Effects of probiotics in swines growth performance: A meta-analysis of randomised controlled trials

The objective of this meta-analysis was to assess effects of probiotics on the growth performance of pigs (Average Daily Gain (ADG) and Feed Efficiency (FE)). Data bases (i.e. PubMed, ScienceDirect, and Scopus) were searched from 1980 to 2015 unrestricted by language. The inclusion criteria were: ra...

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Autores principales: Zimmermann, Jorge Alberto, Fusari, Marcia Lucia, Rossler, Eugenia, Blajman, Jesica E., Romero Scharpen, Analía, Astesana, Diego Martín, Olivero, Carolina Raquel, Berisvil, Ayelén Patricia, Signorini, Marcelo, Zbrun, María Virginia, Frizzo, Laureano Sebastian, Soto, Lorena Paola
Formato: Artículo
Lenguaje:Inglés
Publicado: 2018
Materias:
Acceso en línea:https://www.sciencedirect.com/science/article/pii/S0377840116302784
http://hdl.handle.net/20.500.12123/2795
https://doi.org/10.1016/j.anifeedsci.2016.06.021
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author Zimmermann, Jorge Alberto
Fusari, Marcia Lucia
Rossler, Eugenia
Blajman, Jesica E.
Romero Scharpen, Analía
Astesana, Diego Martín
Olivero, Carolina Raquel
Berisvil, Ayelén Patricia
Signorini, Marcelo
Zbrun, María Virginia
Frizzo, Laureano Sebastian
Soto, Lorena Paola
author_browse Astesana, Diego Martín
Berisvil, Ayelén Patricia
Blajman, Jesica E.
Frizzo, Laureano Sebastian
Fusari, Marcia Lucia
Olivero, Carolina Raquel
Romero Scharpen, Analía
Rossler, Eugenia
Signorini, Marcelo
Soto, Lorena Paola
Zbrun, María Virginia
Zimmermann, Jorge Alberto
author_facet Zimmermann, Jorge Alberto
Fusari, Marcia Lucia
Rossler, Eugenia
Blajman, Jesica E.
Romero Scharpen, Analía
Astesana, Diego Martín
Olivero, Carolina Raquel
Berisvil, Ayelén Patricia
Signorini, Marcelo
Zbrun, María Virginia
Frizzo, Laureano Sebastian
Soto, Lorena Paola
author_sort Zimmermann, Jorge Alberto
collection INTA Digital
description The objective of this meta-analysis was to assess effects of probiotics on the growth performance of pigs (Average Daily Gain (ADG) and Feed Efficiency (FE)). Data bases (i.e. PubMed, ScienceDirect, and Scopus) were searched from 1980 to 2015 unrestricted by language. The inclusion criteria were: randomised and controlled experiments using pigs without apparent disease and published in peer reviewed journals. Sixty-seven and 60 experiments were included to assess probiotic effects on ADG and FE, respectively. LAB supplementation increased ADG (difference in mean (DM) = 29.930 g/day, 95% confidence interval (CI) 17.617–42.261) and improve feed efficiency (DM = −0.096 kg feed/kg body weight, 95%CI −0.120–0.071), considering the source of heterogeneity. There were no evidence of publication biases. The meta-analysis showed that application of probiotics during the first stage of pig grown and in the finishing period resulted in greater ADG and FE. The effect was not related to the use of mono-strain or multi-strain probiotics, although it may depend on the strain used. The breeds (especially F1 and three-breed-rotational crossbreeding) and the characteristic of these breeds (maternal breeds) included in the experiments had an impact on the outcomes. These results might be used to define the guidelines to standardize the experimental designs of future trials and to include the impact of each covariate on the differences in the estimated effect sizes.
