Oro-ruminal sampling device and technique for rapid collection of rumen content and improved recovery of solid fractions for microbiome analysis

Rumen fistulation is a widely used procedure that allows for collection of ruminal contents. However, fistulation is an invasive and costly procedure that generally limits the number of animals that can be recruited for experiments, thus encouraging the use of alternative techniques such as the intr...

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Main Authors: Miccoli, Florencia Estefanía, Galarza, Roxana Ivon, Juliano, Nicolás, Ferreyra, S., Maresca, Sebastian, Lopez Valiente, Sebastian, Guerrero, Leandro Demian, Palladino, Rafael Alejandro, Albornoz, Rodrigo I.
Format: info:ar-repo/semantics/artículo
Language:Inglés
Published: Elsevier 2024
Subjects:
Online Access:http://hdl.handle.net/20.500.12123/18093
https://www.sciencedirect.com/science/article/pii/S2666910224000930
https://doi.org/10.3168/jdsc.2023-0536
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author Miccoli, Florencia Estefanía
Galarza, Roxana Ivon
Juliano, Nicolás
Ferreyra, S.
Maresca, Sebastian
Lopez Valiente, Sebastian
Guerrero, Leandro Demian
Palladino, Rafael Alejandro
Albornoz, Rodrigo I.
author_browse Albornoz, Rodrigo I.
Ferreyra, S.
Galarza, Roxana Ivon
Guerrero, Leandro Demian
Juliano, Nicolás
Lopez Valiente, Sebastian
Maresca, Sebastian
Miccoli, Florencia Estefanía
Palladino, Rafael Alejandro
author_facet Miccoli, Florencia Estefanía
Galarza, Roxana Ivon
Juliano, Nicolás
Ferreyra, S.
Maresca, Sebastian
Lopez Valiente, Sebastian
Guerrero, Leandro Demian
Palladino, Rafael Alejandro
Albornoz, Rodrigo I.
author_sort Miccoli, Florencia Estefanía
collection INTA Digital
description Rumen fistulation is a widely used procedure that allows for collection of ruminal contents. However, fistulation is an invasive and costly procedure that generally limits the number of animals that can be recruited for experiments, thus encouraging the use of alternative techniques such as the intra-esophageal tube technique. One of the challenges of this technique is the limited ability to collect solid fractions from the rumen content pool which may impact the microbial community structure in the sample, particularly affecting the recovery and characterization of solid adherent-bacteria. We developed an intra-esophageal tube rumen sampling technique and device referred to as ‘Rumen Sampler MG’ with the aim of increasing the recovery of solid fractions from rumen content compared with other oro-ruminal sampling methods. The ‘Rumen Sampler MG’ device consists of a manual pump fitted with a barometer and an intra-esophageal flexible PVC tube with beveled terminal edge allowing for minimal clogging of the sampling tubing and a rapid flux of contents being sampled. Nine lactating Holstein-Friesian dairy cows (554.6 ± 25.2 kg BW; 8.3 ± 3.3 DIM) were recruited to evaluate the proposed method. During the procedure, animals were safely restrained in a chute and administered with a low dosage of a neuroleptic drug to reduce animal stress during sampling. An endoscopic camera was inserted into the reticulo-rumen through the esophagus to identify the sampling location and determine the length of the sampling tube necessary to reach the desired location. Following, the intra-esophageal sampling tube connected to a manual pump was inserted for collection of rumen contents. Samples collected did not present visual evidence of saliva contamination (e.g., high viscosity) and their pH ranged within expected values (6.33 - 7.04) for samples collected from the reticulo-rumen. Each sample contained 35–40% wet solids volume. Individual dry matter intake and milk production of cows continued to increase after sampling as expected for cows in the early postpartum period, suggesting that the sampling procedure did not affect cow performance. Results from microbiome analysis of rumen content samples suggest that the relative abundances of the main bacterial phyla are consistent with those from samples collected from dairy cows via rumen fistula in previous studies. The device and technique proposed allow for adequate samples of ruminal liquid and solid contents to be collected for microbiome analysis without disruption of animal performance.
