Enzymes for production of whey protein hydrolysates and other value‑added products
Whey is a byproduct of dairy industries, the aqueous portion which separates from cheese during the coagulation of milk. It represents approximately 85–95% of milk’s volume and retains much of its nutrients, including functional proteins and peptides, lipids, lactose, minerals, and vitamins. Due...
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| Format: | info:ar-repo/semantics/artículo |
| Language: | Inglés |
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Springer
2025
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| Online Access: | http://hdl.handle.net/20.500.12123/22218 https://doi.org/10.1007/s00253-024-13117-2 |
| _version_ | 1855038535622459392 |
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| author | Irazoqui, Jose Matias Santiago, Gonzalo Manuel Mainez, María Esperanza Amadio, Ariel Eberhardt, María Florencia |
| author_browse | Amadio, Ariel Eberhardt, María Florencia Irazoqui, Jose Matias Mainez, María Esperanza Santiago, Gonzalo Manuel |
| author_facet | Irazoqui, Jose Matias Santiago, Gonzalo Manuel Mainez, María Esperanza Amadio, Ariel Eberhardt, María Florencia |
| author_sort | Irazoqui, Jose Matias |
| collection | INTA Digital |
| description | Whey is a byproduct of dairy industries, the aqueous portion which separates from cheese during the coagulation of milk.
It represents approximately 85–95% of milk’s volume and retains much of its nutrients, including functional proteins and
peptides, lipids, lactose, minerals, and vitamins. Due to its composition, mainly proteins and lactose, it can be considered
a raw material for value-added products. Whey-derived products are often used to supplement food, as they have shown
several physiological efects on the body. Whey protein hydrolysates are reported to have diferent activities, including anti hypertensive, antioxidant, antithrombotic, opioid, antimicrobial, cytomodulatory, and immuno-modulatory. On the other
hand, galactooligosaccharides obtained from lactose can be used as prebiotic for benefcial microorganisms for the human
gastrointestinal tract. All these compounds can be obtained through physicochemical, microbial, or enzymatic treatments.
Particularly, enzymatic processes have the advantage of being highly selective, more stable than chemical transformations,
and less polluting, making that the global enzyme market grow at accelerated rates. The sources and diferent products associ ated with the most used enzymes are particularly highlighted in this review. Moreover, we discuss metagenomics as a tool to
identify novel proteolytic enzymes, from both cultivable and uncultivable microorganisms, which are expected to have new
interesting activities. Finally enzymes for the transformation of whey sugar are reviewed. In this sense, carbozymes with
ß-galactosidase activity are capable of lactose hydrolysis, to obtain free monomers, and transgalactosylation for prebiotics
production. |
| format | info:ar-repo/semantics/artículo |
| id | INTA22218 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | Springer |
| publisherStr | Springer |
| record_format | dspace |
| spelling | INTA222182025-05-09T13:42:04Z Enzymes for production of whey protein hydrolysates and other value‑added products Irazoqui, Jose Matias Santiago, Gonzalo Manuel Mainez, María Esperanza Amadio, Ariel Eberhardt, María Florencia Enzymes Galactosidases Whey Whey protein Enzima Galactosidasa Lactosuero Proteínas de suero de leche Biopeptides Galactooligosaccharides Whey proteases Whey is a byproduct of dairy industries, the aqueous portion which separates from cheese during the coagulation of milk. It represents approximately 85–95% of milk’s volume and retains much of its nutrients, including functional proteins and peptides, lipids, lactose, minerals, and vitamins. Due to its composition, mainly proteins and lactose, it can be considered a raw material for value-added products. Whey-derived products are often used to supplement food, as they have shown several physiological efects on the body. Whey protein hydrolysates are reported to have diferent activities, including anti hypertensive, antioxidant, antithrombotic, opioid, antimicrobial, cytomodulatory, and immuno-modulatory. On the other hand, galactooligosaccharides obtained from lactose can be used as prebiotic for benefcial microorganisms for the human gastrointestinal tract. All these compounds can be obtained through physicochemical, microbial, or enzymatic treatments. Particularly, enzymatic processes have the advantage of being highly selective, more stable than chemical transformations, and less polluting, making that the global enzyme market grow at accelerated rates. The sources and diferent products associ ated with the most used enzymes are particularly highlighted in this review. Moreover, we discuss metagenomics as a tool to identify novel proteolytic enzymes, from both cultivable and uncultivable microorganisms, which are expected to have new interesting activities. Finally enzymes for the transformation of whey sugar are reviewed. In this sense, carbozymes with ß-galactosidase activity are capable of lactose hydrolysis, to obtain free monomers, and transgalactosylation for prebiotics production. EEA Rafaela Fil: Irazoqui, Jose Matias. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela. Instituto de Investigación de la Cadena Láctea (IDICAL); Argentina Fil: Irazoqui, Jose Matias. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Instituto de Investigación de la Cadena Láctea (IDICAL); Argentina Fil: Santiago, Gonzalo Manuel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela. Instituto de Investigación de la Cadena Láctea (IDICAL); Argentina Fil: Santiago, Gonzalo Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Instituto de Investigación de la Cadena Láctea (IDICAL); Argentina Fil: Mainez, María Esperanza. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela. Instituto de Investigación de la Cadena Láctea (IDICAL); Argentina Fil: Mainez, María Esperanza. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Instituto de Investigación de la Cadena Láctea (IDICAL); Argentina Fil: Amadio, Ariel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela. Instituto de Investigación de la Cadena Láctea (IDICAL); Argentina Fil: Amadio, Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Instituto de Investigación de la Cadena Láctea (IDICAL); Argentina Fil: Eberhardt, Maria Florencia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela. Instituto de Investigación de la Cadena Láctea (IDICAL); Argentina Fil: Eberhardt, Maria Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Instituto de Investigación de la Cadena Láctea (IDICAL); Argentina 2025-05-09T13:29:43Z 2025-05-09T13:29:43Z 2024 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/22218 1432-0614 0175-7598 https://doi.org/10.1007/s00253-024-13117-2 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Springer Applied Microbiology and Biotechnology 108 : 354 (2024) |
| spellingShingle | Enzymes Galactosidases Whey Whey protein Enzima Galactosidasa Lactosuero Proteínas de suero de leche Biopeptides Galactooligosaccharides Whey proteases Irazoqui, Jose Matias Santiago, Gonzalo Manuel Mainez, María Esperanza Amadio, Ariel Eberhardt, María Florencia Enzymes for production of whey protein hydrolysates and other value‑added products |
| title | Enzymes for production of whey protein hydrolysates and other value‑added products |
| title_full | Enzymes for production of whey protein hydrolysates and other value‑added products |
| title_fullStr | Enzymes for production of whey protein hydrolysates and other value‑added products |
| title_full_unstemmed | Enzymes for production of whey protein hydrolysates and other value‑added products |
| title_short | Enzymes for production of whey protein hydrolysates and other value‑added products |
| title_sort | enzymes for production of whey protein hydrolysates and other value added products |
| topic | Enzymes Galactosidases Whey Whey protein Enzima Galactosidasa Lactosuero Proteínas de suero de leche Biopeptides Galactooligosaccharides Whey proteases |
| url | http://hdl.handle.net/20.500.12123/22218 https://doi.org/10.1007/s00253-024-13117-2 |
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