Grapevine holobiome metatranscriptomics provides a glimpse into the wood mycovirome

Given the agronomic and economic importance of viticulture, grapevine has been shown to host the largest number of viruses among plants to date. Nevertheless, studies assessing the grapevine-associated holobiont remain scarce. In this context, the viral component of this ecological niche is understu...

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Main Authors: Debat, Humberto Julio, Paolinelli, Marcos, Escoriaza, Maria Georgina, Garcia Lampasona, Sandra Claudia, Gomez Talquenca, Gonzalo, Bejerman, Nicolas Esteban
Format: Artículo
Language:Inglés
Published: Elsevier 2025
Subjects:
Online Access:http://hdl.handle.net/20.500.12123/22834
https://www.sciencedirect.com/science/article/pii/S004268222500217X
https://doi.org/10.1016/j.virol.2025.110604
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author Debat, Humberto Julio
Paolinelli, Marcos
Escoriaza, Maria Georgina
Garcia Lampasona, Sandra Claudia
Gomez Talquenca, Gonzalo
Bejerman, Nicolas Esteban
author_browse Bejerman, Nicolas Esteban
Debat, Humberto Julio
Escoriaza, Maria Georgina
Garcia Lampasona, Sandra Claudia
Gomez Talquenca, Gonzalo
Paolinelli, Marcos
author_facet Debat, Humberto Julio
Paolinelli, Marcos
Escoriaza, Maria Georgina
Garcia Lampasona, Sandra Claudia
Gomez Talquenca, Gonzalo
Bejerman, Nicolas Esteban
author_sort Debat, Humberto Julio
collection INTA Digital
description Given the agronomic and economic importance of viticulture, grapevine has been shown to host the largest number of viruses among plants to date. Nevertheless, studies assessing the grapevine-associated holobiont remain scarce. In this context, the viral component of this ecological niche is understudied. In this work, through metatranscriptomics of wood samples from individual grapevines that were either healthy or exhibited symptoms of grapevine trunk disease from Argentina, we provide a glimpse into the wood linked virome. Virus discovery from high-throughput sequencing data resulted in the identification and reconstruction of 123 novel virus sequences. Genetic and phylogenetic insights suggest that these sequences correspond to 78 novel virus species. Structural and functional annotation of the viruses showed a great diversity of genomic organizations, with the presence of dsRNA, ssRNA( ) and ssRNA(+) viruses belonging to more than 15 virus families. Some highly divergent viruses resembling narnaviruses, ophioviruses, deltaflexiviruses and bunyaviruses could be accommodated within new genera or even new virus families. The differential detection and variable RNA levels across samples suggest complex dynamics and prevalence patterns of those novel viruses. The viral profile described here provides a first insight into the multifaceted South American grapevine wood holobiont mycovirome.
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institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
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spelling INTA228342025-06-30T17:05:15Z Grapevine holobiome metatranscriptomics provides a glimpse into the wood mycovirome Debat, Humberto Julio Paolinelli, Marcos Escoriaza, Maria Georgina Garcia Lampasona, Sandra Claudia Gomez Talquenca, Gonzalo Bejerman, Nicolas Esteban Vid Grapevines Transcriptomics Transcriptómica Mycovirome Holobiont Metatranscriptomics Virus Diversity Viral Taxonomy Given the agronomic and economic importance of viticulture, grapevine has been shown to host the largest number of viruses among plants to date. Nevertheless, studies assessing the grapevine-associated holobiont remain scarce. In this context, the viral component of this ecological niche is understudied. In this work, through metatranscriptomics of wood samples from individual grapevines that were either healthy or exhibited symptoms of grapevine trunk disease from Argentina, we provide a glimpse into the wood linked virome. Virus discovery from high-throughput sequencing data resulted in the identification and reconstruction of 123 novel virus sequences. Genetic and phylogenetic insights suggest that these sequences correspond to 78 novel virus species. Structural and functional annotation of the viruses showed a great diversity of genomic organizations, with the presence of dsRNA, ssRNA( ) and ssRNA(+) viruses belonging to more than 15 virus families. Some highly divergent viruses resembling narnaviruses, ophioviruses, deltaflexiviruses and bunyaviruses could be accommodated within new genera or even new virus families. The differential detection and variable RNA levels across samples suggest complex dynamics and prevalence patterns of those novel viruses. The viral profile described here provides a first insight into the multifaceted South American grapevine wood holobiont mycovirome. Instituto de Patología Vegetal Fil: Debat, Humberto Julio. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; Argentina Fil: Debat, Humberto Julio. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Fitopatología y Modelización Agrícola (UFyMA); Argentina Fil: Paolinelli, Marcos. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Mendoza; Argentina Fil: Escoriaza, Maria Georgina. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Mendoza; Argentina Fil: Garcia Lampasona, Sandra Claudia.Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Mendoza; Argentina Fil: Garcia Lampasona, Sandra Claudia. Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias. Instituto de Biología Agrícola de Mendoza (IBAM); Argentina. Consejo Nacional de Investigaciones Científicas y Técnica. Instituto de Biología Agrícola de Mendoza (IBAM); Argentina Fil: Gomez Talquenca, Gonzalo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Mendoza; Argentina Fil: Bejerman, Nicolas Esteban. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; Argentina Fil: Bejerman, Nicolas Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Fitopatología y Modelización Agrícola (UFyMA); Argentina 2025-06-30T16:50:05Z 2025-06-30T16:50:05Z 2025-06-20 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/22834 https://www.sciencedirect.com/science/article/pii/S004268222500217X 0042-6822 https://doi.org/10.1016/j.virol.2025.110604 eng info:eu-repograntAgreement/INTA/2023-PD-L01-I085, Identificación y caracterización funcional de genes interés biotecnológico para la sostenibilidad productiva y ambiental info:eu-repo/semantics/restrictedAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Elsevier Virology 610 : 110604 (September 2025)
spellingShingle Vid
Grapevines
Transcriptomics
Transcriptómica
Mycovirome
Holobiont
Metatranscriptomics
Virus Diversity
Viral Taxonomy
Debat, Humberto Julio
Paolinelli, Marcos
Escoriaza, Maria Georgina
Garcia Lampasona, Sandra Claudia
Gomez Talquenca, Gonzalo
Bejerman, Nicolas Esteban
Grapevine holobiome metatranscriptomics provides a glimpse into the wood mycovirome
title Grapevine holobiome metatranscriptomics provides a glimpse into the wood mycovirome
title_full Grapevine holobiome metatranscriptomics provides a glimpse into the wood mycovirome
title_fullStr Grapevine holobiome metatranscriptomics provides a glimpse into the wood mycovirome
title_full_unstemmed Grapevine holobiome metatranscriptomics provides a glimpse into the wood mycovirome
title_short Grapevine holobiome metatranscriptomics provides a glimpse into the wood mycovirome
title_sort grapevine holobiome metatranscriptomics provides a glimpse into the wood mycovirome
topic Vid
Grapevines
Transcriptomics
Transcriptómica
Mycovirome
Holobiont
Metatranscriptomics
Virus Diversity
Viral Taxonomy
url http://hdl.handle.net/20.500.12123/22834
https://www.sciencedirect.com/science/article/pii/S004268222500217X
https://doi.org/10.1016/j.virol.2025.110604
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