Genomic evolution of bovine viral diarrhea virus based on complete genome and individual gene analyses

Bovine viral diarrhea virus (BVDV) genome consists of a single-stranded, positive-sense RNA with high genetic diversity. In the last years, significant progress has been achieved in BVDV knowledge evolution through phylodynamic analysis based on the partial 5′UTR sequences, whereas a few studies hav...

Descripción completa

Detalles Bibliográficos
Autores principales: Spetter, Lucas Maximiliano, Louge Uriarte, Enrique Leopoldo, Verna, Andrea Elizabeth, Odeon, Anselmo Carlos, González Altamiranda, Erika
Formato: Artículo
Lenguaje:Inglés
Publicado: Springer 2024
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/17684
https://link.springer.com/article/10.1007/s42770-023-00986-4
https://doi.org/10.1007/s42770-023-00986-4
_version_ 1855486009914949632
author Spetter, Lucas Maximiliano
Louge Uriarte, Enrique Leopoldo
Verna, Andrea Elizabeth
Odeon, Anselmo Carlos
González Altamiranda, Erika
author_browse González Altamiranda, Erika
Louge Uriarte, Enrique Leopoldo
Odeon, Anselmo Carlos
Spetter, Lucas Maximiliano
Verna, Andrea Elizabeth
author_facet Spetter, Lucas Maximiliano
Louge Uriarte, Enrique Leopoldo
Verna, Andrea Elizabeth
Odeon, Anselmo Carlos
González Altamiranda, Erika
author_sort Spetter, Lucas Maximiliano
collection INTA Digital
description Bovine viral diarrhea virus (BVDV) genome consists of a single-stranded, positive-sense RNA with high genetic diversity. In the last years, significant progress has been achieved in BVDV knowledge evolution through phylodynamic analysis based on the partial 5′UTR sequences, whereas a few studies have used other genes or the complete coding sequence (CDS). However, no research has evaluated and compared BVDV evolutionary history based on the complete genome (CG), CDS, and individual genes. In this study, phylodynamic analyses were carried out with BVDV-1 (Pestivirus A) and BVDV-2 (Pestivirus B) CG sequences available on the GenBank database and each genomic region: CDS, UTRs, and individual genes. In comparison to the CG, the estimations for both BVDV species varied according to the dataset used, pointing out the importance of considering the analyzed genomic region when concluding. This study may provide new insight into BVDV evolution history while highlighting the need to increase the available BVDV CG sequences to perform more comprehensive phylodynamic studies in the future.
format Artículo
id INTA17684
institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
language Inglés
publishDate 2024
publishDateRange 2024
publishDateSort 2024
publisher Springer
publisherStr Springer
record_format dspace
spelling INTA176842024-05-09T14:04:35Z Genomic evolution of bovine viral diarrhea virus based on complete genome and individual gene analyses Spetter, Lucas Maximiliano Louge Uriarte, Enrique Leopoldo Verna, Andrea Elizabeth Odeon, Anselmo Carlos González Altamiranda, Erika Diarrea Viral Bovina Virus Peste Bovina Genomas Bovine Viral Diarrhoea Rinderpestevirus Genomes Bovine viral diarrhea virus (BVDV) genome consists of a single-stranded, positive-sense RNA with high genetic diversity. In the last years, significant progress has been achieved in BVDV knowledge evolution through phylodynamic analysis based on the partial 5′UTR sequences, whereas a few studies have used other genes or the complete coding sequence (CDS). However, no research has evaluated and compared BVDV evolutionary history based on the complete genome (CG), CDS, and individual genes. In this study, phylodynamic analyses were carried out with BVDV-1 (Pestivirus A) and BVDV-2 (Pestivirus B) CG sequences available on the GenBank database and each genomic region: CDS, UTRs, and individual genes. In comparison to the CG, the estimations for both BVDV species varied according to the dataset used, pointing out the importance of considering the analyzed genomic region when concluding. This study may provide new insight into BVDV evolution history while highlighting the need to increase the available BVDV CG sequences to perform more comprehensive phylodynamic studies in the future. EEA Balcarce Fil: Spetter Lucas, Maximiliano Joaquín. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión de Investigaciones Científicas; Arentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil; Argentina Fil: Louge Uriarte, Enrique Leopoldo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina Fil: Verna, Andrea Elizabeth. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina Fil: Odeón, Anselmo Carlos. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina Fil: González Altamiranda, Erika Analia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina 2024-05-09T13:41:19Z 2024-05-09T13:41:19Z 2023-05-23 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/17684 https://link.springer.com/article/10.1007/s42770-023-00986-4 1517-8382(Print) 1678-4405 (Online) https://doi.org/10.1007/s42770-023-00986-4 eng info:eu-repo/semantics/restrictedAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Springer Brazilian Journal of Microbiology 54 : 2461-2469. (May 2023)
spellingShingle Diarrea Viral Bovina
Virus Peste Bovina
Genomas
Bovine Viral Diarrhoea
Rinderpestevirus
Genomes
Spetter, Lucas Maximiliano
Louge Uriarte, Enrique Leopoldo
Verna, Andrea Elizabeth
Odeon, Anselmo Carlos
González Altamiranda, Erika
Genomic evolution of bovine viral diarrhea virus based on complete genome and individual gene analyses
title Genomic evolution of bovine viral diarrhea virus based on complete genome and individual gene analyses
title_full Genomic evolution of bovine viral diarrhea virus based on complete genome and individual gene analyses
title_fullStr Genomic evolution of bovine viral diarrhea virus based on complete genome and individual gene analyses
title_full_unstemmed Genomic evolution of bovine viral diarrhea virus based on complete genome and individual gene analyses
title_short Genomic evolution of bovine viral diarrhea virus based on complete genome and individual gene analyses
title_sort genomic evolution of bovine viral diarrhea virus based on complete genome and individual gene analyses
topic Diarrea Viral Bovina
Virus Peste Bovina
Genomas
Bovine Viral Diarrhoea
Rinderpestevirus
Genomes
url http://hdl.handle.net/20.500.12123/17684
https://link.springer.com/article/10.1007/s42770-023-00986-4
https://doi.org/10.1007/s42770-023-00986-4
work_keys_str_mv AT spetterlucasmaximiliano genomicevolutionofbovineviraldiarrheavirusbasedoncompletegenomeandindividualgeneanalyses
AT lougeuriarteenriqueleopoldo genomicevolutionofbovineviraldiarrheavirusbasedoncompletegenomeandindividualgeneanalyses
AT vernaandreaelizabeth genomicevolutionofbovineviraldiarrheavirusbasedoncompletegenomeandindividualgeneanalyses
AT odeonanselmocarlos genomicevolutionofbovineviraldiarrheavirusbasedoncompletegenomeandindividualgeneanalyses
AT gonzalezaltamirandaerika genomicevolutionofbovineviraldiarrheavirusbasedoncompletegenomeandindividualgeneanalyses