Effects of IFN-γ coding plasmid supplementation in the immune response and protection elicited by Trypanosoma cruzi attenuated parasites

Background: Previous studies showed that a naturally attenuated strain from Trypanosoma cruzi triggers an immune response mainly related to a Th2-type profile. Albeit this, a strong protection against virulent challenge was obtained after priming mice with this attenuated strain. However, this pro...

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Bibliographic Details
Main Authors: Pérez Brandan, Cecilia María, Mesías, Andrea Cecilia, Parodi Ramoneda, Cecilia María, Cimino, Rubén Oscar, Perez Brandan, Carolina, Diosque, Patricio, Basombrío, Miguel Angel Manuel
Format: Artículo
Language:Inglés
Published: BioMed Central 2018
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Online Access:http://hdl.handle.net/20.500.12123/2884
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702110/

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