Non-marine Animal Bioactive Peptides. Properties, Sources, and Applications

Animal proteins and their derivatives play a fundamental role in human nutrition as a source of valuable nutrients and bioactive peptides that have shown an increased interest for their application in the food, pharmaceutical, medicine, and cosmetics industry. In the past years, animal peptides have...

Full description

Bibliographic Details
Main Authors: Chamorro, Verónica Celeste, Pazos, Adriana Alejandra, Báez, Jessica, Fernández-Fernández, Adriana Maite, Medrano, Alejandra
Other Authors: Jafari, Seid Mahdi
Format: Capítulo de libro
Language:Inglés
Published: Springer Nature 2024
Subjects:
Online Access:http://hdl.handle.net/20.500.12123/16903
https://link.springer.com/referenceworkentry/10.1007/978-3-030-81404-5_17-1
https://doi.org/10.1007/978-3-030-81404-5_17-1
_version_ 1855485851867283456
author Chamorro, Verónica Celeste
Pazos, Adriana Alejandra
Báez, Jessica
Fernández-Fernández, Adriana Maite
Medrano, Alejandra
author2 Jafari, Seid Mahdi
author_browse Báez, Jessica
Chamorro, Verónica Celeste
Fernández-Fernández, Adriana Maite
Jafari, Seid Mahdi
Medrano, Alejandra
Pazos, Adriana Alejandra
author_facet Jafari, Seid Mahdi
Chamorro, Verónica Celeste
Pazos, Adriana Alejandra
Báez, Jessica
Fernández-Fernández, Adriana Maite
Medrano, Alejandra
author_sort Chamorro, Verónica Celeste
collection INTA Digital
description Animal proteins and their derivatives play a fundamental role in human nutrition as a source of valuable nutrients and bioactive peptides that have shown an increased interest for their application in the food, pharmaceutical, medicine, and cosmetics industry. In the past years, animal peptides have increased their application in the pharmaceutical industry, due to their great versatility, varied pharmacological functions, high specificity, and low levels of toxicity as well as being natural compounds with minor or no adverse effects when compared to synthetic drugs. Strikingly, only some of the bioactive peptides are sold on the market as functional foods. The possible reason is that most of them do not have sufficient evidence in terms of efficacy and food safety. Additionally, different processing methods may have a certain impact on their bioavailability, affecting their application in food. Therefore, several encapsulation methodologies are being studied in order to protect bioactive peptides, enhance their bioavailability as well as to enhance their sensory and physicochemical properties. This chapter summarizes current knowledge on peptides from meat, milk, and eggs, the main methods of obtaining peptides (enzymatic hydrolysis with commercial proteases, fermentation, and gastrointestinal digestion) and their bioactive properties (antihypertensive and cardiovascular health improvement, antioxidant, antidiabetic, antiobesity, antitumor activity, gut, and neurological health improvement). Moreover, peptide bioaccessibility and bioavailability studies will also be discussed, since these are key factors for these compounds to exert their mechanisms of action in the body. Finally, a discussion about the food applications and perspective studies for promoting animal bioactive peptides use is carried out. In sum, the full set of reported bioactivities plus future research on the efficacy and safety through clinical studies, coupled with the efficient use of byproducts for a sustainable production of these peptides, will reveal the full scope of potential applications of these natural molecules.
