Novel Butyrylcholinesterase Inhibitor Alkaloids from Cannabis sativa Roots: Bioguided Isolation and In Silico Study

Neurodegenerative diseases, including Alzheimer’s disease (AD), represent one of the main global health challenges. Cannabis sativa synthesizes spermidine-type alkaloids, whose potential biological activities have been little studied. This study aimed to isolate bioactive alkaloids from an alkaloid-...

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Bibliographic Details

Main Authors:	Ortiz, Javier Esteban, Adarvez Feresin, Camila Wadía, Llalla Cordova, Olimpia, Cristos, Diego Sebastian, Garro, Adriana Deolinda, Feresin, Gabriela Egly
Format:	Artículo
Language:	Inglés
Published:	Multidisciplinary Digital Publishing Institute (MDPI) 2025
Subjects:	Cannabis sativa Raíz Espermidina Alcaloide Roots Spermidine Alkaloids Butyrylcholinesterase Cannabisativine Anhydrocannabisativine
Online Access:	http://hdl.handle.net/20.500.12123/23831 https://www.mdpi.com/2673-6918/5/3/35 https://doi.org/10.3390/compounds5030035