Analysis of management factors influencing Anaplasma marginale transmission
The aim of this study was to identify factors that play a key role in the epidemiology of bovine anaplasmosis by adapting a model primarily developed for cattle babesiosis. A cross-sectional observational study was conducted to study the proportion of calf herds in endemic stability/instability for...
| Autores principales: | , , , , , |
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| Formato: | Artículo |
| Lenguaje: | Inglés |
| Publicado: |
Elsevier
2024
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| Acceso en línea: | http://hdl.handle.net/20.500.12123/18915 https://www.sciencedirect.com/science/article/abs/pii/S0304401724001729 https://doi.org/10.1016/j.vetpar.2024.110283 |
| _version_ | 1855486266892615680 |
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| author | Morel, Nicolas Mastropaolo, Mariano Torioni, Susana Marta Signorini Porchiett, Marcelo Lisandro Mangold, Atilio Jose Primo, María Evangelina |
| author_browse | Mangold, Atilio Jose Mastropaolo, Mariano Morel, Nicolas Primo, María Evangelina Signorini Porchiett, Marcelo Lisandro Torioni, Susana Marta |
| author_facet | Morel, Nicolas Mastropaolo, Mariano Torioni, Susana Marta Signorini Porchiett, Marcelo Lisandro Mangold, Atilio Jose Primo, María Evangelina |
| author_sort | Morel, Nicolas |
| collection | INTA Digital |
| description | The aim of this study was to identify factors that play a key role in the epidemiology of bovine anaplasmosis by adapting a model primarily developed for cattle babesiosis. A cross-sectional observational study was conducted to study the proportion of calf herds in endemic stability/instability for A. marginale in a semi-arid area of Argentina. The A. marginale inoculation rate (h) was calculated from age-specific seroprevalence using double-antigen sandwich ELISA in 58 herds of 4.5–8.5-month–old calves. Herds were considered to be in endemic instability (EI) at h < 0.005 and, therefore, at risk of anaplasmosis outbreaks. A generalized linear model was performed to explore husbandry practices associated with differences in A. marginale transmission. Additionally, spatial clustering of herds with the same immunological status was analyzed using spatial scan statistics (SatScan, Bernoulli model). Spearman's correlation was used to explore a possible association between A. marginale h and Babesia bovis and B. bigemina h (data obtained in previous works). Almost half (43 %) of the herds were in the EI zone for A. marginale. Calves raised under forage combinations had a greater risk of being in EI (OR = 5.41, CI95 %OR = 1.43–20.41) than those reared exclusively on permanent pastures, where cattle density is higher (P = 0.01). Moreover, calves from herds treated only with pyrethroids to control ticks had more chances of being in EI (OR = 4.16, CI95 %OR = 1.12–15.38) than calves from herds receiving different acaricide combinations (P = 0.03). Calves from herds subjected to more than two treatments against Haematobia irritans had higher odds for EI (OR = 5.69, CI95 %OR = 1.24–26.11) than those from herds using fewer than two treatments (P = 0.02). The spatial analysis revealed no spatial clustering of the immune status of the herds (P = 0.67 and P = 0.74 for low and high incidence rates, respectively). A significant variation between farms was observed in A. marginale h (CV = 90.38 %). The correlation analysis revealed a strong epidemiological link of A. marginale h with B. bovis h (Rho=0.794, P<0.001) and B. bigemina h (Rho=0.839, P<0.001). Given that R. microplus is the only vector of B. bovis and B. bigemina in the region, the results of this work strongly suggest an active and significant role of R. microplus in the transmission of A. marginale. |
| format | Artículo |
| id | INTA18915 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | INTA189152024-08-14T11:15:17Z Analysis of management factors influencing Anaplasma marginale transmission Morel, Nicolas Mastropaolo, Mariano Torioni, Susana Marta Signorini Porchiett, Marcelo Lisandro Mangold, Atilio Jose Primo, María Evangelina Anaplasmosis Ganado Bovino Densidad Cattle Density Anaplasma marginale Rhipicephalus microplus The aim of this study was to identify factors that play a key role in the epidemiology of bovine anaplasmosis by adapting a model primarily developed for cattle babesiosis. A cross-sectional observational study was conducted to study the proportion of calf herds in endemic stability/instability for A. marginale in a semi-arid area of Argentina. The A. marginale inoculation rate (h) was calculated from age-specific seroprevalence using double-antigen sandwich ELISA in 58 herds of 4.5–8.5-month–old calves. Herds were considered to be in endemic instability (EI) at h < 0.005 and, therefore, at risk of anaplasmosis outbreaks. A generalized linear