Corrugated intimal surface of the ovine aorta: when physiology resembles pathology
The aortic lumen in healthy animals is characterized by a smooth, whitish surface, but sheep have macroscopic corrugation of the intimal surface in the thoracic aorta (TA). Our aim was to determine if this finding was pathological or physiological. Thirteen sheep aortas were included in this work to...
| Main Authors: | , , , , , , , |
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| Format: | Artículo |
| Language: | Inglés |
| Published: |
Elsevier
2024
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.12123/18200 https://www.sciencedirect.com/science/article/pii/S0021997524002366 https://doi.org/10.1016/j.jcpa.2024.03.207 |
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| author | Calvo-Sánchez, Natalia Rodríguez-Largo, Ana Puzol, Leonor Miguel, Ricardo de Pérez, Estela Gómez, Álex Micheloud, Juan Francisco Lujan, Lluís |
| author_browse | Calvo-Sánchez, Natalia Gómez, Álex Lujan, Lluís Micheloud, Juan Francisco Miguel, Ricardo de Puzol, Leonor Pérez, Estela Rodríguez-Largo, Ana |
| author_facet | Calvo-Sánchez, Natalia Rodríguez-Largo, Ana Puzol, Leonor Miguel, Ricardo de Pérez, Estela Gómez, Álex Micheloud, Juan Francisco Lujan, Lluís |
| author_sort | Calvo-Sánchez, Natalia |
| collection | INTA Digital |
| description | The aortic lumen in healthy animals is characterized by a smooth, whitish surface, but sheep have macroscopic corrugation of the intimal surface in the thoracic aorta (TA). Our aim was to determine if this finding was pathological or physiological. Thirteen sheep aortas were included in this work together with aortas from cattle (n = 3), a goat (n = 1), horses (n = 4), dogs (n = 2), rabbits (n = 2) and a pig (n = 1). A corrugated intimal surface in the TA was seen in all the sheep and the goat but was less evident in the cattle. Histologically, in sheep the TA intimal surface was seen to have multifocal bulging areas that protruded into the lumen. The outer half of the tunica media had numerous, randomly distributed muscle islands that disrupted the arrangement of the elastic lamella, displacing them towards the lumen. We conclude that the intimal corrugation of the TA in sheep is physiological and must not be misinterpreted as pathological. |
| format | Artículo |
| id | INTA18200 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | INTA182002024-06-18T13:47:19Z Corrugated intimal surface of the ovine aorta: when physiology resembles pathology Calvo-Sánchez, Natalia Rodríguez-Largo, Ana Puzol, Leonor Miguel, Ricardo de Pérez, Estela Gómez, Álex Micheloud, Juan Francisco Lujan, Lluís Ovinos Fisiología Animal Enfermedades Vasculares Sheep Aorta Animal Physiology Vascular Diseases The aortic lumen in healthy animals is characterized by a smooth, whitish surface, but sheep have macroscopic corrugation of the intimal surface in the thoracic aorta (TA). Our aim was to determine if this finding was pathological or physiological. Thirteen sheep aortas were included in this work together with aortas from cattle (n = 3), a goat (n = 1), horses (n = 4), dogs (n = 2), rabbits (n = 2) and a pig (n = 1). A corrugated intimal surface in the TA was seen in all the sheep and the goat but was less evident in the cattle. Histologically, in sheep the TA intimal surface was seen to have multifocal bulging areas that protruded into the lumen. The outer half of the tunica media had numerous, randomly distributed muscle islands that disrupted the arrangement of the elastic lamella, displacing them towards the lumen. We conclude that the intimal corrugation of the TA in sheep is physiological and must not be misinterpreted as pathological. EEA Salta Fil: Calvo-Sánchez, Natalia. Universidad de Zaragoza. Veterinary Faculty. Department of Animal Pathology; España Fil: Calvo-Sánchez, Natalia. Universidad de Zaragoza. Veterinary Faculty. AgriFood Institute of Aragon; España Fil: Rodríguez-Largo, Ana. Universidad de Zaragoza. Veterinary Faculty. Department of Animal Pathology; España Fil: Puzol, Leonor. Universidad de Zaragoza. Veterinary Faculty. Department of Animal Pathology; España Fil: Miguel, Ricardo de. Universidad de Zaragoza. Veterinary Faculty. Department of Animal Pathology; España Fil: Pérez, Estela. Universidad de Zaragoza. Veterinary Faculty. Department of Animal Pathology; España Fil: Pérez, Estela. Universidad de Zaragoza. Veterinary Faculty. AgriFood Institute of Aragon; España Fil: Gómez, Álex. Universidad de Zaragoza. Veterinary Faculty. Department of Animal Pathology; España Fil: Gómez, Álex. Universidad de Zaragoza. Veterinary Faculty. AgriFood Institute of Aragon; España Fil: Micheloud, Juan Francisco. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Salta; Argentina. Fil: Micheloud, Juan Francisco. Universidad Católica de Salta, Argentina. Fil: Micheloud, Juan Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Lujan, Lluís. Universidad de Zaragoza. Veterinary Faculty. Department of Animal Pathology; España Fil: Lujan, Lluís. Universidad de Zaragoza. Veterinary Faculty. AgriFood Institute of Aragon; España 2024-06-18T13:44:29Z 2024-06-18T13:44:29Z 2024-05 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/18200 https://www.sciencedirect.com/science/article/pii/S0021997524002366 0021-9975 1532-3129 https://doi.org/10.1016/j.jcpa.2024.03.207 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Elsevier Journal of Comparative Pathology 211 : 8-11. (May 2024) |
| spellingShingle | Ovinos Fisiología Animal Enfermedades Vasculares Sheep Aorta Animal Physiology Vascular Diseases Calvo-Sánchez, Natalia Rodríguez-Largo, Ana Puzol, Leonor Miguel, Ricardo de Pérez, Estela Gómez, Álex Micheloud, Juan Francisco Lujan, Lluís Corrugated intimal surface of the ovine aorta: when physiology resembles pathology |
| title | Corrugated intimal surface of the ovine aorta: when physiology resembles pathology |
| title_full | Corrugated intimal surface of the ovine aorta: when physiology resembles pathology |
| title_fullStr | Corrugated intimal surface of the ovine aorta: when physiology resembles pathology |
| title_full_unstemmed | Corrugated intimal surface of the ovine aorta: when physiology resembles pathology |
| title_short | Corrugated intimal surface of the ovine aorta: when physiology resembles pathology |
| title_sort | corrugated intimal surface of the ovine aorta when physiology resembles pathology |
| topic | Ovinos Fisiología Animal Enfermedades Vasculares Sheep Aorta Animal Physiology Vascular Diseases |
| url | http://hdl.handle.net/20.500.12123/18200 https://www.sciencedirect.com/science/article/pii/S0021997524002366 https://doi.org/10.1016/j.jcpa.2024.03.207 |
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