Simultaneous supplementation of the microbial fraction of kefir containing Lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance, gut microbiota, and health parameters in broiler chickens

Kefir contains lactic acid bacteria and yeasts, which are involved in fermentation and contribute to its probiotic effects. The simultaneous supplementation feeding of antibiotics and probiotics could serve as a way to replace antibiotic growth promoters (AGP) gradually. So, this study was conducted...

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Main Authors: Franco, Mariana C., Soria, Mario, Federico, Francisco Javier, Zapata, Roberto A., Hamet, María Fernanda, Gallinger, Claudia Isabel, De Antoni, Graciela L., Peláez, Angela M.L., Basiouni, Shereen, Bueno, Dante Javier
Format: info:ar-repo/semantics/artículo
Language:Inglés
Published: German Multidisciplinary Publishing Center (GMPC) 2025
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Online Access:http://hdl.handle.net/20.500.12123/23185
https://gmpc-akademie.de/articles/gjvr/single/275
https://doi.org/10.51585/gjvr.2025.2.0136
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author Franco, Mariana C.
Soria, Mario
Federico, Francisco Javier
Zapata, Roberto A.
Hamet, María Fernanda
Gallinger, Claudia Isabel
De Antoni, Graciela L.
Peláez, Angela M.L.
Basiouni, Shereen
Bueno, Dante Javier
author_browse Basiouni, Shereen
Bueno, Dante Javier
De Antoni, Graciela L.
Federico, Francisco Javier
Franco, Mariana C.
Gallinger, Claudia Isabel
Hamet, María Fernanda
Peláez, Angela M.L.
Soria, Mario
Zapata, Roberto A.
author_facet Franco, Mariana C.
Soria, Mario
Federico, Francisco Javier
Zapata, Roberto A.
Hamet, María Fernanda
Gallinger, Claudia Isabel
De Antoni, Graciela L.
Peláez, Angela M.L.
Basiouni, Shereen
Bueno, Dante Javier
author_sort Franco, Mariana C.
collection INTA Digital
description Kefir contains lactic acid bacteria and yeasts, which are involved in fermentation and contribute to its probiotic effects. The simultaneous supplementation feeding of antibiotics and probiotics could serve as a way to replace antibiotic growth promoters (AGP) gradually. So, this study was conducted to evaluate the effect of the microbial fraction of kefir and four strains of Lactiplantibacillus plantarum subsp. plantarum (MFKLP) with promising in vitro probiotic properties, applied in drinking water, and AGP on different parameters in broiler chickens for 28 days. Compared to AGP alone, the MFKLP-AGP consumption decreased the percentage of liver lipids by 24% and 34% at 21 and 28 days of age, respectively. Furthermore, it modified the percentage of some types of leukocytes. It decreased the percentage of eosinophil from 1.8% to 0.2% at day 7, decreased the percentage of lymphocytes, and increased the percentage of heterophils and the heterophil/lymphocyte ratio from 72.8% to 58.6%, 21.6% to 34.8%, and 0.3 to 0.6 at 21 days of age, respectively, and increased the percentage of monocytes from 4.7% to 5.4% at 28 days of age. It also increased the percentage of monocytes at 28 days of age and decreased the crypt depth, and increased the villus height to crypt depth ratio and microbial community diversity at days 21 and 28. The concurrent supplementation of MFKLP and AGP is beneficial for gut and liver health, and this supports the case for continuing research into the use of MFKLP for developing health-promoting functional feed for poultry.