model was performed to explore husbandry practices associated with differences in A. marginale transmission. Additionally, spatial clustering of herds with the same immunological status was analyzed using spatial scan statistics (SatScan, Bernoulli model). Spearman's correlation was used to explore a possible association between A. marginale h and Babesia bovis and B. bigemina h (data obtained in previous works). Almost half (43 %) of the herds were in the EI zone for A. marginale. Calves raised under forage combinations had a greater risk of being in EI (OR = 5.41, CI95 %OR = 1.43–20.41) than those reared exclusively on permanent pastures, where cattle density is higher (P = 0.01). Moreover, calves from herds treated only with pyrethroids to control ticks had more chances of being in EI (OR = 4.16, CI95 %OR = 1.12–15.38) than calves from herds receiving different acaricide combinations (P = 0.03). Calves from herds subjected to more than two treatments against Haematobia irritans had higher odds for EI (OR = 5.69, CI95 %OR = 1.24–26.11) than those from herds using fewer than two treatments (P = 0.02). The spatial analysis revealed no spatial clustering of the immune status of the herds (P = 0.67 and P = 0.74 for low and high incidence rates, respectively). A significant variation between farms was observed in A. marginale h (CV = 90.38 %). The correlation analysis revealed a strong epidemiological link of A. marginale h with B. bovis h (Rho=0.794, P<0.001) and B. bigemina h (Rho=0.839, P<0.001). Given that R. microplus is the only vector of B. bovis and B. bigemina in the region, the results of this work strongly suggest an active and significant role of R. microplus in the transmission of A. marginale. Instituto Nacional de Tecnología Agropecuaria (INTA) DEC 9392. Asociación Cooperadora de INTA Rafaela. EEA Rafaela Fil: Morel, Nicolas. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela. Instituto de Investigación de la Cadena Láctea (IdICaL); Argentina Fil: Morel, Nicolas. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación de la Cadena Láctea (IdICaL); Argentina Fil: Mastropaolo, Mariano. Zoologische Staatssammlung München; Alemania Fil: Torioni, Susana. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela. Instituto de Investigación de la Cadena Láctea (IdICaL); Argentina Fil: Torioni, Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación de la Cadena Láctea (IdICaL); Argentina Fil: Signorini, Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación de la Cadena Láctea (IdICaL); Argentina Fil: Signorini, Marcelo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela. Instituto de Investigación de la Cadena Láctea (IdICaL); Argentina Fil: Mangold, Atilio José. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela. Instituto de Investigación de la Cadena Láctea (IdICaL); Argentina Fil: Mangold, Atilio José. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación de la Cadena Láctea (IdICaL); Argentina Fil: Primo, María Evangelina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación de la Cadena Láctea (IdICaL); Argentina Fil: Primo, María Evangelina. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela. Instituto de Investigación de la Cadena Láctea (IdICaL); Argentina 2024-08-14T11:00:28Z 2024-08-14T11:00:28Z 2024-10 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/18915 https://www.sciencedirect.com/science/article/abs/pii/S0304401724001729 0304-4017 1873-2550 https://doi.org/10.1016/j.vetpar.2024.110283 eng info:eu-repo/semantics/restrictedAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Elsevier Veterinary Parasitology 331 : 110283 (October 2024) |
| spellingShingle | Anaplasmosis Ganado Bovino Densidad Cattle Density Anaplasma marginale Rhipicephalus microplus Morel, Nicolas Mastropaolo, Mariano Torioni, Susana Marta Signorini Porchiett, Marcelo Lisandro Mangold, Atilio Jose Primo, María Evangelina Analysis of management factors influencing Anaplasma marginale transmission |
| title | Analysis of management factors influencing Anaplasma marginale transmission |
| title_full | Analysis of management factors influencing Anaplasma marginale transmission |
| title_fullStr | Analysis of management factors influencing Anaplasma marginale transmission |
| title_full_unstemmed | Analysis of management factors influencing Anaplasma marginale transmission |
| title_short | Analysis of management factors influencing Anaplasma marginale transmission |
| title_sort | analysis of management factors influencing anaplasma marginale transmission |
| topic | Anaplasmosis Ganado Bovino Densidad Cattle Density Anaplasma marginale Rhipicephalus microplus |
| url | http://hdl.handle.net/20.500.12123/18915 https://www.sciencedirect.com/science/article/abs/pii/S0304401724001729 https://doi.org/10.1016/j.vetpar.2024.110283 |
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