Whole Genome Sequence-Based Analysis of Bovine Gammaherpesvirus 4 Isolated from Bovine Abortions
Bovine gammaherpesvirus 4 (BoGHV4) is a member of the Gammaherspivirinae subfamily, Rhadinovirus genus. Its natural host is the bovine, and it is prevalent among the global cattle population. Although the complete genome of BoGHV4 has been successfully sequenced, the functions of most of its genes r...
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| Format: | Artículo |
| Language: | Inglés |
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Multidisciplinary Digital Publishing Institute, MDPI
2024
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| Online Access: | http://hdl.handle.net/20.500.12123/18023 https://www.mdpi.com/1999-4915/16/5/739 https://doi.org/10.3390/v16050739 |
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| author | Romeo, Florencia Spetter, Maximiliano Joaquín Pereyra, Susana Beatriz Morán, Pedro Edgardo González Altamiranda, Erika Louge Uriarte, Enrique Leopoldo Odeon, Anselmo Carlos Pérez, Sandra Elizabeth Verna, Andrea Elizabeth |
| author_browse | González Altamiranda, Erika Louge Uriarte, Enrique Leopoldo Morán, Pedro Edgardo Odeon, Anselmo Carlos Pereyra, Susana Beatriz Pérez, Sandra Elizabeth Romeo, Florencia Spetter, Maximiliano Joaquín Verna, Andrea Elizabeth |
| author_facet | Romeo, Florencia Spetter, Maximiliano Joaquín Pereyra, Susana Beatriz Morán, Pedro Edgardo González Altamiranda, Erika Louge Uriarte, Enrique Leopoldo Odeon, Anselmo Carlos Pérez, Sandra Elizabeth Verna, Andrea Elizabeth |
| author_sort | Romeo, Florencia |
| collection | INTA Digital |
| description | Bovine gammaherpesvirus 4 (BoGHV4) is a member of the Gammaherspivirinae subfamily, Rhadinovirus genus. Its natural host is the bovine, and it is prevalent among the global cattle population. Although the complete genome of BoGHV4 has been successfully sequenced, the functions of most of its genes remain unknown. Currently, only six strains of BoGHV4, all belonging to Genotype 1, have been sequenced. This is the first report of the nearly complete genome of Argentinean BoGHV4 strains isolated from clinical cases of abortion, representing the first BoGHV4 Genotype 2 and 3 genomes described in the literature. Both Argentinean isolates presented the highest nt p-distance values, indicating a greater level of divergence. Overall, the considerable diversity observed in the complete genomes and open reading frames underscores the distinctiveness of both Argentinean isolates compared to the existing BoGHV4 genomes. These findings support previous studies that categorized the Argentinean BoGHV4 strains 07-435 and 10-154 as Genotypes 3 and 2, respectively. The inclusion of these sequences represents a significant expansion to the currently limited pool of BoGHV4 genomes while providing an important basis to increase the knowledge of local isolates. |
| format | Artículo |
| id | INTA18023 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | Multidisciplinary Digital Publishing Institute, MDPI |
| publisherStr | Multidisciplinary Digital Publishing Institute, MDPI |
| record_format | dspace |
| spelling | INTA180232024-06-04T13:46:29Z Whole Genome Sequence-Based Analysis of Bovine Gammaherpesvirus 4 Isolated from Bovine Abortions Romeo, Florencia Spetter, Maximiliano Joaquín Pereyra, Susana Beatriz Morán, Pedro Edgardo González Altamiranda, Erika Louge Uriarte, Enrique Leopoldo Odeon, Anselmo Carlos Pérez, Sandra Elizabeth Verna, Andrea Elizabeth Bovinae Bovine Herpesvirus Strains Genomes Serology Herpes Virus Bovino Cepas Genomas Serología Argentina Bovine gammaherpesvirus 4 (BoGHV4) is a member of the Gammaherspivirinae subfamily, Rhadinovirus genus. Its natural host is the bovine, and it is prevalent among the global cattle population. Although the complete genome of BoGHV4 has been successfully sequenced, the functions of most of its genes remain