Molecular identification of Sarcocystis aucheniae in the wild South American camelid Vicugna vicugna

Vicuñas (Vicugna vicugna) are wild South American camelids (SACs) protected by law in Argentina, and information on pathogens that infect them is scarce. In this study, an adult vicuña found dead in the province of Salta was examined, and evidence of infection by Sarcocystis sp. protozoans was sough...

Descripción completa

Detalles Bibliográficos
Autores principales: Wieser, Sara Nathaly, Cafrune Wierna, María Mercedes, Romero, Sandra Raquel, Schnittger, Leonhard, Florin-Christensen, Monica
Formato: Artículo
Lenguaje:Inglés
Publicado: Springer 2024
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/19074
https://link.springer.com/article/10.1007/s11259-024-10491-0
https://doi.org/10.1007/s11259-024-10491-0
_version_ 1855486301222993920
author Wieser, Sara Nathaly
Cafrune Wierna, María Mercedes
Romero, Sandra Raquel
Schnittger, Leonhard
Florin-Christensen, Monica
author_browse Cafrune Wierna, María Mercedes
Florin-Christensen, Monica
Romero, Sandra Raquel
Schnittger, Leonhard
Wieser, Sara Nathaly
author_facet Wieser, Sara Nathaly
Cafrune Wierna, María Mercedes
Romero, Sandra Raquel
Schnittger, Leonhard
Florin-Christensen, Monica
author_sort Wieser, Sara Nathaly
collection INTA Digital
description Vicuñas (Vicugna vicugna) are wild South American camelids (SACs) protected by law in Argentina, and information on pathogens that infect them is scarce. In this study, an adult vicuña found dead in the province of Salta was examined, and evidence of infection by Sarcocystis sp. protozoans was sought. Infection of skeletal muscles by S. aucheniae, with the production of macroscopic sarcocysts, a disease known as SAC sarcocystosis, has been described in the other three SACs - llamas, alpacas, and guanacos - but its occurrence in vicuñas has so far remained unknown. In the analyzed individual, many macroscopic cysts compatible with S. aucheniae were found upon necropsy in the muscular tissue of the neck and diaphragm. Analysis of 18 S rRNA and cytochrome c oxidase subunit 1 (cox-1) gene sequences by BLAST searches and construction of phylogenetic trees demonstrated that the etiological agent was S. aucheniae. Our results show for the first time that vicuñas act as intermediate hosts in the life cycle of this parasite. In addition, this study provides the first cox-1 sequences for S. aucheniae isolates from the four SAC species acting as intermediate hosts and suggests that this marker could be useful for genotypification of this parasite species. The impact of SAC sarcocystosis on the health, well-being, and fitness of vicuñas, and the relevance of vicuña infections in the epidemiology of S. auchaniae, remain to be elucidated.
format Artículo
id INTA19074
institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
language Inglés
publishDate 2024
publishDateRange 2024
publishDateSort 2024
publisher Springer
publisherStr Springer
record_format dspace
spelling INTA190742024-08-23T10:10:16Z Molecular identification of Sarcocystis aucheniae in the wild South American camelid Vicugna vicugna Wieser, Sara Nathaly Cafrune Wierna, María Mercedes Romero, Sandra Raquel Schnittger, Leonhard Florin-Christensen, Monica Sarcocystosis Camelids Vicugna vicugna Ribosomal RNA Sarcocistosis Camélidos ARN Ribosomial Sarcocystis aucheniae Vicuñas (Vicugna vicugna) are wild South American camelids (SACs) protected by law in Argentina, and information on pathogens that infect them is scarce. In this study, an adult vicuña found dead in the province of Salta was examined, and evidence of infection by Sarcocystis sp. protozoans was sought. Infection of skeletal muscles by S. aucheniae, with the production of macroscopic sarcocysts, a disease known as SAC sarcocystosis, has been described in the other three SACs - llamas, alpacas, and guanacos - but its occurrence in vicuñas has so far remained unknown. In the analyzed individual, many macroscopic cysts compatible with S. aucheniae were found upon necropsy in the muscular tissue of the neck and diaphragm. Analysis of 18 S rRNA and cytochrome c oxidase