format Capítulo de libro
id INTA16903
institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
language Inglés
publishDate 2024
publishDateRange 2024
publishDateSort 2024
publisher Springer Nature
publisherStr Springer Nature
record_format dspace
spelling INTA169032024-03-04T11:26:40Z Non-marine Animal Bioactive Peptides. Properties, Sources, and Applications Chamorro, Verónica Celeste Pazos, Adriana Alejandra Báez, Jessica Fernández-Fernández, Adriana Maite Medrano, Alejandra Jafari, Seid Mahdi By-products Bioactive Properties Bioavailability Subproductos Propiedades Bioactivas Biodisponibilidad Animal Peptides Bioaccessibility Péptidos Animales Bioaccesibilidad Animal proteins and their derivatives play a fundamental role in human nutrition as a source of valuable nutrients and bioactive peptides that have shown an increased interest for their application in the food, pharmaceutical, medicine, and cosmetics industry. In the past years, animal peptides have increased their application in the pharmaceutical industry, due to their great versatility, varied pharmacological functions, high specificity, and low levels of toxicity as well as being natural compounds with minor or no adverse effects when compared to synthetic drugs. Strikingly, only some of the bioactive peptides are sold on the market as functional foods. The possible reason is that most of them do not have sufficient evidence in terms of efficacy and food safety. Additionally, different processing methods may have a certain impact on their bioavailability, affecting their application in food. Therefore, several encapsulation methodologies are being studied in order to protect bioactive peptides, enhance their bioavailability as well as to enhance their sensory and physicochemical properties. This chapter summarizes current knowledge on peptides from meat, milk, and eggs, the main methods of obtaining peptides (enzymatic hydrolysis with commercial proteases, fermentation, and gastrointestinal digestion) and their bioactive properties (antihypertensive and cardiovascular health improvement, antioxidant, antidiabetic, antiobesity, antitumor activity, gut, and neurological health improvement). Moreover, peptide bioaccessibility and bioavailability studies will also be discussed, since these are key factors for these compounds to exert their mechanisms of action in the body. Finally, a discussion about the food applications and perspective studies for promoting animal bioactive peptides use is carried out. In sum, the full set of reported bioactivities plus future research on the efficacy and safety through clinical studies, coupled with the efficient use of byproducts for a sustainable production of these peptides, will reveal the full scope of potential applications of these natural molecules. Las proteínas animales y sus derivados juegan un papel fundamental en la nutrición humana como fuente de valiosos nutrientes y péptidos bioactivos que han demostrado un creciente interés por su aplicación en los sectores alimentario, farmacéutico, medicinal, y la industria cosmética. En los últimos años, los péptidos animales han aumentado su aplicación en el industria farmacéutica, debido a su gran versatilidad, variados tratamientos farmacológicos. Funciones, alta especificidad y bajos niveles de toxicidad, además de ser natural. compuestos con efectos adversos menores o nulos en comparación con los sintéticos drogas. Sorprendentemente, sólo algunos de los péptidos bioactivos se venden en el mercado. como alimentos funcionales. La posible razón es que la mayoría de ellos no tienen evidencia suficiente en términos de eficacia y seguridad alimentaria. Además, diferentes Los métodos de procesamiento pueden tener un cierto impacto en su biodisponibilidad, afectando su aplicación en alimentos. Por lo tanto, varias metodologías de encapsulación se están estudiando para proteger los péptidos bioactivos y mejorar su biodisponibilidad así como potenciar sus propiedades sensoriales y fisicoquímicas. Este capítulo resume el conocimiento actual sobre los péptidos de la carne, la leche y huevos, los principales métodos de obtención de péptidos (hidrólisis enzimática con productos comerciales proteasas, fermentación y digestión gastrointestinal) y sus bioactivos. propiedades (antihipertensivas