Quantitative microbial risk assessment of haemolytic uremic syndrome associated with Argentinean kosher beef consumption in Israel
The aim of this study was to perform a quantitative microbial risk assessment (QMRA) of Shiga toxin-producing Escherichia coli hemolytic uremic syndrome (STEC-HUS) linked to the consumption of Kosher beef produced in Argentina and consumed in Israel in children under 14 years. A probabilistic risk a...
| Autores principales: | , , , |
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| Formato: | info:ar-repo/semantics/artículo |
| Lenguaje: | Inglés |
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Plos ONE
2024
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12123/16793 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0290182 https://doi.org/10.1371/journal.pone.0290182 |
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| author | Brusa, Victoria Dolev, Sergio Signorini Porchiett, Marcelo Lisandro Leotta, Gerardo Anibal |
| author_browse | Brusa, Victoria Dolev, Sergio Leotta, Gerardo Anibal Signorini Porchiett, Marcelo Lisandro |
| author_facet | Brusa, Victoria Dolev, Sergio Signorini Porchiett, Marcelo Lisandro Leotta, Gerardo Anibal |
| author_sort | Brusa, Victoria |
| collection | INTA Digital |
| description | The aim of this study was to perform a quantitative microbial risk assessment (QMRA) of Shiga toxin-producing Escherichia coli hemolytic uremic syndrome (STEC-HUS) linked to the consumption of Kosher beef produced in Argentina and consumed in Israel in children under 14 years. A probabilistic risk assessment model was developed to characterize STEC prevalence and contamination levels in the beef supply chain (cattle primary production, cattle transport, processing and storage in the abattoir, for export and at retail, and home preparation and consumption). The model was implemented in Microsoft Excel 2016 with the @Risk add-on package. Results of 302 surveys with data collected in Israel were as follows: 92.3% of people consumed beef, mostly at home, and 98.2% preferred levels of cooking that ensured STEC removal from the surface of beef cuts. The preferred degree of ground beef doneness was “well-done” (48.2%). Cooking preference ranged from red to “medium-well done” (51.8%). Median HUS probability from Argentinean beef cut and ground beef consumption in children under 14 years old was <10−15 and 8.57x10-10, respectively. The expected average annual number of HUS cases and deaths due to beef cut and ground beef consumption was zero. Risk of infection and HUS probability correlated with salting effect on E. coli count, processing raw beef before vegetables, ways of storage and refrigeration temperature at home, joint consumption of salad and beef cuts, degree of beef doneness and cutting board washing with detergent after each use with beef and vegetables. The STEC-HUS risk in Israel from consumption of bovine beef produced in Argentina was negligible. The current QMRA results were similar to those of previous beef cut consumption QMRA in Argentina and lower than any of the QMRA performed worldwide in other STEC-HUS linked to ground beef consumption. This study confirms the importance of QMRA to estimate and manage the risk of STEC-HUS from beef consumption. The impact variables identified in the sensitivity analysis allowed us to optimize resources and time management, to focus on accurate actions and to avoid taking measures that would not have an impact on the risk of STEC-HUS. |
| format | info:ar-repo/semantics/artículo |
| id | INTA16793 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | Plos ONE |
| publisherStr | Plos ONE |
| record_format | dspace |
| spelling | INTA167932024-02-26T11:13:09Z Quantitative microbial risk assessment of haemolytic uremic syndrome associated with Argentinean kosher beef consumption in Israel Brusa, Victoria Dolev, Sergio Signorini Porchiett, Marcelo Lisandro Leotta, Gerardo Anibal Carne de Res Evaluación de Riesgos Anemia Hemolítica Argentina Israel Enfermedades Humanas Beef Risk Assessment Haemolytic Anaemia Human Diseases Síndrome Urémico Hemolítico Carne Kosher Haemolytic Uremic Syndrome Kosher Beef The aim of this study was to perform a quantitative microbial risk assessment (QMRA) of Shiga toxin-producing Escherichia coli hemolytic uremic syndrome (STEC-HUS) linked to the consumption of Kosher beef produced in Argentina and consumed in Israel in children under 14 years. A probabilistic risk assessment model was developed to characterize STEC prevalence and contamination levels in the beef supply chain (cattle primary production, cattle transport, processing and storage in the abattoir, for export and