Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina : Clinical, histopathological and molecular studies
Sarcoptic mange, caused by the mite Sarcoptes scabiei, is a highly contagious and potentially fatal skin disease that affects a wide range of mammals, including South American Camelids (SAC). Although the presence of mange has been described in vicuñas and llamas in northwestern Argentina, there are...
| Autores principales: | , , , , , , , , |
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| Formato: | info:ar-repo/semantics/artículo |
| Lenguaje: | Inglés |
| Publicado: |
Elsevier
2025
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12123/22146 https://www.sciencedirect.com/science/article/pii/S2213224425000276 https://doi.org/10.1016/j.ijppaw.2025.101062 |
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| author | Sosa, Fabiana Evangelina Anello, Melina Ferreyra, Hebe del Valle Medina Vallejo, Diego M. Micheloud, Juan Francisco Borsetti, Hugo M. Hernández, Nancy Florin-Christensen, Monica Romero, Sandra Raquel |
| author_browse | Anello, Melina Borsetti, Hugo M. Ferreyra, Hebe del Valle Florin-Christensen, Monica Hernández, Nancy Medina Vallejo, Diego M. Micheloud, Juan Francisco Romero, Sandra Raquel Sosa, Fabiana Evangelina |
| author_facet | Sosa, Fabiana Evangelina Anello, Melina Ferreyra, Hebe del Valle Medina Vallejo, Diego M. Micheloud, Juan Francisco Borsetti, Hugo M. Hernández, Nancy Florin-Christensen, Monica Romero, Sandra Raquel |
| author_sort | Sosa, Fabiana Evangelina |
| collection | INTA Digital |
| description | Sarcoptic mange, caused by the mite Sarcoptes scabiei, is a highly contagious and potentially fatal skin disease that affects a wide range of mammals, including South American Camelids (SAC). Although the presence of mange has been described in vicuñas and llamas in northwestern Argentina, there are no previous records documenting its presence in guanacos (Lama guanicoe) of this region. We here describe a case of S. scabiei in a free-ranging guanaco in the Department of Tilcara, Jujuy Province. The animal presented alopecic, erythematous and hyperkeratotic lesions with abundant crusts in the ventral region of the body and limbs. Histopathology revealed periadnexal dermatitis with inflammatory infiltrate, severe hyperemia, orthokeratotic and parakeratotic epidermal hyperplasia, and stratum corneum thickening. The etiological agent was identified as S. scabiei by microscopic examination of adult mites. This result was confirmed by sequencing of a cytochrome oxidase subunit I gene fragment, that showed 100 % identity with sequences of isolates from SAC and other mammals. Genotyping of three mites isolated from different parts of the guanaco's body using a set of ten microsatellite markers indicated the infection with a single genetic variant that showed a similar profile to those found in S. scabiei isolates from vicuñas and llamas of the same region. However, genetic differences with guanaco isolates from midwestern Argentina were observed. This work presents the first record of sarcoptic mange in a guanaco in Jujuy Province and in the northwestern region of Argentina, as well as the molecular characterization of the etiological agent. The case highlights an uncertain scenario regarding the health situation of the guanaco population in this region, which is small, fragmented, and locally categorized as endangered. Epidemiological surveillance programs for guanacos and further research on the impact of sarcoptic mange on the conservation of this species are needed. |
| format | info:ar-repo/semantics/artículo |
| id | INTA22146 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | INTA221462025-05-05T10:07:59Z Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina : Clinical, histopathological and molecular studies Sosa, Fabiana Evangelina Anello, Melina Ferreyra, Hebe del Valle Medina Vallejo, Diego M. Micheloud, Juan Francisco Borsetti, Hugo M. Hernández, Nancy Florin-Christensen, Monica Romero, Sandra Raquel Guanacos Sarcoptic Mange Mites Genotyping Resource Conservation Lama guanicoe Guanaco Sarna Sarcóptica Ácaros Genotipado Conservación de los Recursos Argentina Sarcoptic mange, caused by the mite Sarcoptes scabiei, is a highly contagious and potentially fatal skin disease that affects a wide range of mammals, including South American Camelids (SAC). Although the presence of mange has been described in vicuñas and llamas in northwestern Argentina, there are no previous records documenting its presence in guanacos (Lama guanicoe) of this region. We here describe a case of S. scabiei in a free-ranging guanaco in the Department of Tilcara, Jujuy Province. The animal presented alopecic, erythematous and hyperkeratotic lesions with abundant crusts in the ventral region of the body and limbs. Histopathology revealed periadnexal dermatitis with inflammatory infiltrate, severe hyperemia, orthokeratotic and parakeratotic epidermal hyperplasia, and stratum corneum thickening. The etiological agent was identified as S. scabiei by microscopic examination