Negative modulation of SA signaling components by the capsid protein of tobacco mosaic virus is required for viral long-distance movement

An important aspect of plant–virus interaction is the way viruses dynamically move over long distances and how plant immunity modulates viral systemic movement. Salicylic acid (SA), a well-characterized hormone responsible for immune responses against virus, is activated through different transcript...

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Detalles Bibliográficos
Autores principales: Venturuzzi, Andrea Laura, Rodriguez, Maria Cecilia, Conti, Gabriela, Leone, Melisa, Caro, Maria Del Pilar, Montecchia, Juan Francisco, Zavallo, Diego, Asurmendi, Sebastian
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: Wiley 2024
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/18792
https://onlinelibrary.wiley.com/doi/10.1111/tpj.15268
https://doi.org/10.1111/tpj.15268
Descripción
Sumario:An important aspect of plant–virus interaction is the way viruses dynamically move over long distances and how plant immunity modulates viral systemic movement. Salicylic acid (SA), a well-characterized hormone responsible for immune responses against virus, is activated through different transcription factors including TGA and WRKY. In tobamoviruses, evidence suggests that capsid protein (CP) is required for long-distance movement, although its precise role has not been fully characterized yet. Previously, we showed that the CP of Tobacco Mosaic Virus (TMV)-Cg negatively modulates the SA-mediated defense. In this study, we analyzed the impact of SA-defense mechanism on the long-distance transport of a truncated version of TMV (TMV ∆CP virus) that cannot move to systemic tissues. The study showed that the negative modulation of NPR1 and TGA10 factors allows the long-distance transport of TMV ∆CP virus. Moreover, we observed that the stabilization of DELLA proteins promotes TMV ∆CP systemic movement. We also characterized a group of genes, part of a network modulated by CP, involved in TMV ∆CP long-distance transport. Altogether, our results indicate that CP-mediated downregulation of SA signaling pathway is required for the virus systemic movement, and this role of CP may be linked to its ability to stabilize DELLA proteins.