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spelling INTA27952018-07-16T15:23:34Z Effects of probiotics in swines growth performance: A meta-analysis of randomised controlled trials Zimmermann, Jorge Alberto Fusari, Marcia Lucia Rossler, Eugenia Blajman, Jesica E. Romero Scharpen, Analía Astesana, Diego Martín Olivero, Carolina Raquel Berisvil, Ayelén Patricia Signorini, Marcelo Zbrun, María Virginia Frizzo, Laureano Sebastian Soto, Lorena Paola Cerdo Probióticos Período de Crecimiento Experimentación Bacterias Acidolácticas Peso Corporal Swine Probiotics Growth Period Experimentation Lactic Acid Bacteria Body Weight The objective of this meta-analysis was to assess effects of probiotics on the growth performance of pigs (Average Daily Gain (ADG) and Feed Efficiency (FE)). Data bases (i.e. PubMed, ScienceDirect, and Scopus) were searched from 1980 to 2015 unrestricted by language. The inclusion criteria were: randomised and controlled experiments using pigs without apparent disease and published in peer reviewed journals. Sixty-seven and 60 experiments were included to assess probiotic effects on ADG and FE, respectively. LAB supplementation increased ADG (difference in mean (DM) = 29.930 g/day, 95% confidence interval (CI) 17.617–42.261) and improve feed efficiency (DM = −0.096 kg feed/kg body weight, 95%CI −0.120–0.071), considering the source of heterogeneity. There were no evidence of publication biases. The meta-analysis showed that application of probiotics during the first stage of pig grown and in the finishing period resulted in greater ADG and FE. The effect was not related to the use of mono-strain or multi-strain probiotics, although it may depend on the strain used. The breeds (especially F1 and three-breed-rotational crossbreeding) and the characteristic of these breeds (maternal breeds) included in the experiments had an impact on the outcomes. These results might be used to define the guidelines to standardize the experimental designs of future trials and to include the impact of each covariate on the differences in the estimated effect sizes. EEA Rafaela Fil: Zimmermann, Jorge Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Ciencias Veterinarias del Litoral. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Instituto de Ciencias Veterinarias del Litoral; Argentina Fil: Fusari, Marcia Lucia. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública; Argentina Fil: Rossler, Eugenia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Ciencias Veterinarias del Litoral. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Instituto de Ciencias Veterinarias del Litoral; Argentina Fil: Blajman, Jesica E. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Ciencias Veterinarias del Litoral. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Instituto de Ciencias Veterinarias del Litoral; Argentina Fil: Romero Scharpen, Analía. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Ciencias Veterinarias del Litoral. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Instituto de Ciencias Veterinarias del Litoral; Argentina Fil: Astesana, Diego Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Ciencias Veterinarias del Litoral. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Instituto de Ciencias Veterinarias del Litoral; Argentina Fil: Olivero, Carolina Raquel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Ciencias Veterinarias del Litoral. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Instituto de Ciencias Veterinarias del Litoral; Argentina Fil: Berisvil, Ayelén Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Ciencias Veterinarias del Litoral. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Instituto de Ciencias Veterinarias del Litoral; Argentina Fil: Signorini, Marcelo. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina Fil: Zbrun, María Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Ciencias Veterinarias del Litoral. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Instituto de Ciencias Veterinarias del Litoral; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública; Argentina Fil: Frizzo, Laureano Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Ciencias Veterinarias del Litoral. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Instituto de Ciencias Veterinarias del Litoral; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública; Argentina Fil: Soto, Lorena Paola. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Ciencias Veterinarias del Litoral. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Instituto de Ciencias Veterinarias del Litoral; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública; Argentina 2018-07-16T15:21:52Z 2018-07-16T15:21:52Z 2016-09 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://www.sciencedirect.com/science/article/pii/S0377840116302784 http://hdl.handle.net/20.500.12123/2795 0377-8401 https://doi.org/10.1016/j.anifeedsci.2016.06.021 eng info:eu-repo/semantics/restrictedAccess application/pdf Animal Feed Science and Technology 219 : 280-293 (September 2016)
spellingShingle Cerdo
Probióticos
Período de Crecimiento
Experimentación
Bacterias Acidolácticas
Peso Corporal
Swine
Probiotics
Growth Period
Experimentation
Lactic Acid Bacteria
Body Weight
Zimmermann, Jorge Alberto
Fusari, Marcia Lucia
Rossler, Eugenia
Blajman, Jesica E.
Romero Scharpen, Analía
Astesana, Diego Martín
Olivero, Carolina Raquel
Berisvil, Ayelén Patricia
Signorini, Marcelo
Zbrun, María Virginia
Frizzo, Laureano Sebastian
Soto, Lorena Paola
Effects of probiotics in swines growth performance: A meta-analysis of randomised controlled trials
title Effects of probiotics in swines growth performance: A meta-analysis of randomised controlled trials
title_full Effects of probiotics in swines growth performance: A meta-analysis of randomised controlled trials
title_fullStr Effects of probiotics in swines growth performance: A meta-analysis of randomised controlled trials
title_full_unstemmed Effects of probiotics in swines growth performance: A meta-analysis of randomised controlled trials
title_short Effects of probiotics in swines growth performance: A meta-analysis of randomised controlled trials
title_sort effects of probiotics in swines growth performance a meta analysis of randomised controlled trials
topic Cerdo
Probióticos
Período de Crecimiento
Experimentación
Bacterias Acidolácticas
Peso Corporal
Swine
Probiotics
Growth Period
Experimentation
Lactic Acid Bacteria
Body Weight
url https://www.sciencedirect.com/science/article/pii/S0377840116302784
http://hdl.handle.net/20.500.12123/2795
https://doi.org/10.1016/j.anifeedsci.2016.06.021
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