Tobacco and end stage renal disease: a multicenter, cross-sectional study in Argentinian Northern Patagonia
Background: Smoking and chronic kidney disease are major public health problems with common features -high prevalence and mortality, high cardiovascular risk, gender differences and high prevalence in low income people-, but the link between them is poorly recognized. Our objectives were to investig...
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| Format: | Artículo |
| Language: | Inglés |
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International Society for the Prevention of Tobacco Induced Diseases
2018
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| Online Access: | http://www.tobaccoinduceddiseases.org/Tobacco-and-end-stage-renal-disease-a-multicenter-cross-sectional-study-in-Argentinian,67186,0,2.html http://hdl.handle.net/20.500.12123/4039 https://doi.org/10.1186/s12971-015-0051-x |
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| author | Alba, Maria M. Citarelli, Alicia N. Menni, María Fernanda Agricola, Maria Braicovich, Alejandra De Horta, Eduardo De Rosa, Fernando Filanino, Graciela Gaggiotti, Raul Junqueras, Nelson Martinelli, Sandra Milan, Adriana Morales, Mabel E. Setti, Silvia Villalba, Daniel O. |
| author_browse | Agricola, Maria Alba, Maria M. Braicovich, Alejandra Citarelli, Alicia N. De Horta, Eduardo De Rosa, Fernando Filanino, Graciela Gaggiotti, Raul Junqueras, Nelson Martinelli, Sandra Menni, María Fernanda Milan, Adriana Morales, Mabel E. Setti, Silvia Villalba, Daniel O. |
| author_facet | Alba, Maria M. Citarelli, Alicia N. Menni, María Fernanda Agricola, Maria Braicovich, Alejandra De Horta, Eduardo De Rosa, Fernando Filanino, Graciela Gaggiotti, Raul Junqueras, Nelson Martinelli, Sandra Milan, Adriana Morales, Mabel E. Setti, Silvia Villalba, Daniel O. |
| author_sort | Alba, Maria M. |
| collection | INTA Digital |
| description | Background: Smoking and chronic kidney disease are major public health problems with common features -high prevalence and mortality, high cardiovascular risk, gender differences and high prevalence in low income people-, but the link between them is poorly recognized. Our objectives were to investigate the exposure of dialysis patients to tobacco and to know their smoking behavior.
Methods: We performed a multicenter, cross-sectional study in nine dialysis units in the Argentinian Northern Patagonia. We investigated smoker status, lifetime tobacco consumption, current tobacco use, breath carbon monoxide and % carboxyhaemoglobin. Fagerström and Richmond tests were performed for active smokers. Statistical analysis: one way ANOVA and Tukey’s test for post hoc test. For exploratory analysis, frequency tables through chi-square distribution and single correspondence analysis were performed.
Results: Six hundred thirty six patients (60.9 % males, 39.1 % females) were interviewed. Almost 70 % of them had had tobacco exposure. Excluding light smokers, the lifetime consumption was significantly different (p = 0.0052) between sexes (33.1 ± 2.4 pack/years in males and 18.2 ± 2.1 pack/years in females) The distribution of etiologies changed significantly (χ 2 p < 0.0001) with smoker status and the dose of tobacco smoking, with an increase in the diagnosis of nephrosclerosis in patients with high and very high lifetime consumption (from 16.1 % in non-smokers to 28.2 and 27 % respectively), and in passive smokers (from 16.1 to 27.3 %). The male preponderance of end-stage renal disease disappeared when only non-smokers were considered and grew with the increase in the lifetime consumption. Active smokers have small consumption, both low CO level and % COHb, low dependence and a good motivation to quit, but a high lifetime consumption.
Conclusions: Exposure of dialysis patients to tobacco is high and could be related to the progression to the final stage of the renal disease. It seems that tobacco renal damage is mostly hidden in the diagnosis of nephrosclerosis. The gender difference observed in these patients could also have a nexus with the men’s higher tobacco exposure. Active smokers have a low current consumption but a high lifetime tobacco dose. |
| format | Artículo |
| id | INTA4039 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2018 |
| publishDateRange | 2018 |
| publishDateSort | 2018 |
| publisher | International Society for the Prevention of Tobacco Induced Diseases |
| publisherStr | International Society for the Prevention of Tobacco Induced Diseases |
| record_format | dspace |
| spelling | INTA40392018-12-12T19:00:19Z Tobacco and end stage renal disease: a multicenter, cross-sectional study in Argentinian Northern Patagonia Alba, Maria M. Citarelli, Alicia N. Menni, María Fernanda Agricola, Maria Braicovich, Alejandra De Horta, Eduardo De Rosa, Fernando Filanino, Graciela Gaggiotti, Raul Junqueras, Nelson Martinelli, Sandra Milan, Adriana Morales, Mabel E. Setti, Silvia Villalba, Daniel O. Enfermedades Renales Enfermedades Humanas Tabaco Salud Pública Kidney Diseases Human Diseases Tobacco Public Health Tabaquismo Región Patagónica Background: Smoking and chronic kidney disease are major public health problems with common features -high prevalence and mortality, high cardiovascular risk, gender differences and high prevalence in low income people-, but the link between them is poorly recognized. Our objectives were to investigate the exposure of dialysis