina San Luis La Pampa Background: Bovine brucellosis (BB) is a zoonotic disease caused by Brucella abortus. BB is endemic in Argentina, where vaccination with Brucella abortus strain 19 is compulsory for 3-to-8 month-old heifers. The objectives of this study were to quantify the prevalence of BB and to identify factors associated with its occurrence, along with the spatial distribution of the disease, in the provinces of La Pampa and San Luis. A two-stage random sampling design was used to sample 8,965 cows (3,513 in La Pampa and 5,452 in San Luis) from 451 farms (187 in La Pampa and 264 in San Luis). Results: Cow and herd prevalence were 1.8 % (95 % CI: 1.3–2.2; n = 157) and 19.7 % (95 % CI: 17.0–22.4; n = 89), respectively. Both cow-level and herd-level prevalence in La Pampa (2.4 and 26.0 %, respectively) were significantly higher than in San Luis (1.4 and 15.5 %, respectively). There were not differences between the proportions of reactive cattle compared to that obtained in a survey conducted in 2005. However, herd prevalence in La Pampa was significantly (P < 0.05) higher compared to that study. Disease was found to be spatially clustered in west La Pampa. The lower the bovine density and the calf/cow ratio, the higher odds of belonging to the cluster. Conclusions: The increase of farm prevalence in the last five years suggests that the disease is spreading and that control measures should be applied in the region. The cluster of infected farms was located in the west region of La Pampa. There, farms have lower animal densities and smaller cow/calf indices compared to the rest of the province. Although western La Pampa has more infected herds, within-farm prevalence was not higher, which suggests that the control program has been relatively successful in controlling the disease at the farm level, and/or that low animal density inherently results in low disease prevalence. Our results provide baseline information on the epidemiology of BB and its potential pattern of transmission in Argentina, which will ultimately help to improve BB control programs in the country. Instituto de Patobiología Fil: Aznar, Maria Natalia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología. Area de Patología, Epidemiología y Medicina Preventiva; Argentina. University of Liege. Faculty of Veterinary Medicine. Department of Infectious and Parasitic Diseases. Research Unit of Epidemiology and Risk Analysis Applied to Veterinary Sciences; Belgica Fil: Linares, Facundo José. Servicio Nacional de Sanidad y Calidad Agroalimentaria. Dirección Nacional de Sanidad Animal. Dirección de Epidemiología y Análisis de Riesgo; Argentina Fil: Cosentino, Bernardo. Servicio Nacional de Sanidad y Calidad Agroalimentaria. Dirección Nacional de Sanidad Animal. Dirección de Epidemiología y Análisis de Riesgo; Argentina Fil: Sago, Adrián Miguel. Servicio Nacional de Sanidad y Calidad Agroalimentaria. Centro Regional La Pampa-San Luis; Argentina Fil: La Sala, Luciano Francisco. Universidad Nacional del Sur. Bioquímica y Farmacia. Cátedra de Parasitología Cínica. Departamento de Biología; Argentina Fil: Leon, Eduardo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología. Area de Patología, Epidemiología y Medicina Preventiva; Argentina Fil: Duffy, Sergio. Universidad Nacional de Rosario. Facultad de Ciencias Veterinarias. Centro de Estudios Cuantitativos en Sanidad Animal; Argentina Fil: Perez, Andrés. University of Minnesota. College of Veterinary Medicine. Department of Veterinary Population Medicine; Estados Unidos 2019-02-20T15:14:28Z 2019-02-20T15:14:28Z 2015 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/4475 https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-015-0535-1 1746-6148 https://doi.org/10.1186/s12917-015-0535-1 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf San Luis (province) Argentina (nation) BioMed Central BMC veterinary research 11 : 209. (2015) |
| spellingShingle | Morbosidad Distribución Espacial Brucella Abortus Morbidity Spatial Distribution Prevalence Prevalencia de una Enfermedad Bovine Brucellosis Brucelosis Bovina San Luis La Pampa Aznar, Maria Natalia Linares, Facundo José Cosentino, Bernardo Sago, Adrián Miguel La Sala, Luciano Francisco Leon, Eduardo Duffy, Sergio Perez, Andrés Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, Argentina |
| title | Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, Argentina |
| title_full | Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, Argentina |
| title_fullStr | Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, Argentina |
| title_full_unstemmed | Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, Argentina |
| title_short | Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, Argentina |
| title_sort | prevalence and spatial distribution of bovine brucellosis in san luis and la pampa argentina |
| topic | Morbosidad Distribución Espacial Brucella Abortus Morbidity Spatial Distribution Prevalence Prevalencia de una Enfermedad Bovine Brucellosis Brucelosis Bovina San Luis La Pampa |
| url | http://hdl.handle.net/20.500.12123/4475 https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-015-0535-1 https://doi.org/10.1186/s12917-015-0535-1 |
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