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Canarypox virus expressing infectious bursal disease VP2 protein as immunogen for chickens

Canarypox viruses (CNPV) carrying the coding sequence of VP2 protein from infectious bursal disease virus (IBDV) were obtained. These viruses were able to express VP2 protein in vitro and to induce IBDV-neutralizing antibodies when inoculated in specific pathogen-free chickens demonstrating that CN...

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Main Authors: Zanetti, Flavia Adriana, Conte Grand, María Daniela, Mitarotonda, Romina Cristina, Taboga, Oscar Alberto, Calamante, Gabriela
Format: Artículo
Language:Inglés
Published: Sociedade Brasileira de Microbiologia 2018
Subjects:
Virus bursitis infecciosa
Pollo
Anticuerpos
Infectious bursal disease virus
Chickens
Antibodies
Canarypox Virus
Proteína VP2
VP2 Protein
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059302/
http://hdl.handle.net/20.500.12123/3578
http://dx.doi.org/10.1590/S1517-83822014000100032
Summary:Canarypox viruses (CNPV) carrying the coding sequence of VP2 protein from infectious bursal disease virus (IBDV) were obtained. These viruses were able to express VP2 protein in vitro and to induce IBDV-neutralizing antibodies when inoculated in specific pathogen-free chickens demonstrating that CNPV platform is usefulness to develop immunogens for chickens.

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