Probiotics and broiler growth performance: a meta-analysis of randomised controlled trials

1. The aim of this meta-analysis was to investigate the effects of probiotics on the growth performance of broilers. PubMed, Scopus and Scholar Google databases were searched in all languages from 1980 to 2012. The studies in the meta-analysis were only selected if they were randomised and controlle...

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Main Authors: Blajman, Jesica E., Frizzo, Laureano Sebastian, Zbrun, María Virginia, Astesana, Diego Martín, Fusari, Marcia Lucia, Soto, Lorena Paola, Rosmini, Marcelo Raúl, Signorini, Marcelo
Format: info:ar-repo/semantics/artículo
Language:Inglés
Published: 2018
Subjects:
Online Access:https://www.tandfonline.com/doi/abs/10.1080/00071668.2014.931930
http://hdl.handle.net/20.500.12123/2778
https://doi.org/10.1080/00071668.2014.931930
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author Blajman, Jesica E.
Frizzo, Laureano Sebastian
Zbrun, María Virginia
Astesana, Diego Martín
Fusari, Marcia Lucia
Soto, Lorena Paola
Rosmini, Marcelo Raúl
Signorini, Marcelo
author_browse Astesana, Diego Martín
Blajman, Jesica E.
Frizzo, Laureano Sebastian
Fusari, Marcia Lucia
Rosmini, Marcelo Raúl
Signorini, Marcelo
Soto, Lorena Paola
Zbrun, María Virginia
author_facet Blajman, Jesica E.
Frizzo, Laureano Sebastian
Zbrun, María Virginia
Astesana, Diego Martín
Fusari, Marcia Lucia
Soto, Lorena Paola
Rosmini, Marcelo Raúl
Signorini, Marcelo
author_sort Blajman, Jesica E.
collection INTA Digital
description 1. The aim of this meta-analysis was to investigate the effects of probiotics on the growth performance of broilers. PubMed, Scopus and Scholar Google databases were searched in all languages from 1980 to 2012. The studies in the meta-analysis were only selected if they were randomised and controlled experiments using broilers without apparent disease and the results were published in peer-reviewed journals. 2. A total of 48 and 46 studies were included to assess probiotic effects on body weight gain (BWG) and feed efficiency (FE), respectively. Probiotics increased BWG compared to controls (SMD = 0.661, 95% CI 0.499 to 0.822) and improved FE (SMD = − 0.281, 95% CI −0.404 to −0.157) in the pooled standardised mean difference random effect model, considering the source of heterogeneity and publication biases. However, there are evidences of publication bias and heterogeneity, so the results of this meta-analysis should be considered with caution. Applying the Duval and Tweedie’s trim-and-fill methods, the adjusted value for BWG was 0.0594 (95% CI −0.122 to 0.242), and the adjusted value for FE did not show any modifications. 3. The meta-analysis showed that application of probiotics via water resulted in greater BGW and FE than administration through the feed. The effect was not related to the use of mono-strain or multi-strain probiotics, although it may depend on the strain used. The number of broilers and the duration of the experiments had an impact on the outcomes. 4. Additional studies should be conducted with the aim to identify the covariates which can explain the differences in the estimated effect sizes.