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institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
language Inglés
publishDate 2025
publishDateRange 2025
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spelling INTA231852025-07-28T15:07:07Z Simultaneous supplementation of the microbial fraction of kefir containing Lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance, gut microbiota, and health parameters in broiler chickens Franco, Mariana C. Soria, Mario Federico, Francisco Javier Zapata, Roberto A. Hamet, María Fernanda Gallinger, Claudia Isabel De Antoni, Graciela L. Peláez, Angela M.L. Basiouni, Shereen Bueno, Dante Javier Pollo de Engorde Suplementos Flora Microbiana Bacteria Acidoláctica Broiler Chickens Supplements Lactobacillus plantarum Kefir Microbial Flora Lactic Acid Bacteria Lactiplantibacillus plantarum Microbiota Kefir contains lactic acid bacteria and yeasts, which are involved in fermentation and contribute to its probiotic effects. The simultaneous supplementation feeding of antibiotics and probiotics could serve as a way to replace antibiotic growth promoters (AGP) gradually. So, this study was conducted to evaluate the effect of the microbial fraction of kefir and four strains of Lactiplantibacillus plantarum subsp. plantarum (MFKLP) with promising in vitro probiotic properties, applied in drinking water, and AGP on different parameters in broiler chickens for 28 days. Compared to AGP alone, the MFKLP-AGP consumption decreased the percentage of liver lipids by 24% and 34% at 21 and 28 days of age, respectively. Furthermore, it modified the percentage of some types of leukocytes. It decreased the percentage of eosinophil from 1.8% to 0.2% at day 7, decreased the percentage of lymphocytes, and increased the percentage of heterophils and the heterophil/lymphocyte ratio from 72.8% to 58.6%, 21.6% to 34.8%, and 0.3 to 0.6 at 21 days of age, respectively, and increased the percentage of monocytes from 4.7% to 5.4% at 28 days of age. It also increased the percentage of monocytes at 28 days of age and decreased the crypt depth, and increased the villus height to crypt depth ratio and microbial community diversity at days 21 and 28. The concurrent supplementation of MFKLP and AGP is beneficial for gut and liver health, and this supports the case for continuing research into the use of MFKLP for developing health-promoting functional feed for poultry. EEA Concepción del Uruguay Fil: Franco, Mariana C. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Franco, Mariana C. Universidad Nacional de La Plata; Argentina Fil: Franco, Mariana C. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; Argentina Fil: Soria, Mario Alberto. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Concepción del Uruguay; Argentina Fil: Federico, Francisco Javier. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Concepción del Uruguay; Argentina Fil: Zapata, Roberto A. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; Argentina Fil: Hamet, María Fernanda. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; Argentina Fil: Gallinger, Claudia Isabel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Concepción del Uruguay; Argentina Fil: De Antoni, Graciela L. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; Argentina Fil: De Antoni, Graciela L. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina Fil: De Antoni, Graciela L. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina Fil: Peláez, Angela M.L. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; Argentina Fil: Basiouni, Shereen. Johannes-Gutenberg University. Institute of Molecular Physiology. Cilia Cell Biology; Alemania Fil: Bueno, Dante Javier. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Concepción del Uruguay; Argentina Fil: Bueno, Dante Javier. Universidad Autónoma de Entre Ríos: Sede Basavilbaso. Facultad de Ciencia y Tecnología; Argentina 2025-07-28T14:35:24Z 2025-07-28T14:35:24Z 2025-07 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/23185 https://gmpc-akademie.de/articles/gjvr/single/275 2703-1322 https://doi.org/10.51585/gjvr.2025.2.0136 eng info:eu-repograntAgreement/INTA/2023-PD-L06-I115, Resistencia Antimicrobiana y desarrollo de alternativas que minimicen el uso de antibióticos y antiparasitarios para una produccion animal mas sustentable info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf German Multidisciplinary Publishing Center (GMPC) German Journal of Veterinary Research 5 (2): 73-89. (2025)
spellingShingle Pollo de Engorde
Suplementos
Flora Microbiana
Bacteria Acidoláctica
Broiler Chickens
Supplements
Lactobacillus plantarum
Kefir
Microbial Flora
Lactic Acid Bacteria
Lactiplantibacillus plantarum
Microbiota
Franco, Mariana C.
Soria, Mario
Federico, Francisco Javier
Zapata, Roberto A.
Hamet, María Fernanda
Gallinger, Claudia Isabel
De Antoni, Graciela L.
Peláez, Angela M.L.
Basiouni, Shereen
Bueno, Dante Javier
Simultaneous supplementation of the microbial fraction of kefir containing Lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance, gut microbiota, and health parameters in broiler chickens
title Simultaneous supplementation of the microbial fraction of kefir containing Lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance, gut microbiota, and health parameters in broiler chickens
title_full Simultaneous supplementation of the microbial fraction of kefir containing Lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance, gut microbiota, and health parameters in broiler chickens
title_fullStr Simultaneous supplementation of the microbial fraction of kefir containing Lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance, gut microbiota, and health parameters in broiler chickens
title_full_unstemmed Simultaneous supplementation of the microbial fraction of kefir containing Lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance, gut microbiota, and health parameters in broiler chickens
title_short Simultaneous supplementation of the microbial fraction of kefir containing Lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance, gut microbiota, and health parameters in broiler chickens
title_sort simultaneous supplementation of the microbial fraction of kefir containing lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance gut microbiota and health parameters in broiler chickens
topic Pollo de Engorde
Suplementos
Flora Microbiana
Bacteria Acidoláctica
Broiler Chickens
Supplements
Lactobacillus plantarum
Kefir
Microbial Flora
Lactic Acid Bacteria
Lactiplantibacillus plantarum
Microbiota
url http://hdl.handle.net/20.500.12123/23185
https://gmpc-akademie.de/articles/gjvr/single/275
https://doi.org/10.51585/gjvr.2025.2.0136
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