Evaluation of Tritrichomonas foetus infection clearance in heifers immunized with a single intravaginal dose of formaldehyde fixed strain B1 cells
Vaccines against Tritrichomonas foetus have been shown to reduce the time of infection after natural or experimental exposure. The object of this study was to assess the protection against T. foetus infection conferred by a single vaginal instillation of formaldehyde fixed T. foetus cells. Aberdeen...
| Autores principales: | , , , , |
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| Formato: | info:ar-repo/semantics/artículo |
| Lenguaje: | Inglés |
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Elsevier
2018
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12123/3938 https://www.sciencedirect.com/science/article/pii/S0304401718301213?via%3Dihub https://doi.org/10.1016/j.vetpar.2018.03.019 |
| _version_ | 1855035231361302528 |
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| author | Martinez, Florencia Gracia Fuchs, Lumila Ivana Ramirez, Rosana Breccia, Javier Dario Oyhenart, Jorge |
| author_browse | Breccia, Javier Dario Fuchs, Lumila Ivana Martinez, Florencia Gracia Oyhenart, Jorge Ramirez, Rosana |
| author_facet | Martinez, Florencia Gracia Fuchs, Lumila Ivana Ramirez, Rosana Breccia, Javier Dario Oyhenart, Jorge |
| author_sort | Martinez, Florencia Gracia |
| collection | INTA Digital |
| description | Vaccines against Tritrichomonas foetus have been shown to reduce the time of infection after natural or experimental exposure. The object of this study was to assess the protection against T. foetus infection conferred by a single vaginal instillation of formaldehyde fixed T. foetus cells. Aberdeen Angus virgin heifers were randomly allocated to 3 groups of 12 individuals to receive placebo or formaldehyde fixed T. foetus cells prepared following one of two procedures (formalin or freshly prepared solution) and six weeks later they were challenged with 106T. foetus trophozoites. The median time for clearance among control heifers was 93.75 days while in animals immunized with formaldehyde fixed T. foetus it was 45 days. A single vaginal dose of cells fixed with fresh formaldehyde solution gave a rate of decay of infection per unit of time of 2.54 (CI 95% = 1.07;6.01). |
| format | info:ar-repo/semantics/artículo |
| id | INTA3938 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2018 |
| publishDateRange | 2018 |
| publishDateSort | 2018 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | INTA39382018-11-21T14:10:24Z Evaluation of Tritrichomonas foetus infection clearance in heifers immunized with a single intravaginal dose of formaldehyde fixed strain B1 cells Martinez, Florencia Gracia Fuchs, Lumila Ivana Ramirez, Rosana Breccia, Javier Dario Oyhenart, Jorge Tritrichomonas Foetus Novilla Vacuna Bovina Inmunización Infección Heifers Vaccines Bovinae Immunization Infection Vaccines against Tritrichomonas foetus have been shown to reduce the time of infection after natural or experimental exposure. The object of this study was to assess the protection against T. foetus infection conferred by a single vaginal instillation of formaldehyde fixed T. foetus cells. Aberdeen Angus virgin heifers were randomly allocated to 3 groups of 12 individuals to receive placebo or formaldehyde fixed T. foetus cells prepared following one of two procedures (formalin or freshly prepared solution) and six weeks later they were challenged with 106T. foetus trophozoites. The median time for clearance among control heifers was 93.75 days while in animals immunized with formaldehyde fixed T. foetus it was 45 days. A single vaginal dose of cells fixed with fresh formaldehyde solution gave a rate of decay of infection per unit of time of 2.54 (CI 95% = 1.07;6.01). EEA Anguil Fil: Martinez, Florencia Gracia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Ciencias de la Tierra y Ambientales de La Pampa. Universidad Nacional de La Pampa. Facultad de Ciencias Exactas y Naturales. Instituto de Ciencias de la Tierra y Ambientales de La Pampa; Argentina Fil: Fuchs, Lumila Ivana. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil; Argentina Fil: Ramirez, Rosana. Universidad Nacional del Litoral; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Breccia, Javier Dario. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Ciencias de la Tierra y Ambientales de La Pampa. Universidad Nacional de La Pampa. Facultad de Ciencias Exactas y Naturales. Instituto de Ciencias de la Tierra y Ambientales de La Pampa; Argentina Fil: Oyhenart, Jorge. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Ciencias de la Tierra y Ambientales de La Pampa. Universidad Nacional de La Pampa. Facultad de Ciencias Exactas y Naturales. Instituto de Ciencias de la Tierra y Ambientales de La Pampa; Argentina 2018-11-21T14:04:19Z 2018-11-21T14:04:19Z 2018-05-15 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/3938 https://www.sciencedirect.com/science/article/pii/S0304401718301213?via%3Dihub 0304-4017 https://doi.org/10.1016/j.vetpar.2018.03.019 eng info:eu-repo/semantics/restrictedAccess application/pdf Elsevier Veterinary parasitology 255 : 32-37. (15 May 2018) |
| spellingShingle | Tritrichomonas Foetus Novilla Vacuna Bovina Inmunización Infección Heifers Vaccines Bovinae Immunization Infection Martinez, Florencia Gracia Fuchs, Lumila Ivana Ramirez, Rosana Breccia, Javier Dario Oyhenart, Jorge Evaluation of Tritrichomonas foetus infection clearance in heifers immunized with a single intravaginal dose of formaldehyde fixed strain B1 cells |
| title | Evaluation of Tritrichomonas foetus infection clearance in heifers immunized with a single intravaginal dose of formaldehyde fixed strain B1 cells |
| title_full | Evaluation of Tritrichomonas foetus infection clearance in heifers immunized with a single intravaginal dose of formaldehyde fixed strain B1 cells |
| title_fullStr | Evaluation of Tritrichomonas foetus infection clearance in heifers immunized with a single intravaginal dose of formaldehyde fixed strain B1 cells |
| title_full_unstemmed | Evaluation of Tritrichomonas foetus infection clearance in heifers immunized with a single intravaginal dose of formaldehyde fixed strain B1 cells |
| title_short | Evaluation of Tritrichomonas foetus infection clearance in heifers immunized with a single intravaginal dose of formaldehyde fixed strain B1 cells |
| title_sort | evaluation of tritrichomonas foetus infection clearance in heifers immunized with a single intravaginal dose of formaldehyde fixed strain b1 cells |
| topic | Tritrichomonas Foetus Novilla Vacuna Bovina Inmunización Infección Heifers Vaccines Bovinae Immunization Infection |
| url | http://hdl.handle.net/20.500.12123/3938 https://www.sciencedirect.com/science/article/pii/S0304401718301213?via%3Dihub https://doi.org/10.1016/j.vetpar.2018.03.019 |
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