y de mejora de la salud cardiovascular, antioxidante, antidiabético, antiobesidad, actividad antitumoral, intestinal y neurológica mejora de la salud). Además, estudios de bioaccesibilidad y biodisponibilidad de péptidos. También se discutirá, ya que estos son factores clave para que estos compuestos ejerzan sus mecanismos de acción en el organismo. Finalmente, una discusión sobre la comida. Aplicaciones y estudios de perspectiva para promover el uso de péptidos bioactivos animales. se lleva a cabo. En resumen, el conjunto completo de bioactividades reportadas más investigaciones futuras sobre la eficacia y seguridad a través de estudios clínicos, junto con el uso eficiente de subproductos para una producción sostenible de estos péptidos, revelará el alcance completo de Aplicaciones potenciales de estas moléculas naturales. Instituto de Investigación de Tecnología de Alimentos (ITA) Fil: Chamorro, Verónica Celeste. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación Tecnología de Alimentos; Argentina. Fil: Chamorro, Verónica Celeste. Instituto de Ciencia y Tecnología de los Sistemas Alimentarios Sustentables (ICyTeSAS) UEDD INTA-CONICET; Argentina Fil: Pazos, Adriana Alejandra. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación Tecnología de Alimentos; Argentina. Fil: Pazos, Adriana Alejandra. Instituto de Ciencia y Tecnología de los Sistemas Alimentarios Sustentables (ICyTeSAS) UEDD INTA-CONICET; Argentina. Fil: Pazos, Adriana Alejandra. Universidad de Morón. Facultad de Agronomía y Ciencias Agroalimentarias; Argentina. Fil: Báez, Jessica. Universidad de la República. Facultad de Química. Departamento de Ciencia y Tecnología de Alimentos; Uruguay. Fil: Fernández-Fernández, Adriana Maite. Universidad de la República. Facultad de Química. Departamento de Ciencia y Tecnología de Alimentos; Uruguay. Fil: Medrano, Alejandra. Universidad de la República. Facultad de Química. Departamento de Ciencia y Tecnología de Alimentos; Uruguay. 2024-03-04T11:14:20Z 2024-03-04T11:14:20Z 2023-06 info:ar-repo/semantics/parte de libro info:eu-repo/semantics/bookPart info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/16903 https://link.springer.com/referenceworkentry/10.1007/978-3-030-81404-5_17-1 978-3-030-81404-5 (e-book) https://doi.org/10.1007/978-3-030-81404-5_17-1 eng info:eu-repo/semantics/restrictedAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Springer Nature Handbook of Food Bioactive Ingredients. Properties and Applications. / editors: Seid Mahdi Jafari, Ali Rashidinejad, Jesus Simal-Gandara. Suiza: Springer, 2023. p 1-38.
spellingShingle By-products
Bioactive Properties
Bioavailability
Subproductos
Propiedades Bioactivas
Biodisponibilidad
Animal Peptides
Bioaccessibility
Péptidos Animales
Bioaccesibilidad
Chamorro, Verónica Celeste
Pazos, Adriana Alejandra
Báez, Jessica
Fernández-Fernández, Adriana Maite
Medrano, Alejandra
Non-marine Animal Bioactive Peptides. Properties, Sources, and Applications
title Non-marine Animal Bioactive Peptides. Properties, Sources, and Applications
title_full Non-marine Animal Bioactive Peptides. Properties, Sources, and Applications
title_fullStr Non-marine Animal Bioactive Peptides. Properties, Sources, and Applications
title_full_unstemmed Non-marine Animal Bioactive Peptides. Properties, Sources, and Applications
title_short Non-marine Animal Bioactive Peptides. Properties, Sources, and Applications
title_sort non marine animal bioactive peptides properties sources and applications
topic By-products
Bioactive Properties
Bioavailability
Subproductos
Propiedades Bioactivas
Biodisponibilidad
Animal Peptides
Bioaccessibility
Péptidos Animales
Bioaccesibilidad
url http://hdl.handle.net/20.500.12123/16903
https://link.springer.com/referenceworkentry/10.1007/978-3-030-81404-5_17-1
https://doi.org/10.1007/978-3-030-81404-5_17-1
work_keys_str_mv AT chamorroveronicaceleste nonmarineanimalbioactivepeptidespropertiessourcesandapplications
AT pazosadrianaalejandra nonmarineanimalbioactivepeptidespropertiessourcesandapplications
AT baezjessica nonmarineanimalbioactivepeptidespropertiessourcesandapplications
AT fernandezfernandezadrianamaite nonmarineanimalbioactivepeptidespropertiessourcesandapplications
AT medranoalejandra nonmarineanimalbioactivepeptidespropertiessourcesandapplications