Epidemiological characterization of isolates of Salmonella enterica and shiga toxin-producing Escherichia coli from backyard production system animals in the Valparaíso and metropolitana regions

Backyard production systems (BPS) are distributed worldwide, rearing animals recognized as reservoirs of Salmonella enterica and Shiga toxin-producing Escherichia coli (STEC), both zoonotic pathogens. The aim of this study was to characterize isolates of both pathogens obtained from animals raised i...

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Autores principales: Urzúa-Encina, Constanza, Fernández-Sanhueza, Bastián, Pavez-Muñoz, Erika, Ramírez-Toloza, Galia, Tomazic, Mariela Luján, Rodriguez, Anabel Elisa, Alegría-Morán, Raúl
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: MDPI 2024
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/18505
https://www.mdpi.com/2076-2615/13/15/2444
https://doi.org/10.3390/ani13152444
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author Urzúa-Encina, Constanza
Fernández-Sanhueza, Bastián
Pavez-Muñoz, Erika
Ramírez-Toloza, Galia
Tomazic, Mariela Luján
Rodriguez, Anabel Elisa
Alegría-Morán, Raúl
author_browse Alegría-Morán, Raúl
Fernández-Sanhueza, Bastián
Pavez-Muñoz, Erika
Ramírez-Toloza, Galia
Rodriguez, Anabel Elisa
Tomazic, Mariela Luján
Urzúa-Encina, Constanza
author_facet Urzúa-Encina, Constanza
Fernández-Sanhueza, Bastián
Pavez-Muñoz, Erika
Ramírez-Toloza, Galia
Tomazic, Mariela Luján
Rodriguez, Anabel Elisa
Alegría-Morán, Raúl
author_sort Urzúa-Encina, Constanza
collection INTA Digital
description Backyard production systems (BPS) are distributed worldwide, rearing animals recognized as reservoirs of Salmonella enterica and Shiga toxin-producing Escherichia coli (STEC), both zoonotic pathogens. The aim of this study was to characterize isolates of both pathogens obtained from animals raised in BPS from two central Chile regions. The presence of pathogens was determined by bacterial culture and confirmatory PCR for each sampled BPS, calculating positivity rates. Multivariate logistic regression was used to determine risk factors. Additionally, phenotypic antimicrobial resistance was determined. A positivity rate of 2.88% for S. enterica and 14.39% for STEC was determined for the complete study region (Valparaíso and Metropolitana regions). Risk factor analysis suggests that the presence of ruminants (OR = 1.03; 95% CI = 1.002–1.075) increases the risk of STEC-positive BPS, and the presence of ruminants (OR = 1.05; 95% CI = 1.002–1.075) and the animal handlers being exclusively women (OR = 3.54; 95% CI = 1.029–12.193) increase the risk for S. enterica/STEC positivity. Eighty percent of S. enterica isolates were multidrug resistant, and all STEC were resistant to Cephalexin. This study evidences the circulation of multidrug-resistant zoonotic bacterial strains in animals kept in BPS and the presence of factors that modify the risk of BPS positivity for both pathogens.
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spelling INTA185052024-07-15T12:20:24Z Epidemiological characterization of isolates of Salmonella enterica and shiga toxin-producing Escherichia coli from backyard production system animals in the Valparaíso and metropolitana regions Urzúa-Encina, Constanza Fernández-Sanhueza, Bastián Pavez-Muñoz, Erika Ramírez-Toloza, Galia Tomazic, Mariela Luján Rodriguez, Anabel Elisa Alegría-Morán, Raúl Risk Factors Antimicrobial Resistance One Health Approach Isolation Factores de Riesgo Resistencia a los Antimicrobianos Enfoque Una Salud Escherichia coli Aislamiento Salmonella enterica Valparaíso, Chile Productor de Toxina Shiga Shiga toxin-producing Backyard production systems (BPS) are distributed worldwide, rearing animals recognized as reservoirs of Salmonella enterica and Shiga toxin-producing Escherichia coli (STEC), both zoonotic pathogens. The aim of this study was to characterize isolates of both pathogens obtained from animals raised in BPS from two central Chile regions. The presence of pathogens was determined by bacterial culture and confirmatory PCR for each sampled BPS, calculating positivity rates. Multivariate logistic regression was used to determine risk factors. Additionally, phenotypic antimicrobial resistance was determined. A positivity rate of 2.88% for S. enterica and 14.39% for STEC was determined for the complete study region (Valparaíso and Metropolitana regions). Risk factor analysis suggests that the presence of ruminants (OR = 1.03; 95% CI = 1.002–1.075) increases the risk of STEC-positive BPS, and the presence of ruminants (OR = 1.05; 95% CI = 1.002–1.075) and the animal handlers being exclusively women (OR = 3.54; 95% CI = 1.029–12.193) increase the risk for S. enterica/STEC positivity. Eighty percent of S. enterica isolates were multidrug resistant, and all STEC were resistant