unknown. Currently, only six strains of BoGHV4, all belonging to Genotype 1, have been sequenced. This is the first report of the nearly complete genome of Argentinean BoGHV4 strains isolated from clinical cases of abortion, representing the first BoGHV4 Genotype 2 and 3 genomes described in the literature. Both Argentinean isolates presented the highest nt p-distance values, indicating a greater level of divergence. Overall, the considerable diversity observed in the complete genomes and open reading frames underscores the distinctiveness of both Argentinean isolates compared to the existing BoGHV4 genomes. These findings support previous studies that categorized the Argentinean BoGHV4 strains 07-435 and 10-154 as Genotypes 3 and 2, respectively. The inclusion of these sequences represents a significant expansion to the currently limited pool of BoGHV4 genomes while providing an important basis to increase the knowledge of local isolates. EEA Balcarce Fil: Romeo, Florencia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina Fil: Spetter, Maximiliano Joaquín. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina. Comisión de Investigaciones Científicas de la Provincia de Buenos Aires; Argentina. Centro de Investigación Veterinaria de Tandil; Argentina Fil: Pereyra, Susana Beatriz. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina Fil: Morán, Pedro Edgardo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina. Comisión de Investigaciones Científicas de la Provincia de Buenos Aires; Argentina. Centro de Investigación Veterinaria de Tandil; Argentina Fil: González Altamiranda, Erika Analía. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina Fil: Louge Uriarte, Enrique Leopoldo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina Fil: Odeón, Anselmo Carlos. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina Fil: Pérez, Sandra Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina. Comisión de Investigaciones Científicas de la Provincia de Buenos Aires; Argentina. Centro de Investigación Veterinaria de Tandil; Argentina Fil: Verna, Andrea Elizabeth. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina 2024-06-04T13:42:01Z 2024-06-04T13:42:01Z 2024-05-08 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/18023 https://www.mdpi.com/1999-4915/16/5/739 1999-4915 https://doi.org/10.3390/v16050739 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Multidisciplinary Digital Publishing Institute, MDPI Viruses 16 (5) : 739 (May 2024) |
| spellingShingle | Bovinae Bovine Herpesvirus Strains Genomes Serology Herpes Virus Bovino Cepas Genomas Serología Argentina Romeo, Florencia Spetter, Maximiliano Joaquín Pereyra, Susana Beatriz Morán, Pedro Edgardo González Altamiranda, Erika Louge Uriarte, Enrique Leopoldo Odeon, Anselmo Carlos Pérez, Sandra Elizabeth Verna, Andrea Elizabeth Whole Genome Sequence-Based Analysis of Bovine Gammaherpesvirus 4 Isolated from Bovine Abortions |
| title | Whole Genome Sequence-Based Analysis of Bovine Gammaherpesvirus 4 Isolated from Bovine Abortions |
| title_full | Whole Genome Sequence-Based Analysis of Bovine Gammaherpesvirus 4 Isolated from Bovine Abortions |
| title_fullStr | Whole Genome Sequence-Based Analysis of Bovine Gammaherpesvirus 4 Isolated from Bovine Abortions |
| title_full_unstemmed | Whole Genome Sequence-Based Analysis of Bovine Gammaherpesvirus 4 Isolated from Bovine Abortions |
| title_short | Whole Genome Sequence-Based Analysis of Bovine Gammaherpesvirus 4 Isolated from Bovine Abortions |
| title_sort | whole genome sequence based analysis of bovine gammaherpesvirus 4 isolated from bovine abortions |
| topic | Bovinae Bovine Herpesvirus Strains Genomes Serology Herpes Virus Bovino Cepas Genomas Serología Argentina |
| url | http://hdl.handle.net/20.500.12123/18023 https://www.mdpi.com/1999-4915/16/5/739 https://doi.org/10.3390/v16050739 |
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