Oxidative and inflammatory status, daily weight gain, intake and feed efficiency on natural congenitally Neospora caninum infected dairy calves

This study explored the effect of Neospora caninum infection on oxidative and inflammatory status in newborn dairy calves and the relationship between antibody levels in dairy cows and congenital transmission. The study involved 59 cow-calf pairs from a dairy herd in Mar y Sierras Basin, Argentina....

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Autores principales: Miqueo, Evangelina, Cruz, Micaela Solange, Moore, Prando Dadin, Campero, Lucia Maria
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: Elsevier 2025
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/23017
https://www.sciencedirect.com/science/article/abs/pii/S0304401725001414
https://doi.org/10.1016/j.vetpar.2025.110530
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author Miqueo, Evangelina
Cruz, Micaela Solange
Moore, Prando Dadin
Campero, Lucia Maria
author_browse Campero, Lucia Maria
Cruz, Micaela Solange
Miqueo, Evangelina
Moore, Prando Dadin
author_facet Miqueo, Evangelina
Cruz, Micaela Solange
Moore, Prando Dadin
Campero, Lucia Maria
author_sort Miqueo, Evangelina
collection INTA Digital
description This study explored the effect of Neospora caninum infection on oxidative and inflammatory status in newborn dairy calves and the relationship between antibody levels in dairy cows and congenital transmission. The study involved 59 cow-calf pairs from a dairy herd in Mar y Sierras Basin, Argentina. Calf performance metrics (total intake, daily weight gain, feed efficiency, and fecal consistency) were recorded. Serum samples from cows were collected prepartum, and from calves at birth (pre-colostrum), 7, 14, and 63 days of birth to assess N. caninum antibodies and oxidative status. No differences in total intake, daily weight gain, feed efficiency, or fecal score were observed between N. caninum infected and non-infected calves. Similarly, total antioxidant status, thiobarbituric acid reactive substances, and haptoglobin levels did not differ between groups. Among the 59 cows evaluated, 17 tested seropositive for N. caninum. Of these, 15 gave birth to N. caninum seropositive calves, corresponding to a vertical transmission rate of 88.2 %. Among these cows, higher relative index percentage (RIPC) values were associated with successful vertical transmission (mean RIPC 69.8 vs. 7.8; p = 0.01). Congenitally infected calves also had higher RIPC values compared to those that seroconverted postnatally (mean RIPC 32 vs 17.4; p = 0.02). The absence of oxidative stress differences suggests parasite adaptation in congenitally infected calves without clinical signs. This study highlights a substantial transplacental transmission linked to higher RICP in seropositive cows and limited exposure to N. caninum during the artificial rearing. Results emphasize two factors: higher antibody levels correlated with congenital transmission and the absence of horizontal transmission during dairy calf rearing.
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institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
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spelling INTA230172025-07-14T14:01:04Z Oxidative and inflammatory status, daily weight gain, intake and feed efficiency on natural congenitally Neospora caninum infected dairy calves Miqueo, Evangelina Cruz, Micaela Solange Moore, Prando Dadin Campero, Lucia Maria Neosporosis Terneros Estrés de Oxidativo Trasmisión Vertical Transmisión Horizontal Calves Oxidative Stress Vertical Transmission Horizontal Transmission Dairy Cattle Neospora caninum Ganado de Leche This study explored the effect of Neospora caninum infection on oxidative and inflammatory status in newborn dairy calves and the relationship between antibody levels in dairy cows and congenital transmission. The study involved 59 cow-calf pairs from a dairy herd in Mar y Sierras Basin, Argentina. Calf performance metrics (total intake, daily weight gain, feed efficiency, and fecal consistency) were recorded. Serum samples from cows were collected prepartum, and from calves at birth (pre-colostrum), 7, 14, and 63 days of birth to assess N. caninum antibodies and oxidative status. No differences in total intake, daily weight gain, feed efficiency, or fecal score were observed between N. caninum infected and non-infected calves. Similarly, total antioxidant status, thiobarbituric acid reactive substances, and haptoglobin levels did not differ between groups. Among the 59 cows evaluated, 17 tested seropositive for N. caninum. Of these, 15 gave birth to N. caninum seropositive calves, corresponding to a vertical transmission rate of 88.2 %. Among these cows, higher relative index percentage (RIPC) values were associated with successful vertical transmission (mean RIPC 69.8 vs. 7.8; p = 0.01). Congenitally infected calves also had higher RIPC values compared to those that seroconverted postnatally (mean RIPC 32 vs 17.4; p = 0.02). The absence of oxidative stress differences suggests parasite adaptation in congenitally infected calves without clinical signs. This study highlights a substantial transplacental transmission linked to higher RICP in seropositive cows and limited exposure to N. caninum during the artificial rearing. Results emphasize two factors: higher antibody levels correlated with congenital transmission and the absence of horizontal transmission during dairy calf rearing. EEA Balcarce Fil: Miqueo, Evangelina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina Fil: Cruz, Micaela Solange. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina Fil: Moore, Dadin Prando. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina Fil: Moore, Dadin Prando. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina Fil: Campero, Lucía María. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina 2025-07-14T13:48:36Z 2025-07-14T13:48:36Z 2025-08 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/23017 https://www.sciencedirect.com/science/article/abs/pii/S0304401725001414 1873-2550 (Online) 0304-4017 (Print) https://doi.org/10.1016/j.vetpar.2025.110530 eng info:eu-repograntAgreement/INTA/2019-PD-E5-I103-001, Desarrollo de tecnologías diagnósticas y estudios epidemiológicos para el control de enfermedades que afectan la producción animal y la salud pública info:eu-repo/semantics/restrictedAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Elsevier Veterinary Parasitology 338 : 110530 (August 2025)
spellingShingle Neosporosis
Terneros
Estrés de Oxidativo
Trasmisión Vertical
Transmisión Horizontal
Calves
Oxidative Stress
Vertical Transmission
Horizontal Transmission
Dairy Cattle
Neospora caninum
Ganado de Leche
Miqueo, Evangelina
Cruz, Micaela Solange
Moore, Prando Dadin
Campero, Lucia Maria
Oxidative and inflammatory status, daily weight gain, intake and feed efficiency on natural congenitally Neospora caninum infected dairy calves
title Oxidative and inflammatory status, daily weight gain, intake and feed efficiency on natural congenitally Neospora caninum infected dairy calves
title_full Oxidative and inflammatory status, daily weight gain, intake and feed efficiency on natural congenitally Neospora caninum infected dairy calves
title_fullStr Oxidative and inflammatory status, daily weight gain, intake and feed efficiency on natural congenitally Neospora caninum infected dairy calves
title_full_unstemmed Oxidative and inflammatory status, daily weight gain, intake and feed efficiency on natural congenitally Neospora caninum infected dairy calves
title_short Oxidative and inflammatory status, daily weight gain, intake and feed efficiency on natural congenitally Neospora caninum infected dairy calves
title_sort oxidative and inflammatory status daily weight gain intake and feed efficiency on natural congenitally neospora caninum infected dairy calves
topic Neosporosis
Terneros
Estrés de Oxidativo
Trasmisión Vertical
Transmisión Horizontal
Calves
Oxidative Stress
Vertical Transmission
Horizontal Transmission
Dairy Cattle
Neospora caninum
Ganado de Leche
url http://hdl.handle.net/20.500.12123/23017
https://www.sciencedirect.com/science/article/abs/pii/S0304401725001414
https://doi.org/10.1016/j.vetpar.2025.110530
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