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institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
language Inglés
publishDate 2024
publishDateRange 2024
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publisherStr Elsevier
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spelling INTA180932024-06-10T11:57:39Z Oro-ruminal sampling device and technique for rapid collection of rumen content and improved recovery of solid fractions for microbiome analysis Miccoli, Florencia Estefanía Galarza, Roxana Ivon Juliano, Nicolás Ferreyra, S. Maresca, Sebastian Lopez Valiente, Sebastian Guerrero, Leandro Demian Palladino, Rafael Alejandro Albornoz, Rodrigo I. Rumen Sampling Cattle Microbiomes Muestreo Ganado Bovino Microbiomas Rumen fistulation is a widely used procedure that allows for collection of ruminal contents. However, fistulation is an invasive and costly procedure that generally limits the number of animals that can be recruited for experiments, thus encouraging the use of alternative techniques such as the intra-esophageal tube technique. One of the challenges of this technique is the limited ability to collect solid fractions from the rumen content pool which may impact the microbial community structure in the sample, particularly affecting the recovery and characterization of solid adherent-bacteria. We developed an intra-esophageal tube rumen sampling technique and device referred to as ‘Rumen Sampler MG’ with the aim of increasing the recovery of solid fractions from rumen content compared with other oro-ruminal sampling methods. The ‘Rumen Sampler MG’ device consists of a manual pump fitted with a barometer and an intra-esophageal flexible PVC tube with beveled terminal edge allowing for minimal clogging of the sampling tubing and a rapid flux of contents being sampled. Nine lactating Holstein-Friesian dairy cows (554.6 ± 25.2 kg BW; 8.3 ± 3.3 DIM) were recruited to evaluate the proposed method. During the procedure, animals were safely restrained in a chute and administered with a low dosage of a neuroleptic drug to reduce animal stress during sampling. An endoscopic camera was inserted into the reticulo-rumen through the esophagus to identify the sampling location and determine the length of the sampling tube necessary to reach the desired location. Following, the intra-esophageal sampling tube connected to a manual pump was inserted for collection of rumen contents. Samples collected did not present visual evidence of saliva contamination (e.g., high viscosity) and their pH ranged within expected values (6.33 - 7.04) for samples collected from the reticulo-rumen. Each sample contained 35–40% wet solids volume. Individual dry matter intake and milk production of cows continued to increase after sampling as expected for cows in the early postpartum period, suggesting that the sampling procedure did not affect cow performance. Results from microbiome analysis of rumen content samples suggest that the relative abundances of the main bacterial phyla are consistent with those from samples collected from dairy cows via rumen fistula in previous studies. The device and technique proposed allow for adequate samples of ruminal liquid and solid contents to be collected for microbiome analysis without disruption of animal performance. EEA Cuenca del Salado Fil: Miccoli, Florencia. Universidad Nacional de Lomas de Zamora. Facultad de Ciencias Agrarias; Argentina Fil: Miccoli, Florencia. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal; Argentina Fil: Galarza, Roxana Ivon. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Cuenca del Salado. Agencia de Extensión Rural Chascomús; Argentina Fil: Juliano, N. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal; Argentina Fil: Juliano, N. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular “Dr. Héctor N. Torres”; Argentina Fil: Ferreyra, S. Universidad Nacional de Lomas de Zamora. Facultad de Ciencias Agrarias; Argentina Fil: Maresca, Sebastian. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Cuenca del Salado; Argentina Fil: Lopez Valiente, Sebastian. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Cuenca del Salado; Argentina Fil: Guerrero, Leandro Demian. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular “Dr. Héctor N. Torres”; Argentina Fil: Palladino, Rafael Alejandro. Universidad Nacional de Lomas de Zamora. Facultad de Ciencias Agrarias; Argentina Fil: Palladino, Rafael Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular “Dr. Héctor N. Torres”; Argentina Fil: Albornoz, Rodrigo I. Dairy Australia; Australia 2024-06-10T11:52:00Z 2024-06-10T11:52:00Z 2024-05 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion http://hdl.handle.net/20.500.12123/18093 https://www.sciencedirect.com/science/article/pii/S2666910224000930 2666-9102 https://doi.org/10.3168/jdsc.2023-0536 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Elsevier JDS Communications : 1-5 (Available online 31 May 2024)
spellingShingle Rumen
Sampling
Cattle
Microbiomes
Muestreo
Ganado Bovino
Microbiomas
Miccoli, Florencia Estefanía
Galarza, Roxana Ivon
Juliano, Nicolás
Ferreyra, S.
Maresca, Sebastian
Lopez Valiente, Sebastian
Guerrero, Leandro Demian
Palladino, Rafael Alejandro
Albornoz, Rodrigo I.
Oro-ruminal sampling device and technique for rapid collection of rumen content and improved recovery of solid fractions for microbiome analysis
title Oro-ruminal sampling device and technique for rapid collection of rumen content and improved recovery of solid fractions for microbiome analysis
title_full Oro-ruminal sampling device and technique for rapid collection of rumen content and improved recovery of solid fractions for microbiome analysis
title_fullStr Oro-ruminal sampling device and technique for rapid collection of rumen content and improved recovery of solid fractions for microbiome analysis
title_full_unstemmed Oro-ruminal sampling device and technique for rapid collection of rumen content and improved recovery of solid fractions for microbiome analysis
title_short Oro-ruminal sampling device and technique for rapid collection of rumen content and improved recovery of solid fractions for microbiome analysis
title_sort oro ruminal sampling device and technique for rapid collection of rumen content and improved recovery of solid fractions for microbiome analysis
topic Rumen
Sampling
Cattle
Microbiomes
Muestreo
Ganado Bovino
Microbiomas
url http://hdl.handle.net/20.500.12123/18093
https://www.sciencedirect.com/science/article/pii/S2666910224000930
https://doi.org/10.3168/jdsc.2023-0536
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