AHAS Trp574Leu substitution in Raphanus sativus L.: screening, enzyme activity and fitness cost

BACKGROUND: Feral radish (Raphanus sativus L.) is a problematic weed that has become resistant to acetohydroxyacid synthase (AHAS) inhibitor herbicides due to the Trp574Leu mutation. An AHAS gene mutation that causes herbicide resistance may have negative pleiotropic effects on plant fitness. This s...

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Autores principales: Vercellino, Roman Boris, Pandolfo, Claudio Ezequiel, Breccia, Gabriela, Cantamutto, Miguel Angel, Presotto, Alejandro Daniel
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: 2018
Materias:
Acceso en línea:https://onlinelibrary.wiley.com/doi/abs/10.1002/ps.4849
http://hdl.handle.net/20.500.12123/2180
https://doi.org/10.1002/ps.4849
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author Vercellino, Roman Boris
Pandolfo, Claudio Ezequiel
Breccia, Gabriela
Cantamutto, Miguel Angel
Presotto, Alejandro Daniel
author_browse Breccia, Gabriela
Cantamutto, Miguel Angel
Pandolfo, Claudio Ezequiel
Presotto, Alejandro Daniel
Vercellino, Roman Boris
author_facet Vercellino, Roman Boris
Pandolfo, Claudio Ezequiel
Breccia, Gabriela
Cantamutto, Miguel Angel
Presotto, Alejandro Daniel
author_sort Vercellino, Roman Boris
collection INTA Digital
description BACKGROUND: Feral radish (Raphanus sativus L.) is a problematic weed that has become resistant to acetohydroxyacid synthase (AHAS) inhibitor herbicides due to the Trp574Leu mutation. An AHAS gene mutation that causes herbicide resistance may have negative pleiotropic effects on plant fitness. This study reports the effects of the Trp574Leu mutation on AHAS activity and reproductive traits of R. sativus. RESULTS: Eight of 17 feral radish accessions presented individuals resistant to metsulfuron‐methyl at 0.5% to >90.0% and all the resistant individuals analyzed showed the Trp574Leu mutation. Without herbicide selection, the AHAS activity was 3.2‐fold higher in the susceptible accession than in the resistant one. The resistant accession was >9000‐fold more resistant to metsulfuron‐methyl and imazethapyr than the susceptible accession. Under low intraspecific competition during two growing seasons, AHAS‐resistant feral radish accessions showed 22–38% and 21–47% lower seed numbers and yield per plant than the susceptible accession. CONCLUSION: This is the first report of fitness cost associated with the AHAS Trp574Leu mutation in R. sativus populations. This fitness cost could reduce frequency of the resistant allele without herbicide selection
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institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
language Inglés
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spelling INTA21802024-04-30T11:51:20Z AHAS Trp574Leu substitution in Raphanus sativus L.: screening, enzyme activity and fitness cost Vercellino, Roman Boris Pandolfo, Claudio Ezequiel Breccia, Gabriela Cantamutto, Miguel Angel Presotto, Alejandro Daniel Raphanus sativus Actividad Enzimática Enzyme Activity Genetics Mutation Genética Mutación BACKGROUND: Feral radish (Raphanus sativus L.) is a problematic weed that has become resistant to acetohydroxyacid synthase (AHAS) inhibitor herbicides due to the Trp574Leu mutation. An AHAS gene mutation that causes herbicide resistance may have negative pleiotropic effects on plant fitness. This study reports the effects of the Trp574Leu mutation on AHAS activity and reproductive traits of R. sativus. RESULTS: Eight of 17 feral radish accessions presented individuals resistant to metsulfuron‐methyl at 0.5% to >90.0% and all the resistant individuals analyzed showed the Trp574Leu mutation. Without herbicide selection, the AHAS activity was 3.2‐fold higher in the susceptible accession than in the resistant one. The resistant accession was >9000‐fold more resistant to metsulfuron‐methyl and imazethapyr than the susceptible accession. Under low intraspecific competition during two growing seasons, AHAS‐resistant feral radish accessions showed 22–38% and 21–47% lower seed numbers and yield per plant than the susceptible accession. CONCLUSION: This is the first report of fitness cost associated with the AHAS Trp574Leu mutation in R. sativus populations. This fitness cost could reduce frequency of the resistant allele without herbicide selection EEA Hilario Ascasubi Fil: Vercellino, Roman B. Universidad Nacional del Sur. Departamento de Agronomía; Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Bahía Blanca. Centro de Recursos Naturales Renovables de la Zona Semiárida; Argentina Fil: Pandolfo, Claudio Ezequiel. Universidad Nacional del Sur. Departamento de Agronomía; Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Bahía Blanca. Centro de Recursos Naturales Renovables de la Zona Semiárida; Argentina Fil: Breccia, Gabriela. Universidad Nacional de Rosario. Facultad de Ciencias Agrarias. Instituto de Investigaciones en Ciencias Agrarias de Rosario; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Cantamutto, Miguel Angel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Hilario Ascasubi; Argentina Fil: Presotto, Alejandro Daniel. Universidad Nacional del Sur. Departamento de Agronomía; Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Bahía Blanca. Centro de Recursos Naturales Renovables de la Zona Semiárida; Argentina 2018-04-05T15:50:41Z 2018-04-05T15:50:41Z 2018-07 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://onlinelibrary.wiley.com/doi/abs/10.1002/ps.4849 http://hdl.handle.net/20.500.12123/2180 1526-498X 1526-4998 https://doi.org/10.1002/ps.4849 eng info:eu-repo/semantics/restrictedAccess application/pdf Pest management science 74 (7):1600-1607. (2018 Jul.)
spellingShingle Raphanus sativus
Actividad Enzimática
Enzyme Activity
Genetics
Mutation
Genética
Mutación
Vercellino, Roman Boris
Pandolfo, Claudio Ezequiel
Breccia, Gabriela
Cantamutto, Miguel Angel
Presotto, Alejandro Daniel
AHAS Trp574Leu substitution in Raphanus sativus L.: screening, enzyme activity and fitness cost
title AHAS Trp574Leu substitution in Raphanus sativus L.: screening, enzyme activity and fitness cost
title_full AHAS Trp574Leu substitution in Raphanus sativus L.: screening, enzyme activity and fitness cost
title_fullStr AHAS Trp574Leu substitution in Raphanus sativus L.: screening, enzyme activity and fitness cost
title_full_unstemmed AHAS Trp574Leu substitution in Raphanus sativus L.: screening, enzyme activity and fitness cost
title_short AHAS Trp574Leu substitution in Raphanus sativus L.: screening, enzyme activity and fitness cost
title_sort ahas trp574leu substitution in raphanus sativus l screening enzyme activity and fitness cost
topic Raphanus sativus
Actividad Enzimática
Enzyme Activity
Genetics
Mutation
Genética
Mutación
url https://onlinelibrary.wiley.com/doi/abs/10.1002/ps.4849
http://hdl.handle.net/20.500.12123/2180
https://doi.org/10.1002/ps.4849
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