Detoxification response in honey bee larvae exposed to agricultural intensification
Honey bee Apis mellifera colonies located in agroecosystems are exposed to pesticides and more fragmented habitats. The resources that bees obtain in these environments may be exposed to agrochemicals, which can accumulate in their colonies and be distributed among their nest mates. Hives placed in...
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| Format: | info:ar-repo/semantics/artículo |
| Language: | Inglés |
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Elsevier
2025
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.12123/22181 https://www.sciencedirect.com/science/article/abs/pii/S0048969725010253 https://doi.org/10.1016/j.scitotenv.2025.179388 |
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| author | Macri, Ivana Noelia Latorre Estivalis, Jose M. Nery, Denise Derguy, María Rosa Cristos, Diego Sebastian Zavala, Jorge Alberto Farina, Walter Marcelo |
| author_browse | Cristos, Diego Sebastian Derguy, María Rosa Farina, Walter Marcelo Latorre Estivalis, Jose M. Macri, Ivana Noelia Nery, Denise Zavala, Jorge Alberto |
| author_facet | Macri, Ivana Noelia Latorre Estivalis, Jose M. Nery, Denise Derguy, María Rosa Cristos, Diego Sebastian Zavala, Jorge Alberto Farina, Walter Marcelo |
| author_sort | Macri, Ivana Noelia |
| collection | INTA Digital |
| description | Honey bee Apis mellifera colonies located in agroecosystems are exposed to pesticides and more fragmented habitats. The resources that bees obtain in these environments may be exposed to agrochemicals, which can accumulate in their colonies and be distributed among their nest mates. Hives placed in an agricultural setting located in the region of the Argentine Pampas were studied. Changes in the expression levels of insect cytochrome P450s, enzymes involved in the detoxification of xenobiotics, and the presence of pesticides in hive products at different times of crop management were evaluated. Our results showed that CYP6AS2 and CYP6AS4 expression in honey bee larvae increased significantly after crop flowering and pesticide application. Furthermore, residues of the herbicides atrazine and glyphosate, and the insecticide chlorantraniliprole were found in beeswax and honey samples collected from the same beehives, and their concentrations correlated with the expression profiles of CYP6AS2, CYP6AS3 and CYP9BD1. These results underscore the potential risks of pesticides exposure to larval development, highlighting the need to mitigate agrochemical use in agricultural landscapes to safeguard honey bee colonies. |
| format | info:ar-repo/semantics/artículo |
| id | INTA22181 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | INTA221812025-05-07T13:10:26Z Detoxification response in honey bee larvae exposed to agricultural intensification Macri, Ivana Noelia Latorre Estivalis, Jose M. Nery, Denise Derguy, María Rosa Cristos, Diego Sebastian Zavala, Jorge Alberto Farina, Walter Marcelo Abeja Melífera Agricultura Intensificación Desintoxicación Honey Bees Apis mellifera Agriculture Intensification Detoxification Agricultural Intensification Honey bee Apis mellifera colonies located in agroecosystems are exposed to pesticides and more fragmented habitats. The resources that bees obtain in these environments may be exposed to agrochemicals, which can accumulate in their colonies and be distributed among their nest mates. Hives placed in an agricultural setting located in the region of the Argentine Pampas were studied. Changes in the expression levels of insect cytochrome P450s, enzymes involved in the detoxification of xenobiotics, and the presence of pesticides in hive products at different times of crop management were evaluated. Our results showed that CYP6AS2 and CYP6AS4 expression in honey bee larvae increased significantly after crop flowering and pesticide application. Furthermore, residues of the herbicides atrazine and glyphosate, and the insecticide chlorantraniliprole were found in beeswax and honey samples collected from the same beehives, and their concentrations correlated with the expression profiles of CYP6AS2, CYP6AS3 and CYP9BD1. These results underscore the potential risks of pesticides exposure to larval development, highlighting the need to mitigate agrochemical use in agricultural landscapes to safeguard honey bee colonies. Instituto de Ingeniería Rural Fil: Macri, Ivana Noelia. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental. Laboratorio de Insectos Sociales; Argentina Fil: Macri, Ivana Noelia. Universidad de Buenos Aires. Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE); Argentina Fil: Macri, Ivana Noelia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE); Argentina Fil: Macri, Ivana Noelia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Ingeniería Rural; Argentina. Fil: Latorre Estivalis, José M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental. Laboratorio de Insectos Sociales; Argentina Fil: Latorre Estivalis, José M. Universidad de Buenos Aires. Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE); Argentina. Fil: Latorre Estivalis, José M. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE); Argentina. Fil: Nery, Denise. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental. Laboratorio de Insectos Sociales; Argentina Fil: Nery, Denise. Universidad de Buenos Aires. Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE); Argentina Fil: Nery, Denise. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE); Argentina Fil: Derguy, María Rosa. Universidad Nacional de La Plata. Laboratorio de Investigaciones de Sistemas Ecológicos y Ambientales (LISEA); Argentina Fil: Cristos, Diego Sebastian. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Tecnología de Alimentos; Argentina. Fil: Zavala, Jorge A. Universidad de Buenos Aires. Facultad de Agronomía. Cátedra de Bioquímica and Cátedra de Zoología Agrícola; Argentina Fil: Zavala, Jorge A. Universidad de Buenos Aires. Instituto de Investigaciones en Biociencias Agrícolas y Ambientales (INBA); Argentina. Fil: Zavala, Jorge A. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Biociencias Agrícolas y Ambientales (INBA); Argentina Fil: Farina, Walter M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental. Laboratorio de Insectos Sociales; Argentina Fil: Farina, Walter M. Universidad de Buenos Aires. Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE); Argentina Fil: Farina, Walter M. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE); Argentina 2025-05-07T13:07:31Z 2025-05-07T13:07:31Z 2025-05 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/22181 https://www.sciencedirect.com/science/article/abs/pii/S0048969725010253 0048-9697 1879-1026 https://doi.org/10.1016/j.scitotenv.2025.179388 eng info:eu-repograntAgreement/INTA/2019-PE-E1-I017-001, Desarrollo del sector apícola organizado, sustentable y competitivo info:eu-repo/semantics/restrictedAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Elsevier Science of The Total Environment 978 : 179388. (May 2025) |
| spellingShingle | Abeja Melífera Agricultura Intensificación Desintoxicación Honey Bees Apis mellifera Agriculture Intensification Detoxification Agricultural Intensification Macri, Ivana Noelia Latorre Estivalis, Jose M. Nery, Denise Derguy, María Rosa Cristos, Diego Sebastian Zavala, Jorge Alberto Farina, Walter Marcelo Detoxification response in honey bee larvae exposed to agricultural intensification |
| title | Detoxification response in honey bee larvae exposed to agricultural intensification |
| title_full | Detoxification response in honey bee larvae exposed to agricultural intensification |
| title_fullStr | Detoxification response in honey bee larvae exposed to agricultural intensification |
| title_full_unstemmed | Detoxification response in honey bee larvae exposed to agricultural intensification |
| title_short | Detoxification response in honey bee larvae exposed to agricultural intensification |
| title_sort | detoxification response in honey bee larvae exposed to agricultural intensification |
| topic | Abeja Melífera Agricultura Intensificación Desintoxicación Honey Bees Apis mellifera Agriculture Intensification Detoxification Agricultural Intensification |
| url | http://hdl.handle.net/20.500.12123/22181 https://www.sciencedirect.com/science/article/abs/pii/S0048969725010253 https://doi.org/10.1016/j.scitotenv.2025.179388 |
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