Equine rotavirus a under the one health lens : potential impacts on public health

Group A rotaviruses are a well-known cause of viral gastroenteritis in infants and children, as well as in many mammalian species and birds, affecting them at a young age. This group of viruses has a double-stranded, segmented RNA genome with high genetic diversity linked to point mutations, recombi...

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Autores principales: Carossino, Mariano, Vissani, Maria Aldana, Barrandeguy, Maria Edith, Balasuriya, Udeni B.R., Parreño, Gladys Viviana
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: MDPI 2024
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/17501
https://www.mdpi.com/1999-4915/16/1/130
https://doi.org/10.3390/v16010130
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author Carossino, Mariano
Vissani, Maria Aldana
Barrandeguy, Maria Edith
Balasuriya, Udeni B.R.
Parreño, Gladys Viviana
author_browse Balasuriya, Udeni B.R.
Barrandeguy, Maria Edith
Carossino, Mariano
Parreño, Gladys Viviana
Vissani, Maria Aldana
author_facet Carossino, Mariano
Vissani, Maria Aldana
Barrandeguy, Maria Edith
Balasuriya, Udeni B.R.
Parreño, Gladys Viviana
author_sort Carossino, Mariano
collection INTA Digital
description Group A rotaviruses are a well-known cause of viral gastroenteritis in infants and children, as well as in many mammalian species and birds, affecting them at a young age. This group of viruses has a double-stranded, segmented RNA genome with high genetic diversity linked to point mutations, recombination, and, importantly, reassortment. While initial molecular investigations undertaken in the 1900s suggested host range restriction among group A rotaviruses based on the fact that different gene segments were distributed among different animal species, recent molecular surveillance and genome constellation genotyping studies conducted by the Rotavirus Classification Working Group (RCWG) have shown that animal rotaviruses serve as a source of diversification of human rotavirus A, highlighting their zoonotic potential. Rotaviruses occurring in various animal species have been linked with contributing genetic material to human rotaviruses, including horses, with the most recent identification of equine-like G3 rotavirus A infecting children. The goal of this article is to review relevant information related to rotavirus structure/genomic organization, epidemiology (with a focus on human and equine rotavirus A), evolution, inter-species transmission, and the potential zoonotic role of equine and other animal rotaviruses. Diagnostics, surveillance and the current status of human and livestock vaccines against RVA are also reviewed.
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spelling INTA175012024-04-23T13:35:19Z Equine rotavirus a under the one health lens : potential impacts on public health Carossino, Mariano Vissani, Maria Aldana Barrandeguy, Maria Edith Balasuriya, Udeni B.R. Parreño, Gladys Viviana Rotavirus One Health Approach Public Health Diarrhoea Zoonoses Vaccines Equidae Enfoque Una salud Salud Pública Diarrea Zoonosis Vacuna Group A rotaviruses are a well-known cause of viral gastroenteritis in infants and children, as well as in many mammalian species and birds, affecting them at a young age. This group of viruses has a double-stranded, segmented RNA genome with high genetic diversity linked to point mutations, recombination, and, importantly, reassortment. While initial molecular investigations undertaken in the 1900s suggested host range restriction among group A rotaviruses based on the fact that different gene segments were distributed among different animal species, recent molecular surveillance and genome constellation genotyping studies conducted by the Rotavirus Classification Working Group (RCWG) have shown that animal rotaviruses serve as a source of diversification of human rotavirus A, highlighting their zoonotic potential. Rotaviruses occurring in various animal species have been linked with contributing genetic material to human rotaviruses, including horses, with the most recent identification of equine-like G3 rotavirus A infecting children. The goal of this article is to review relevant information related to rotavirus structure/genomic organization, epidemiology (with a focus on human and equine rotavirus A), evolution, inter-species transmission, and the potential zoonotic role of equine and other animal rotaviruses. Diagnostics, surveillance and the current status of human and livestock vaccines against RVA are also reviewed. Instituto de Virología Fil: Carossino, Mariano. Louisiana State University. School of Veterinary Medicine. Department of Pathobiological Sciences; Estados Unidos Fil: Carossino, Mariano. Louisiana State University. School of Veterinary Medicine. Louisiana Animal Disease Diagnostic Laboratory; Estados Unidos Fil: Vissani, Maria Aldana. Universidad del Salvador. Facultad de Ciencias Agrarias y Veterinarias. Escuela de Veterinaria; Argentina Fil: Vissani, Maria Aldana. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología: Argentina Fil: Vissani, Maria Aldana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Barrandeguy, Maria Edith. Universidad del Salvador. Facultad de Ciencias Agrarias y Veterinarias. Escuela de Veterinaria; Argentina Fil: Barrandeguy, Maria Edith. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina Fil: Balasuriya, Udeni B. R. Louisiana State University. School of Veterinary Medicine. Department of Pathobiological Sciences; Estados Unidos Fil: Balasuriya, Udeni B. R. Louisiana State University. School of Veterinary Medicine. Louisiana Animal Disease Diagnostic Laboratory; Estados Unidos Fil: Parreño, Gladys Viviana. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina Fil: Parreño, Gladys Viviana. Consejo Nacional de Investigaciones Cientificas y Tecnicas; Argentina 2024-04-23T13:29:46Z 2024-04-23T13:29:46Z 2024-01 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/17501 https://www.mdpi.com/1999-4915/16/1/130 1999-4915 https://doi.org/10.3390/v16010130 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf MDPI Viruses 16 (1) : 130 (January 2024)
spellingShingle Rotavirus
One Health Approach
Public Health
Diarrhoea
Zoonoses
Vaccines
Equidae
Enfoque Una salud
Salud Pública
Diarrea
Zoonosis
Vacuna
Carossino, Mariano
Vissani, Maria Aldana
Barrandeguy, Maria Edith
Balasuriya, Udeni B.R.
Parreño, Gladys Viviana
Equine rotavirus a under the one health lens : potential impacts on public health
title Equine rotavirus a under the one health lens : potential impacts on public health
title_full Equine rotavirus a under the one health lens : potential impacts on public health
title_fullStr Equine rotavirus a under the one health lens : potential impacts on public health
title_full_unstemmed Equine rotavirus a under the one health lens : potential impacts on public health
title_short Equine rotavirus a under the one health lens : potential impacts on public health
title_sort equine rotavirus a under the one health lens potential impacts on public health
topic Rotavirus
One Health Approach
Public Health
Diarrhoea
Zoonoses
Vaccines
Equidae
Enfoque Una salud
Salud Pública
Diarrea
Zoonosis
Vacuna
url http://hdl.handle.net/20.500.12123/17501
https://www.mdpi.com/1999-4915/16/1/130
https://doi.org/10.3390/v16010130
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