patients to tobacco and to know their smoking behavior. Methods: We performed a multicenter, cross-sectional study in nine dialysis units in the Argentinian Northern Patagonia. We investigated smoker status, lifetime tobacco consumption, current tobacco use, breath carbon monoxide and % carboxyhaemoglobin. Fagerström and Richmond tests were performed for active smokers. Statistical analysis: one way ANOVA and Tukey’s test for post hoc test. For exploratory analysis, frequency tables through chi-square distribution and single correspondence analysis were performed. Results: Six hundred thirty six patients (60.9 % males, 39.1 % females) were interviewed. Almost 70 % of them had had tobacco exposure. Excluding light smokers, the lifetime consumption was significantly different (p = 0.0052) between sexes (33.1 ± 2.4 pack/years in males and 18.2 ± 2.1 pack/years in females) The distribution of etiologies changed significantly (χ 2 p < 0.0001) with smoker status and the dose of tobacco smoking, with an increase in the diagnosis of nephrosclerosis in patients with high and very high lifetime consumption (from 16.1 % in non-smokers to 28.2 and 27 % respectively), and in passive smokers (from 16.1 to 27.3 %). The male preponderance of end-stage renal disease disappeared when only non-smokers were considered and grew with the increase in the lifetime consumption. Active smokers have small consumption, both low CO level and % COHb, low dependence and a good motivation to quit, but a high lifetime consumption. Conclusions: Exposure of dialysis patients to tobacco is high and could be related to the progression to the final stage of the renal disease. It seems that tobacco renal damage is mostly hidden in the diagnosis of nephrosclerosis. The gender difference observed in these patients could also have a nexus with the men’s higher tobacco exposure. Active smokers have a low current consumption but a high lifetime tobacco dose. EEA Alto Valle Fil: Alba, Maria M. Northern Patagonia Association of Nephrology; Argentina. Unidad Renal Cipolletti SA; Argentina Fil: Citarelli, Alicia N. Northern Patagonia Association of Nephrology; Argentina Fil: Menni, María Fernanda. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Alto Valle; Argentina Fil: Agricola, Maria. Northern Patagonia Association of Nephrology; Argentina Fil: Braicovich, Alejandra. Northern Patagonia Association of Nephrology; Argentina Fil: De Horta, Eduardo. Northern Patagonia Association of Nephrology; Argentina Fil: De Rosa, Fernando. Northern Patagonia Association of Nephrology; Argentina Fil: Filanino, Graciela. Northern Patagonia Association of Nephrology; Argentina Fil: Gaggiotti, Raul. Northern Patagonia Association of Nephrology; Argentina Fil: Junqueras, Nelson. Northern Patagonia Association of Nephrology; Argentina Fil: Martinelli, Sandra. Northern Patagonia Association of Nephrology; Argentina Fil: Milan, Adriana. Northern Patagonia Association of Nephrology; Argentina Fil: Morales, Mabel E.. Northern Patagonia Association of Nephrology; Argentina Fil: Setti, Silvia. Northern Patagonia Association of Nephrology; Argentina Fil: Villalba, Daniel O. Unidad Renal Cipolletti SA; Argentina 2018-12-10T13:55:58Z 2018-12-10T13:55:58Z 2015-09 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://www.tobaccoinduceddiseases.org/Tobacco-and-end-stage-renal-disease-a-multicenter-cross-sectional-study-in-Argentinian,67186,0,2.html http://hdl.handle.net/20.500.12123/4039 1617-9625 https://doi.org/10.1186/s12971-015-0051-x eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf International Society for the Prevention of Tobacco Induced Diseases Tobacco Induced Diseases 13 : 28 (September 2015) |
| spellingShingle | Enfermedades Renales Enfermedades Humanas Tabaco Salud Pública Kidney Diseases Human Diseases Tobacco Public Health Tabaquismo Región Patagónica Alba, Maria M. Citarelli, Alicia N. Menni, María Fernanda Agricola, Maria Braicovich, Alejandra De Horta, Eduardo De Rosa, Fernando Filanino, Graciela Gaggiotti, Raul Junqueras, Nelson Martinelli, Sandra Milan, Adriana Morales, Mabel E. Setti, Silvia Villalba, Daniel O. Tobacco and end stage renal disease: a multicenter, cross-sectional study in Argentinian Northern Patagonia |
| title | Tobacco and end stage renal disease: a multicenter, cross-sectional study in Argentinian Northern Patagonia |
| title_full | Tobacco and end stage renal disease: a multicenter, cross-sectional study in Argentinian Northern Patagonia |
| title_fullStr | Tobacco and end stage renal disease: a multicenter, cross-sectional study in Argentinian Northern Patagonia |
| title_full_unstemmed | Tobacco and end stage renal disease: a multicenter, cross-sectional study in Argentinian Northern Patagonia |
| title_short | Tobacco and end stage renal disease: a multicenter, cross-sectional study in Argentinian Northern Patagonia |
| title_sort | tobacco and end stage renal disease a multicenter cross sectional study in argentinian northern patagonia |
| topic | Enfermedades Renales Enfermedades Humanas Tabaco Salud Pública Kidney Diseases Human Diseases Tobacco Public Health Tabaquismo Región Patagónica |
| url | http://www.tobaccoinduceddiseases.org/Tobacco-and-end-stage-renal-disease-a-multicenter-cross-sectional-study-in-Argentinian,67186,0,2.html http://hdl.handle.net/20.500.12123/4039 https://doi.org/10.1186/s12971-015-0051-x |
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