Evaluation of GnRH- versus estradiol-based protocols for ovulation synchronization in postpartum Bos taurus grazing beef cows submitted to fixed-time artificial insemination

This study compared the effect of a 7-day estradiol- and a 7-day GnRH-based FTAI protocol versus a presynchronized GnRH-based FTAI protocol (7 & 7 GnRH) on pregnancy per AI (P/AI) in multiparous postpartum Angus cows. Cows were blocked according to presence/absence of a CL, body condition score, and...

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Autores principales: Ferre, Luis Bernardo, Cerviño, Maria Natalia, Jaeschke, Julian, Itterman, Maximiliano, McLean, Jaime, Aragon, Agustin, Fernández, Manuel, Villa, Matías, Formia, Néstor, Jaureguiberry, Maria, Rearte, Ramiro, Kjelland, Michael E., Colazo, Marcos G., Thomas, Jordan M., De la Sota, Rodolfo Luzbel
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: Elsevier 2025
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/20800
https://www.sciencedirect.com/science/article/abs/pii/S0093691X24004618
https://doi.org/10.1016/j.theriogenology.2024.11.008
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author Ferre, Luis Bernardo
Cerviño, Maria Natalia
Jaeschke, Julian
Itterman, Maximiliano
McLean, Jaime
Aragon, Agustin
Fernández, Manuel
Villa, Matías
Formia, Néstor
Jaureguiberry, Maria
Rearte, Ramiro
Kjelland, Michael E.
Colazo, Marcos G.
Thomas, Jordan M.
De la Sota, Rodolfo Luzbel
author_browse Aragon, Agustin
Cerviño, Maria Natalia
Colazo, Marcos G.
De la Sota, Rodolfo Luzbel
Fernández, Manuel
Ferre, Luis Bernardo
Formia, Néstor
Itterman, Maximiliano
Jaeschke, Julian
Jaureguiberry, Maria
Kjelland, Michael E.
McLean, Jaime
Rearte, Ramiro
Thomas, Jordan M.
Villa, Matías
author_facet Ferre, Luis Bernardo
Cerviño, Maria Natalia
Jaeschke, Julian
Itterman, Maximiliano
McLean, Jaime
Aragon, Agustin
Fernández, Manuel
Villa, Matías
Formia, Néstor
Jaureguiberry, Maria
Rearte, Ramiro
Kjelland, Michael E.
Colazo, Marcos G.
Thomas, Jordan M.
De la Sota, Rodolfo Luzbel
author_sort Ferre, Luis Bernardo
collection INTA Digital
description This study compared the effect of a 7-day estradiol- and a 7-day GnRH-based FTAI protocol versus a presynchronized GnRH-based FTAI protocol (7 & 7 GnRH) on pregnancy per AI (P/AI) in multiparous postpartum Angus cows. Cows were blocked according to presence/absence of a CL, body condition score, and days postpartum and assigned randomly to one of three treatments: I) 7-day EB (n = 368), estradiol benzoate (EB) and intravaginal progesterone-(P4)-releasing device (IVPD) on Day −10, prostaglandin F2α (PG), equine chorionic gonadotropin (eCG) and estradiol cypionate (ECP) at IVPD removal on Day −3 with FTAI done on Day −1 (54 ± 2 h after IVPD removal); II) 7-day GnRH (n = 367), GnRH at IVPD insertion on Day −10, PG and eCG at IVPD removal on Day −3 with GnRH and FTAI on Day 0 (66 ± 2 h after IVPD removal); and III) 7 & 7 GnRH (n = 361), PG at IVPD insertion on Day −17, GnRH on Day −10, IVPD removal, PG and eCG on Day −3 with GnRH and FTAI on Day 0 (66 ± 2 h after IVPD removal). Preovulatory follicle diameter, corpus luteum (CL) presence, CL area, and P4 concentration were determined at IVPD removal, as well as estrus expression at FTAI and P/AI between 35 and 40 days after FTAI. Plasma P4 concentrations at IVPD removal were greater (P < 0.05) in cows subjected to the 7-day GnRH or 7 & 7 GnRH protocols and a greater number of cows (P < 0.05) had at least one CL at IVPD removal compared to cows subjected to the 7-day EB protocol. However, the 7 & 7 GnRH protocol resulted in more cows with two CLs at IVPD removal compared to the other two protocols. Moreover, cows synchronized with the 7 & 7 GnRH protocol had larger preovulatory follicles (P < 0.05) and larger CL area at IVPD removal (P < 0.05), and a greater rate of estrus expression before FTAI (P < 0.05) than cows synchronized with the 7-day EB, whereas those variables were intermediate in cows synchronized with the 7-day GnRH. Pregnancy per AI was greater (P < 0.05) in cows treated with the 7 & 7 GnRH (63.5 %) treatment compared to the 7-day EB (51.4 %) and the 7-day GnRH (51.3 %) protocols. In summary, the 7 & 7 GnRH protocol enhanced circulating P4 before IVPD removal, increased estrus expression rate before FTAI, and improved P/AI in postpartum Bos taurus grazing beef cows.