subunit 1 (cox-1) gene sequences by BLAST searches and construction of phylogenetic trees demonstrated that the etiological agent was S. aucheniae. Our results show for the first time that vicuñas act as intermediate hosts in the life cycle of this parasite. In addition, this study provides the first cox-1 sequences for S. aucheniae isolates from the four SAC species acting as intermediate hosts and suggests that this marker could be useful for genotypification of this parasite species. The impact of SAC sarcocystosis on the health, well-being, and fitness of vicuñas, and the relevance of vicuña infections in the epidemiology of S. auchaniae, remain to be elucidated. Instituto de Patobiología Fil: Wieser, Sarah Nathaly. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología Veterinaria; Argentina Fil: Wieser, Sarah Nathaly. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Cafrune Wierna, Marí­a Mercedes. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación Animal del Chaco Semiárido; Argentina Fil: Romero, Sandra Raquel. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación y Desarrollo Tecnológico para la Agricultura Familiar Región NOA; Argentina Fil: Schnittger, Leonhard. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología Veterinaria; Argentina Fil: Schnittger, Leonhard. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Florin-Christensen, Monica. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología Veterinaria; Argentina Fil: Florin-Christensen, Monica. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina 2024-08-23T10:01:11Z 2024-08-23T10:01:11Z 2024-08 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/19074 https://link.springer.com/article/10.1007/s11259-024-10491-0 1573-7446 https://doi.org/10.1007/s11259-024-10491-0 eng info:eu-repograntAgreement/INTA/2023-PD-L06-I114, Desarrollo y aplicación de métodos diagnósticos y epidemiológicos para la producción pecuaria sustentable y agroalimentaria en humanos con foco en Una Salud info:eu-repograntAgreement/INTA/2019-RIST-E5-I111-001, Laboratorios de Diagnóstico Veterinario info:eu-repo/semantics/restrictedAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Springer Veterinary Research Communications : 1-7 (Published: 09 August 2024)
spellingShingle Sarcocystosis
Camelids
Vicugna vicugna
Ribosomal RNA
Sarcocistosis
Camélidos
ARN Ribosomial
Sarcocystis aucheniae
Wieser, Sara Nathaly
Cafrune Wierna, María Mercedes
Romero, Sandra Raquel
Schnittger, Leonhard
Florin-Christensen, Monica
Molecular identification of Sarcocystis aucheniae in the wild South American camelid Vicugna vicugna
title Molecular identification of Sarcocystis aucheniae in the wild South American camelid Vicugna vicugna
title_full Molecular identification of Sarcocystis aucheniae in the wild South American camelid Vicugna vicugna
title_fullStr Molecular identification of Sarcocystis aucheniae in the wild South American camelid Vicugna vicugna
title_full_unstemmed Molecular identification of Sarcocystis aucheniae in the wild South American camelid Vicugna vicugna
title_short Molecular identification of Sarcocystis aucheniae in the wild South American camelid Vicugna vicugna
title_sort molecular identification of sarcocystis aucheniae in the wild south american camelid vicugna vicugna
topic Sarcocystosis
Camelids
Vicugna vicugna
Ribosomal RNA
Sarcocistosis
Camélidos
ARN Ribosomial
Sarcocystis aucheniae
url http://hdl.handle.net/20.500.12123/19074
https://link.springer.com/article/10.1007/s11259-024-10491-0
https://doi.org/10.1007/s11259-024-10491-0
work_keys_str_mv AT wiesersaranathaly molecularidentificationofsarcocystisaucheniaeinthewildsouthamericancamelidvicugnavicugna
AT cafrunewiernamariamercedes molecularidentificationofsarcocystisaucheniaeinthewildsouthamericancamelidvicugnavicugna
AT romerosandraraquel molecularidentificationofsarcocystisaucheniaeinthewildsouthamericancamelidvicugnavicugna
AT schnittgerleonhard molecularidentificationofsarcocystisaucheniaeinthewildsouthamericancamelidvicugnavicugna
AT florinchristensenmonica molecularidentificationofsarcocystisaucheniaeinthewildsouthamericancamelidvicugnavicugna