Focus on translational research from arabidopsis to crop plants and beyond

Over the past 4 decades, substantial research efforts in plant science worldwide have focused on the model system Arabidopsis thaliana (Provart et al. 2015). Many of us have dedicated years to the study of Arabidopsis, motivated by the notion that our findings will yield advancements in agriculture...

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Autores principales: Roeder, Adrienne H.K., Argueso, Cristiana T., Williams, Mary, Auge, Gabriela, Li, Xin, Strader, Lucia, Uauy, Cristobal, Wu, Shuang
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: Oxford University Press 2025
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/22691
https://academic.oup.com/plcell/article/37/5/koaf119/8133187
https://doi.org/10.1093/plcell/koaf119
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author Roeder, Adrienne H.K.
Argueso, Cristiana T.
Williams, Mary
Auge, Gabriela
Li, Xin
Strader, Lucia
Uauy, Cristobal
Wu, Shuang
author_browse Argueso, Cristiana T.
Auge, Gabriela
Li, Xin
Roeder, Adrienne H.K.
Strader, Lucia
Uauy, Cristobal
Williams, Mary
Wu, Shuang
author_facet Roeder, Adrienne H.K.
Argueso, Cristiana T.
Williams, Mary
Auge, Gabriela
Li, Xin
Strader, Lucia
Uauy, Cristobal
Wu, Shuang
author_sort Roeder, Adrienne H.K.
collection INTA Digital
description Over the past 4 decades, substantial research efforts in plant science worldwide have focused on the model system Arabidopsis thaliana (Provart et al. 2015). Many of us have dedicated years to the study of Arabidopsis, motivated by the notion that our findings will yield advancements in agriculture and natural ecosystems. Considering translation holistically as the gene functions, pathways, and technologies discovered and developed in Arabidopsis that inform our understanding of other plants, Arabidopsis has had a powerful influence. In particular, the annotation of plant genomes heavily relies on the gene functions elucidated in Arabidopsis (Whitt et al. 2020; Wimalanathan and Lawrence-Dill 2021; Fattel et al. 2022). Many technologies and techniques pioneered in Arabidopsis have been successfully translated to crops and other plant species (Yaschenko et al. 2025). Remarkably, discoveries in Arabidopsis and other plants have also contributed significantly to biomedical research (Jones et al. 2008; Strader et al. 2025). For example, the auxin degron system is widely used to degrade proteins on demand in animal/human cells by adding auxin to the cell cultures (Nishimura et al. 2009). Further, Arabidopsis research aimed at understanding plant adaptation to changing environments, with the goal of predicting evolutionary trajectories, holds the potential to guide conservation efforts in the face of climate change (Hancock et al. 2011; Assmann 2013; Wilczek et al. 2014; Arana and Picó 2025). However, we must ask the question of whether the features that make Arabidopsis a powerful model (i.e. its compact genome, ease of transformation, small size, and inexpensive growth) remain exclusive to this plant and whether the lessons learned from peculiar features of Arabidopsis can be extrapolated to plants we cultivate or those living in natural ecosystems, either directly or indirectly. Twenty-five years after the publication of the Arabidopsis genome sequence in 2000 (AGI 2000), it is a good time to reflect on the impact of research in Arabidopsis in this focus issue.
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institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
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spelling INTA226912025-06-13T16:46:42Z Focus on translational research from arabidopsis to crop plants and beyond Roeder, Adrienne H.K. Argueso, Cristiana T. Williams, Mary Auge, Gabriela Li, Xin Strader, Lucia Uauy, Cristobal Wu, Shuang Arabidopsis Plants Genes Planta Gen Over the past 4 decades, substantial research efforts in plant science worldwide have focused on the model system Arabidopsis thaliana (Provart et al. 2015). Many of us have dedicated years to the study of Arabidopsis, motivated by the notion that our findings will yield advancements in agriculture and natural ecosystems. Considering translation holistically as the gene functions, pathways, and technologies discovered and developed in Arabidopsis that inform our understanding of other plants, Arabidopsis has had a powerful influence. In particular, the annotation of plant genomes heavily relies on the gene functions elucidated in Arabidopsis (Whitt et al. 2020; Wimalanathan and Lawrence-Dill 2021; Fattel et al. 2022). Many technologies and techniques pioneered in Arabidopsis have been successfully translated to crops and other plant species (Yaschenko et al. 2025). Remarkably, discoveries in Arabidopsis and other plants have also contributed significantly to biomedical research (Jones et al. 2008; Strader et al. 2025). For example, the auxin degron system is widely used to degrade proteins on demand in animal/human cells by adding auxin to the cell cultures (Nishimura et al. 2009). Further, Arabidopsis research aimed at understanding plant adaptation to changing environments, with the goal of predicting evolutionary trajectories, holds the potential to guide conservation efforts in the face of climate change (Hancock et al. 2011; Assmann 2013; Wilczek et al. 2014; Arana and Picó 2025). However, we must ask the question of whether the features that make Arabidopsis a powerful model (i.e. its compact genome, ease of transformation, small size, and inexpensive growth) remain exclusive to this plant and whether the lessons learned from peculiar features of Arabidopsis can be extrapolated to plants we cultivate or those living in natural ecosystems, either directly or indirectly. Twenty-five years after the publication of the Arabidopsis genome sequence in 2000 (AGI 2000), it is a good time to reflect on the impact of research in Arabidopsis in this focus issue. Instituto de Biotecnología Fil: Roeder, Adrienne H. K. Cornell University. Section of Plant Biology and Weill Institute for Cell and Molecular Biology. School of Integrative Plant Science; Estados Unidos Fil: Argueso, Cristiana T. Colorado State University. Department of Agricultural Biology; Estados Unidos Fil: Williams, Mary. American Society of Plant Biology; Estados Unidos Fil: Auge, Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Auge, Gabriela. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular (IABIMO); Argentina Fil: Li, Xin. University of British Columbia. Michael Smith Laboratories; Canadá Fil: Strader, Lucia. Duke University. Department of Biology; Estados Unidos Fil: Uauy, Cristobal. Norwich Research Park. John Innes Centre; Reino Unido Fil: Wu, Shuang. Fujian Agriculture and Forestry University. College of Horticulture. State Key Laboratory of Agricultural and Forestry Biosecurity; China 2025-06-13T16:42:37Z 2025-06-13T16:42:37Z 2025-05 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/22691 https://academic.oup.com/plcell/article/37/5/koaf119/8133187 1532-298X https://doi.org/10.1093/plcell/koaf119 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Oxford University Press The Plant Cell 37 (5) : koaf119 (May 2025)
spellingShingle Arabidopsis
Plants
Genes
Planta
Gen
Roeder, Adrienne H.K.
Argueso, Cristiana T.
Williams, Mary
Auge, Gabriela
Li, Xin
Strader, Lucia
Uauy, Cristobal
Wu, Shuang
Focus on translational research from arabidopsis to crop plants and beyond
title Focus on translational research from arabidopsis to crop plants and beyond
title_full Focus on translational research from arabidopsis to crop plants and beyond
title_fullStr Focus on translational research from arabidopsis to crop plants and beyond
title_full_unstemmed Focus on translational research from arabidopsis to crop plants and beyond
title_short Focus on translational research from arabidopsis to crop plants and beyond
title_sort focus on translational research from arabidopsis to crop plants and beyond
topic Arabidopsis
Plants
Genes
Planta
Gen
url http://hdl.handle.net/20.500.12123/22691
https://academic.oup.com/plcell/article/37/5/koaf119/8133187
https://doi.org/10.1093/plcell/koaf119
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