to Cephalexin. This study evidences the circulation of multidrug-resistant zoonotic bacterial strains in animals kept in BPS and the presence of factors that modify the risk of BPS positivity for both pathogens. Instituto de Patobiología Fil: Urzúa-Encina, Constanza. Universidad de Chile. Facultad de Ciencias Veterinarias y Pecuarias. Departamento de Medicina Preventiva Animal; Chile Fil: Urzúa-Encina, Constanza. Universidad de Chile. Facultad de Ciencias Veterinarias y Pecuarias. Laboratorio Centralizado de Investigación Veterinaria; Chile Fil: Fernández-Sanhueza, Bastián. Universidad de Chile. Facultad de Ciencias Veterinarias y Pecuarias. Departamento de Medicina Preventiva Animal; Chile Fil: Fernández-Sanhueza, Bastián. Universidad de Chile. Facultad de Ciencias Veterinarias y Pecuarias. Laboratorio Centralizado de Investigación Veterinaria; Chile Fil: Fernández-Sanhueza, Bastián. Universidad Santo Tomás. Facultad de Recursos Naturales y Medicina Veterinaria. Escuela de Medicina Veterinaria, Sede Santiago; Chile Fil: Pavez-Muñoz, Erika. Universidad de Chile. Facultad de Ciencias Veterinarias y Pecuarias. Departamento de Medicina Preventiva Animal; Chile Fil: Pavez-Muñoz, Erika. Universidad de Chile. Facultad de Ciencias Veterinarias y Pecuarias. Laboratorio Centralizado de Investigación Veterinaria; Chile Fil: Ramírez-Toloza, Galia. Universidad de Chile. Facultad de Ciencias Veterinarias y Pecuarias. Departamento de Medicina Preventiva Animal; Chile Fil: Ramírez-Toloza, Galia. Universidad de Chile. Facultad de Ciencias Veterinarias y Pecuarias. Laboratorio Centralizado de Investigación Veterinaria; Chile Fil: Tomazic, Mariela Luján. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología Veterinaria; Argentina Fil: Tomazic, Mariela Luján. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Tomazic, Mariela Luján. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina Fil: Rodriguez, Anabel Elisa. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología Veterinaria; Argentina Fil: Rodriguez, Anabel Elisa. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Alegría-Morán, Raúl. Universidad Santo Tomás. Facultad de Recursos Naturales y Medicina Veterinaria. Escuela de Medicina Veterinaria, Sede Santiago; Chile 2024-07-15T11:20:25Z 2024-07-15T11:20:25Z 2023-08 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/18505 https://www.mdpi.com/2076-2615/13/15/2444 2076-2615 https://doi.org/10.3390/ani13152444 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf MDPI Animals 13 (15) : 2444 (Agosto 2023)
spellingShingle Risk Factors
Antimicrobial Resistance
One Health Approach
Isolation
Factores de Riesgo
Resistencia a los Antimicrobianos
Enfoque Una Salud
Escherichia coli
Aislamiento
Salmonella enterica
Valparaíso, Chile
Productor de Toxina Shiga
Shiga toxin-producing
Urzúa-Encina, Constanza
Fernández-Sanhueza, Bastián
Pavez-Muñoz, Erika
Ramírez-Toloza, Galia
Tomazic, Mariela Luján
Rodriguez, Anabel Elisa
Alegría-Morán, Raúl
Epidemiological characterization of isolates of Salmonella enterica and shiga toxin-producing Escherichia coli from backyard production system animals in the Valparaíso and metropolitana regions
title Epidemiological characterization of isolates of Salmonella enterica and shiga toxin-producing Escherichia coli from backyard production system animals in the Valparaíso and metropolitana regions
title_full Epidemiological characterization of isolates of Salmonella enterica and shiga toxin-producing Escherichia coli from backyard production system animals in the Valparaíso and metropolitana regions
title_fullStr Epidemiological characterization of isolates of Salmonella enterica and shiga toxin-producing Escherichia coli from backyard production system animals in the Valparaíso and metropolitana regions
title_full_unstemmed Epidemiological characterization of isolates of Salmonella enterica and shiga toxin-producing Escherichia coli from backyard production system animals in the Valparaíso and metropolitana regions
title_short Epidemiological characterization of isolates of Salmonella enterica and shiga toxin-producing Escherichia coli from backyard production system animals in the Valparaíso and metropolitana regions
title_sort epidemiological characterization of isolates of salmonella enterica and shiga toxin producing escherichia coli from backyard production system animals in the valparaiso and metropolitana regions
topic Risk Factors
Antimicrobial Resistance
One Health Approach
Isolation
Factores de Riesgo
Resistencia a los Antimicrobianos
Enfoque Una Salud
Escherichia coli
Aislamiento
Salmonella enterica
Valparaíso, Chile
Productor de Toxina Shiga
Shiga toxin-producing
url http://hdl.handle.net/20.500.12123/18505
https://www.mdpi.com/2076-2615/13/15/2444
https://doi.org/10.3390/ani13152444
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