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institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
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spelling INTA27782018-07-12T15:16:46Z Probiotics and broiler growth performance: a meta-analysis of randomised controlled trials Blajman, Jesica E. Frizzo, Laureano Sebastian Zbrun, María Virginia Astesana, Diego Martín Fusari, Marcia Lucia Soto, Lorena Paola Rosmini, Marcelo Raúl Signorini, Marcelo Pollo de Engorde Período de Crecimiento Probióticos Experimentación Peso Corporal Broiler Chickens Growth Period Probiotics Experimentation Body Weight 1. The aim of this meta-analysis was to investigate the effects of probiotics on the growth performance of broilers. PubMed, Scopus and Scholar Google databases were searched in all languages from 1980 to 2012. The studies in the meta-analysis were only selected if they were randomised and controlled experiments using broilers without apparent disease and the results were published in peer-reviewed journals. 2. A total of 48 and 46 studies were included to assess probiotic effects on body weight gain (BWG) and feed efficiency (FE), respectively. Probiotics increased BWG compared to controls (SMD = 0.661, 95% CI 0.499 to 0.822) and improved FE (SMD = − 0.281, 95% CI −0.404 to −0.157) in the pooled standardised mean difference random effect model, considering the source of heterogeneity and publication biases. However, there are evidences of publication bias and heterogeneity, so the results of this meta-analysis should be considered with caution. Applying the Duval and Tweedie’s trim-and-fill methods, the adjusted value for BWG was 0.0594 (95% CI −0.122 to 0.242), and the adjusted value for FE did not show any modifications. 3. The meta-analysis showed that application of probiotics via water resulted in greater BGW and FE than administration through the feed. The effect was not related to the use of mono-strain or multi-strain probiotics, although it may depend on the strain used. The number of broilers and the duration of the experiments had an impact on the outcomes. 4. Additional studies should be conducted with the aim to identify the covariates which can explain the differences in the estimated effect sizes. EEA Rafaela Fil: Blajman, Jesica E. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Ciencias Veterinarias del Litoral. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Instituto de Ciencias Veterinarias del Litoral; Argentina Fil: Frizzo, Laureano Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Ciencias Veterinarias del Litoral. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Instituto de Ciencias Veterinarias del Litoral; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública; Argentina Fil: Zbrun, María Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Ciencias Veterinarias del Litoral. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Instituto de Ciencias Veterinarias del Litoral; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública; Argentina Fil: Astesana, Diego Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Ciencias Veterinarias del Litoral. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Instituto de Ciencias Veterinarias del Litoral; Argentina Fil: Fusari, Marcia Lucia. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública; Argentina Fil: Soto, Lorena Paola. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Ciencias Veterinarias del Litoral. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Instituto de Ciencias Veterinarias del Litoral; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública; Argentina Fil: Rosmini, Marcelo Raúl. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública; Argentina Fil: Signorini, Marcelo. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Departamento de Salud Pública; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina 2018-07-12T15:15:22Z 2018-07-12T15:15:22Z 2014-08 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://www.tandfonline.com/doi/abs/10.1080/00071668.2014.931930 http://hdl.handle.net/20.500.12123/2778 0007-1668 1466-1799 https://doi.org/10.1080/00071668.2014.931930 eng info:eu-repo/semantics/restrictedAccess application/pdf British Poultry Science 55 (4) : 483-494 (2014)
spellingShingle Pollo de Engorde
Período de Crecimiento
Probióticos
Experimentación
Peso Corporal
Broiler Chickens
Growth Period
Probiotics
Experimentation
Body Weight
Blajman, Jesica E.
Frizzo, Laureano Sebastian
Zbrun, María Virginia
Astesana, Diego Martín
Fusari, Marcia Lucia
Soto, Lorena Paola
Rosmini, Marcelo Raúl
Signorini, Marcelo
Probiotics and broiler growth performance: a meta-analysis of randomised controlled trials
title Probiotics and broiler growth performance: a meta-analysis of randomised controlled trials
title_full Probiotics and broiler growth performance: a meta-analysis of randomised controlled trials
title_fullStr Probiotics and broiler growth performance: a meta-analysis of randomised controlled trials
title_full_unstemmed Probiotics and broiler growth performance: a meta-analysis of randomised controlled trials
title_short Probiotics and broiler growth performance: a meta-analysis of randomised controlled trials
title_sort probiotics and broiler growth performance a meta analysis of randomised controlled trials
topic Pollo de Engorde
Período de Crecimiento
Probióticos
Experimentación
Peso Corporal
Broiler Chickens
Growth Period
Probiotics
Experimentation
Body Weight
url https://www.tandfonline.com/doi/abs/10.1080/00071668.2014.931930
http://hdl.handle.net/20.500.12123/2778
https://doi.org/10.1080/00071668.2014.931930
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