of adult mites. This result was confirmed by sequencing of a cytochrome oxidase subunit I gene fragment, that showed 100 % identity with sequences of isolates from SAC and other mammals. Genotyping of three mites isolated from different parts of the guanaco's body using a set of ten microsatellite markers indicated the infection with a single genetic variant that showed a similar profile to those found in S. scabiei isolates from vicuñas and llamas of the same region. However, genetic differences with guanaco isolates from midwestern Argentina were observed. This work presents the first record of sarcoptic mange in a guanaco in Jujuy Province and in the northwestern region of Argentina, as well as the molecular characterization of the etiological agent. The case highlights an uncertain scenario regarding the health situation of the guanaco population in this region, which is small, fragmented, and locally categorized as endangered. Epidemiological surveillance programs for guanacos and further research on the impact of sarcoptic mange on the conservation of this species are needed. Instituto de Patobiología Fil: Sosa, Fabiana Evangelina. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación y Desarrollo Tecnológico para la Agricultura Familiar Región NOA; Argentina Fil: Sosa, Fabiana Evangelina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Anello, Melina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Anello, Melina. Universidad Nacional del Comahue. Instituto de Investigaciones en Biodiversidad y Medioambiente. Grupo de Investigaciones en Ecología y Fisiología de Fauna Silvestre; Argentina Fil: Ferreyra, Hebe del Valle. Administracion de Parques Nacionales; Argentina Fil: Medina Vallejo, Diego M. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación Animal del Chaco Semiárido. Área de Sanidad Animal; Argentina Fil: Micheloud, Juan Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Micheloud, Juan Francisco. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación Animal del Chaco Semiárido. Área de Sanidad Animal; Argentina Fil: Borsetti, Hugo M. Universidad Nacional de Jujuy. Instituto de Estudios Celulares, Genéticos y Moleculares (ICeGeM); Argentina Fil: Hernández, Nancy. Universidad Nacional de Jujuy. Instituto de Estudios Celulares, Genéticos y Moleculares (ICeGeM); Argentina Fil: Hernández, Nancy. Instituto de Ecorregiones Andinas (INECOA); Argentina Fil: Hernández, Nancy. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Florin-Christensen, Monica. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Florin-Christensen, Monica. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología Veterinaria; Argentina Fil: Romero, Sandra Raquel. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación y Desarrollo Tecnológico para la Agricultura Familiar Región NOA; Argentina 2025-05-05T09:54:10Z 2025-05-05T09:54:10Z 2025-08 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/22146 https://www.sciencedirect.com/science/article/pii/S2213224425000276 2213-2244 https://doi.org/10.1016/j.ijppaw.2025.101062 eng info:eu-repograntAgreement/INTA/2023-PD-L06-I114, Desarrollo y aplicación de métodos diagnósticos y epidemiológicos para la producción pecuaria sustentable y agroalimentaria en humanos con foco en Una Salud info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Elsevier International Journal for Parasitology: Parasites and Wildlife 27 : 101062 (August 2025) |
| spellingShingle | Guanacos Sarcoptic Mange Mites Genotyping Resource Conservation Lama guanicoe Guanaco Sarna Sarcóptica Ácaros Genotipado Conservación de los Recursos Argentina Sosa, Fabiana Evangelina Anello, Melina Ferreyra, Hebe del Valle Medina Vallejo, Diego M. Micheloud, Juan Francisco Borsetti, Hugo M. Hernández, Nancy Florin-Christensen, Monica Romero, Sandra Raquel Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina : Clinical, histopathological and molecular studies |
| title | Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina : Clinical, histopathological and molecular studies |
| title_full | Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina : Clinical, histopathological and molecular studies |
| title_fullStr | Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina : Clinical, histopathological and molecular studies |
| title_full_unstemmed | Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina : Clinical, histopathological and molecular studies |
| title_short | Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina : Clinical, histopathological and molecular studies |
| title_sort | sarcoptic mange in a guanaco lama guanicoe of northwestern argentina clinical histopathological and molecular studies |
| topic | Guanacos Sarcoptic Mange Mites Genotyping Resource Conservation Lama guanicoe Guanaco Sarna Sarcóptica Ácaros Genotipado Conservación de los Recursos Argentina |
| url | http://hdl.handle.net/20.500.12123/22146 https://www.sciencedirect.com/science/article/pii/S2213224425000276 https://doi.org/10.1016/j.ijppaw.2025.101062 |
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