Bovine colostral cells : the often forgotten component of colostrum
Because bovine maternal and fetal blood supplies are kept separate in utero, calves are immunologically naïve immediately after birth, which puts them at high risk for disease. The acquisition of passive immunity, generally through the ingestion of colostrum, helps protect calves against disease dur...
| Autores principales: | , |
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| Formato: | info:ar-repo/semantics/revisión literaria |
| Lenguaje: | Inglés |
| Publicado: |
American Veterinary Medical Association
2019
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12123/4445 https://avmajournals.avma.org/doi/full/10.2460/javma.250.9.998 |
| _version_ | 1855035324677226496 |
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| author | Gonzalez, Diego Dus Santos, Maria Jose |
| author_browse | Dus Santos, Maria Jose Gonzalez, Diego |
| author_facet | Gonzalez, Diego Dus Santos, Maria Jose |
| author_sort | Gonzalez, Diego |
| collection | INTA Digital |
| description | Because bovine maternal and fetal blood supplies are kept separate in utero, calves are immunologically naïve immediately after birth, which puts them at high risk for disease. The acquisition of passive immunity, generally through the ingestion of colostrum, helps protect calves against disease during this critical period. Cattle producers routinely feed newborn calves fresh (ie, never frozen) or frozen colostrum, which contains antibodies against pathogens within the local environment; however, antibodies are not the sole constituents of colostrum and passively acquired immunity. In addition to maternally derived antibodies, colostrum contains immunologically important cytokines and a large number of maternally derived (materBovine nal) leukocytes, which collectively contribute to the immunoprotection of the neonate.13–16 Although the role of colostral antibodies in the protection of neonates against disease has been well documented,17–20 the role of colostral cellular components in passive immunity is less well understood.21–28 In the early 1970s, researchers began to suggest that maternal lymphocytes in colostrum were primed antigen-responsive cells that, when ingested soon after birth, penetrate the permeable intestinal wall and provide transient local or systemic cell-mediated immunity, the breadth of which reflects the antigenic exposure of the cow from which the colostrum was acquired. |
| format | info:ar-repo/semantics/revisión literaria |
| id | INTA4445 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2019 |
| publishDateRange | 2019 |
| publishDateSort | 2019 |
| publisher | American Veterinary Medical Association |
| publisherStr | American Veterinary Medical Association |
| record_format | dspace |
| spelling | INTA44452019-02-14T17:46:11Z Bovine colostral cells : the often forgotten component of colostrum Gonzalez, Diego Dus Santos, Maria Jose Bovina Células Calostro Anticuerpos Inmunidad Bovinae Cells Colostrum Antibodies Immunity Because bovine maternal and fetal blood supplies are kept separate in utero, calves are immunologically naïve immediately after birth, which puts them at high risk for disease. The acquisition of passive immunity, generally through the ingestion of colostrum, helps protect calves against disease during this critical period. Cattle producers routinely feed newborn calves fresh (ie, never frozen) or frozen colostrum, which contains antibodies against pathogens within the local environment; however, antibodies are not the sole constituents of colostrum and passively acquired immunity. In addition to maternally derived antibodies, colostrum contains immunologically important cytokines and a large number of maternally derived (materBovine nal) leukocytes, which collectively contribute to the immunoprotection of the neonate.13–16 Although the role of colostral antibodies in the protection of neonates against disease has been well documented,17–20 the role of colostral cellular components in passive immunity is less well understood.21–28 In the early 1970s, researchers began to suggest that maternal lymphocytes in colostrum were primed antigen-responsive cells that, when ingested soon after birth, penetrate the permeable intestinal wall and provide transient local or systemic cell-mediated immunity, the breadth of which reflects the antigenic exposure of the cow from which the colostrum was acquired. Instituto de Virología Fil: Gonzalez, Diego. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina Fil: Dus Santos, Maria Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina 2019-02-14T17:38:35Z 2019-02-14T17:38:35Z 2017-05 info:ar-repo/semantics/revisión literaria info:eu-repo/semantics/review info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/4445 https://avmajournals.avma.org/doi/full/10.2460/javma.250.9.998 0003-1488 eng info:eu-repo/semantics/restrictedAccess application/pdf American Veterinary Medical Association JAVMA 250 (9) : 998-1005. (May 1, 2017) |
| spellingShingle | Bovina Células Calostro Anticuerpos Inmunidad Bovinae Cells Colostrum Antibodies Immunity Gonzalez, Diego Dus Santos, Maria Jose Bovine colostral cells : the often forgotten component of colostrum |
| title | Bovine colostral cells : the often forgotten component of colostrum |
| title_full | Bovine colostral cells : the often forgotten component of colostrum |
| title_fullStr | Bovine colostral cells : the often forgotten component of colostrum |
| title_full_unstemmed | Bovine colostral cells : the often forgotten component of colostrum |
| title_short | Bovine colostral cells : the often forgotten component of colostrum |
| title_sort | bovine colostral cells the often forgotten component of colostrum |
| topic | Bovina Células Calostro Anticuerpos Inmunidad Bovinae Cells Colostrum Antibodies Immunity |
| url | http://hdl.handle.net/20.500.12123/4445 https://avmajournals.avma.org/doi/full/10.2460/javma.250.9.998 |
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