at retail, and home preparation and consumption). The model was implemented in Microsoft Excel 2016 with the @Risk add-on package. Results of 302 surveys with data collected in Israel were as follows: 92.3% of people consumed beef, mostly at home, and 98.2% preferred levels of cooking that ensured STEC removal from the surface of beef cuts. The preferred degree of ground beef doneness was “well-done” (48.2%). Cooking preference ranged from red to “medium-well done” (51.8%). Median HUS probability from Argentinean beef cut and ground beef consumption in children under 14 years old was <10−15 and 8.57x10-10, respectively. The expected average annual number of HUS cases and deaths due to beef cut and ground beef consumption was zero. Risk of infection and HUS probability correlated with salting effect on E. coli count, processing raw beef before vegetables, ways of storage and refrigeration temperature at home, joint consumption of salad and beef cuts, degree of beef doneness and cutting board washing with detergent after each use with beef and vegetables. The STEC-HUS risk in Israel from consumption of bovine beef produced in Argentina was negligible. The current QMRA results were similar to those of previous beef cut consumption QMRA in Argentina and lower than any of the QMRA performed worldwide in other STEC-HUS linked to ground beef consumption. This study confirms the importance of QMRA to estimate and manage the risk of STEC-HUS from beef consumption. The impact variables identified in the sensitivity analysis allowed us to optimize resources and time management, to focus on accurate actions and to avoid taking measures that would not have an impact on the risk of STEC-HUS. EEA Rafaela Fil: Brusa, Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout"; Argentina Fil: Brusa, Victoria. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina. Fil: Dolev, Sergio. Ministry of Agriculture and Rural Development. Veterinary Services and Animal Health; Israel Fil: Signorini, Marcelo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela. Instituto de Investigación de la Cadena Láctea (IDICAL); Argentina Fil: Signorini, Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación de la Cadena Láctea (IDICAL); Argentina Fil: Leotta, Gerardo Anibal. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Ciencia y Tecnología de Sistemas Alimentarios Sustentables; Argentina Fil: Leotta, Gerardo Anibal. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Ciencia y Tecnología de Sistemas Alimentarios Sustentables; Argentina 2024-02-26T11:11:06Z 2024-02-26T11:11:06Z 2023-08 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/16793 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0290182 1932-6203 https://doi.org/10.1371/journal.pone.0290182 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Plos ONE PLoS ONE 18 (8) : e0290182. (2023) |
| spellingShingle | Carne de Res Evaluación de Riesgos Anemia Hemolítica Argentina Israel Enfermedades Humanas Beef Risk Assessment Haemolytic Anaemia Human Diseases Síndrome Urémico Hemolítico Carne Kosher Haemolytic Uremic Syndrome Kosher Beef Brusa, Victoria Dolev, Sergio Signorini Porchiett, Marcelo Lisandro Leotta, Gerardo Anibal Quantitative microbial risk assessment of haemolytic uremic syndrome associated with Argentinean kosher beef consumption in Israel |
| title | Quantitative microbial risk assessment of haemolytic uremic syndrome associated with Argentinean kosher beef consumption in Israel |
| title_full | Quantitative microbial risk assessment of haemolytic uremic syndrome associated with Argentinean kosher beef consumption in Israel |
| title_fullStr | Quantitative microbial risk assessment of haemolytic uremic syndrome associated with Argentinean kosher beef consumption in Israel |
| title_full_unstemmed | Quantitative microbial risk assessment of haemolytic uremic syndrome associated with Argentinean kosher beef consumption in Israel |
| title_short | Quantitative microbial risk assessment of haemolytic uremic syndrome associated with Argentinean kosher beef consumption in Israel |
| title_sort | quantitative microbial risk assessment of haemolytic uremic syndrome associated with argentinean kosher beef consumption in israel |
| topic | Carne de Res Evaluación de Riesgos Anemia Hemolítica Argentina Israel Enfermedades Humanas Beef Risk Assessment Haemolytic Anaemia Human Diseases Síndrome Urémico Hemolítico Carne Kosher Haemolytic Uremic Syndrome Kosher Beef |
| url | http://hdl.handle.net/20.500.12123/16793 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0290182 https://doi.org/10.1371/journal.pone.0290182 |
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