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institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
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spelling INTA208002025-01-02T10:37:50Z Evaluation of GnRH- versus estradiol-based protocols for ovulation synchronization in postpartum Bos taurus grazing beef cows submitted to fixed-time artificial insemination Ferre, Luis Bernardo Cerviño, Maria Natalia Jaeschke, Julian Itterman, Maximiliano McLean, Jaime Aragon, Agustin Fernández, Manuel Villa, Matías Formia, Néstor Jaureguiberry, Maria Rearte, Ramiro Kjelland, Michael E. Colazo, Marcos G. Thomas, Jordan M. De la Sota, Rodolfo Luzbel Bos taurus Beef Cattle Oestrus Synchronization Perinatal Period Estradiol GnRH Artificial Insemination Ganado de Carne Sincronización del Celo Período Perinatal Inseminación Artificial This study compared the effect of a 7-day estradiol- and a 7-day GnRH-based FTAI protocol versus a presynchronized GnRH-based FTAI protocol (7 & 7 GnRH) on pregnancy per AI (P/AI) in multiparous postpartum Angus cows. Cows were blocked according to presence/absence of a CL, body condition score, and days postpartum and assigned randomly to one of three treatments: I) 7-day EB (n = 368), estradiol benzoate (EB) and intravaginal progesterone-(P4)-releasing device (IVPD) on Day −10, prostaglandin F2α (PG), equine chorionic gonadotropin (eCG) and estradiol cypionate (ECP) at IVPD removal on Day −3 with FTAI done on Day −1 (54 ± 2 h after IVPD removal); II) 7-day GnRH (n = 367), GnRH at IVPD insertion on Day −10, PG and eCG at IVPD removal on Day −3 with GnRH and FTAI on Day 0 (66 ± 2 h after IVPD removal); and III) 7 & 7 GnRH (n = 361), PG at IVPD insertion on Day −17, GnRH on Day −10, IVPD removal, PG and eCG on Day −3 with GnRH and FTAI on Day 0 (66 ± 2 h after IVPD removal). Preovulatory follicle diameter, corpus luteum (CL) presence, CL area, and P4 concentration were determined at IVPD removal, as well as estrus expression at FTAI and P/AI between 35 and 40 days after FTAI. Plasma P4 concentrations at IVPD removal were greater (P < 0.05) in cows subjected to the 7-day GnRH or 7 & 7 GnRH protocols and a greater number of cows (P < 0.05) had at least one CL at IVPD removal compared to cows subjected to the 7-day EB protocol. However, the 7 & 7 GnRH protocol resulted in more cows with two CLs at IVPD removal compared to the other two protocols. Moreover, cows synchronized with the 7 & 7 GnRH protocol had larger preovulatory follicles (P < 0.05) and larger CL area at IVPD removal (P < 0.05), and a greater rate of estrus expression before FTAI (P < 0.05) than cows synchronized with the 7-day EB, whereas those variables were intermediate in cows synchronized with the 7-day GnRH. Pregnancy per AI was greater (P < 0.05) in cows treated with the 7 & 7 GnRH (63.5 %) treatment compared to the 7-day EB (51.4 %) and the 7-day GnRH (51.3 %) protocols. In summary, the 7 & 7 GnRH protocol enhanced circulating P4 before IVPD removal, increased estrus expression rate before FTAI, and improved P/AI in postpartum Bos taurus grazing beef cows. EEA Barrow Fil: Ferre, Luis Bernardo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Barrow; Argentina Fil: Cerviño, Maria Natalia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Jaeschke, J. Biogénesis Bagó; Argentina. Fil: Itterman, Maximiliano. Biogénesis Bagó; Argentina. Fil: McLean, Jaime. Estudio McLean Producción & Reproducción Bovina; Argentina Fil: Aragon, Agustin. Estudio McLean Producción & Reproducción Bovina; Argentina Fil: Fernández, Manuel. Estudio McLean Producción & Reproducción Bovina; Argentina Fil: Villa, Matías. Estudio McLean Producción & Reproducción Bovina; Argentina Fil: Formia, Néstor. Universidad Nacional de la Plata. Facultad de Ciencias Veterinarias. Instituto de Investigaciones en Reproducción Animal (INIRA); Argentina Fil: Jaureguiberry, Maria. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Jaureguiberry, Maria. Universidad Nacional de la Plata. Facultad de Ciencias Veterinarias. Instituto de Investigaciones en Reproducción Animal (INIRA); Argentina Fil: Rearte, Ramiro. Universidad Nacional de la Plata. Facultad de Ciencias Veterinarias. Instituto de Investigaciones en Reproducción Animal (INIRA); Argentina Fil: Kjelland, M.E. Mayville State University; Estados Unidos Fil: Colazo, Marcos G. Leduc Farm Animal Hospital; Canadá Fil: Thomas, J. University of Missouri. Division of Animal Sciences; Estados Unidos Fil: de la Sota, R.L. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: de la Sota, R.L. Universidad Nacional de la Plata. Facultad de Ciencias Veterinarias. Instituto de Investigaciones en Reproducción Animal (INIRA); Argentina 2025-01-02T10:34:52Z 2025-01-02T10:34:52Z 2025-02 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/20800 https://www.sciencedirect.com/science/article/abs/pii/S0093691X24004618 0093-691X 1879-3231 https://doi.org/10.1016/j.theriogenology.2024.11.008 eng info:eu-repo/semantics/restrictedAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Elsevier Theriogenology 233 : 1-7. (February 2025)
spellingShingle Bos taurus
Beef Cattle
Oestrus Synchronization
Perinatal Period
Estradiol
GnRH
Artificial Insemination
Ganado de Carne
Sincronización del Celo
Período Perinatal
Inseminación Artificial
Ferre, Luis Bernardo
Cerviño, Maria Natalia
Jaeschke, Julian
Itterman, Maximiliano
McLean, Jaime
Aragon, Agustin
Fernández, Manuel
Villa, Matías
Formia, Néstor
Jaureguiberry, Maria
Rearte, Ramiro
Kjelland, Michael E.
Colazo, Marcos G.
Thomas, Jordan M.
De la Sota, Rodolfo Luzbel
Evaluation of GnRH- versus estradiol-based protocols for ovulation synchronization in postpartum Bos taurus grazing beef cows submitted to fixed-time artificial insemination
title Evaluation of GnRH- versus estradiol-based protocols for ovulation synchronization in postpartum Bos taurus grazing beef cows submitted to fixed-time artificial insemination
title_full Evaluation of GnRH- versus estradiol-based protocols for ovulation synchronization in postpartum Bos taurus grazing beef cows submitted to fixed-time artificial insemination
title_fullStr Evaluation of GnRH- versus estradiol-based protocols for ovulation synchronization in postpartum Bos taurus grazing beef cows submitted to fixed-time artificial insemination
title_full_unstemmed Evaluation of GnRH- versus estradiol-based protocols for ovulation synchronization in postpartum Bos taurus grazing beef cows submitted to fixed-time artificial insemination
title_short Evaluation of GnRH- versus estradiol-based protocols for ovulation synchronization in postpartum Bos taurus grazing beef cows submitted to fixed-time artificial insemination
title_sort evaluation of gnrh versus estradiol based protocols for ovulation synchronization in postpartum bos taurus grazing beef cows submitted to fixed time artificial insemination
topic Bos taurus
Beef Cattle
Oestrus Synchronization
Perinatal Period
Estradiol
GnRH
Artificial Insemination
Ganado de Carne
Sincronización del Celo
Período Perinatal
Inseminación Artificial
url http://hdl.handle.net/20.500.12123/20800
https://www.sciencedirect.com/science/article/abs/pii/S0093691X24004618
https://doi.org/10.1016/j.theriogenology.2024.11.008
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