Quantitative trait loci exploration and characterization of gestation length in Holstein cattle
Gestation length (GL) is a moderately heritable trait in cattle with economic and management implications. This study aimed to characterize the gestation length of an Argentinian Holstein cattle population, understand contributing factors, and explore the GL effect on production performance. Further...
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| Format: | Artículo |
| Language: | Inglés |
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Elsevier
2023
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| Online Access: | http://hdl.handle.net/20.500.12123/16181 https://www.sciencedirect.com/science/article/pii/S0093691X23004454 https://doi.org/10.1016/j.theriogenology.2023.11.012 |
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| author | Raschia, Maria Agustina Maizon, Daniel Omar Amadio, Ariel Nani, Juan Pablo Poli, Mario Andres |
| author_browse | Amadio, Ariel Maizon, Daniel Omar Nani, Juan Pablo Poli, Mario Andres Raschia, Maria Agustina |
| author_facet | Raschia, Maria Agustina Maizon, Daniel Omar Amadio, Ariel Nani, Juan Pablo Poli, Mario Andres |
| author_sort | Raschia, Maria Agustina |
| collection | INTA Digital |
| description | Gestation length (GL) is a moderately heritable trait in cattle with economic and management implications. This study aimed to characterize the gestation length of an Argentinian Holstein cattle population, understand contributing factors, and explore the GL effect on production performance. Further objectives were to estimate direct and maternal heritabilities for this trait and to identify genomic regions affecting it. Data consisted of GL records from 45,738 births corresponding to 17,004 Holstein cows and heifers. The effects of age and calving season over GL were analyzed using a Student's t-test for homoscedastic samples. The effects of the GL category (GL shorter than 1.5 SD, within ±1.5 SD, and longer than 1.5 SD from the mean) on production performance were studied by analysis of variance. A single-step genome-wide association study was performed using the BLUPF90 suite of programs with genotypes from 654 Holstein animals on 40,339 SNP. The results showed that the younger the age at calving, the shorter the GL. Moreover, gestations ending in warmer seasons were, in general, statistically shorter than those ending in colder seasons for both heifers and cows. Regarding the effect of GL on production performance, cows with gestation periods within ±1.5 SD from the population mean exhibited the highest 305-day cumulative milk, fat, and protein productions. Direct and maternal heritabilities for GL were 0.42 and 0.03, respectively. We detected a SNP suggestively associated with direct gestation length at 57.7 Mb on Bos taurus autosome 18, a locus included in a region described in the literature as associated with the trait. The information obtained on the environmental and genetic factors affecting GL in Argentinian Holstein cows contributes to characterizing the population in pursuit of improving the performance of national dairy cattle breeding systems. |
| format | Artículo |
| id | INTA16181 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | INTA161812023-12-12T09:55:22Z Quantitative trait loci exploration and characterization of gestation length in Holstein cattle Raschia, Maria Agustina Maizon, Daniel Omar Amadio, Ariel Nani, Juan Pablo Poli, Mario Andres Gestation Period Genome-wide Association Studies Quantitative Trait Loci Heritability Dairy Cows Dairy Cattle Período de Gestación Estudios de Asociación del Genoma Completo Loci de Rasgos Cuantitativos Heredabilidad Vacas Lecheras Ganado de Leche Raza Holstein Gestation length (GL) is a moderately heritable trait in cattle with economic and management implications. This study aimed to characterize the gestation length of an Argentinian Holstein cattle population, understand contributing factors, and explore the GL effect on production performance. Further objectives were to estimate direct and maternal heritabilities for this trait and to identify genomic regions affecting it. Data consisted of GL records from 45,738 births corresponding to 17,004 Holstein cows and heifers. The effects of age and calving season over GL were analyzed using a Student's t-test for homoscedastic samples. The effects of the GL category (GL shorter than 1.5 SD, within ±1.5 SD, and longer than 1.5 SD from the mean) on production performance were studied by analysis of variance. A single-step genome-wide association study was performed using the BLUPF90 suite of programs with genotypes from 654 Holstein animals on 40,339 SNP. The results showed that the younger the age at calving, the shorter the GL. Moreover, gestations ending in warmer seasons were, in general, statistically shorter than those ending in colder seasons for both heifers and cows. Regarding the effect of GL on production performance, cows with gestation periods within ±1.5 SD from the population mean exhibited the highest 305-day cumulative milk, fat, and protein productions. Direct and maternal heritabilities for GL were 0.42 and 0.03, respectively. We detected a SNP suggestively associated with direct gestation length at 57.7 Mb on Bos taurus autosome 18, a locus included in a region described in the literature as associated with the trait. The information obtained on the environmental and genetic factors affecting GL in Argentinian Holstein cows contributes to characterizing the population in pursuit of improving the performance of national dairy cattle breeding systems. Instituto de Genética Fil: Raschia, Maria Agustina. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Genética; Argentina Fil: Maizon, Daniel Omar. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil; Argentina Fil: Amadio, Ariel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina Fil: Amadio, Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Nani, Juan Pablo. ABS Global; Estados Unidos Fil: Poli, Mario Andres. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Genética; Argentina Fil: Poli, Mario Andres. Universidad del Salvador. Facultad de Ciencias Agrarias y Veterinaria; Argentina 2023-12-12T09:42:44Z 2023-12-12T09:42:44Z 2024-02 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/16181 https://www.sciencedirect.com/science/article/pii/S0093691X23004454 1879-3231 https://doi.org/10.1016/j.theriogenology.2023.11.012 eng info:eu-repograntAgreement/INTA/2019-PE-E6-I145-001, Mejora genética objetiva para aumentar la eficiencia de los sistemas de producción animal info:eu-repograntAgreement/INTA/2019-PE-E6-I114-001, Caracterización de la diversidad genética de plantas, animales y microorganismos mediante herramientas de genómica aplicada info:eu-repograntAgreement/INTA/2019-PD-E5-I107-001, Biotecnologías de la reproducción: mejora de la eficiencia reproductiva en especies de interés zootécnico info:eu-repograntAgreement/INTA/2019-PE-E1-I018-001, Crecimiento del rodeo lechero (crianza, recría y manejo en el primer estadio de la lactancia) info:eu-repograntAgreement/INTA/2023-PD-L01-I108, Mejora genética animal en la era de la genómica y la ganadería inteligente: adaptación y resiliencia info:eu-repograntAgreement/INTA/2019-RIST-E6-I112-001, Red de Recursos Genéticos info:eu-repograntAgreement/INTA/2023-PD-L01-I087, Caracterización de la diversidad genética de plantas, animales y microorganismos mediante herramientas de genómica aplicada. info:eu-repo/semantics/restrictedAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Elsevier Theriogenology 215 : 43-49. (February 2024) |
| spellingShingle | Gestation Period Genome-wide Association Studies Quantitative Trait Loci Heritability Dairy Cows Dairy Cattle Período de Gestación Estudios de Asociación del Genoma Completo Loci de Rasgos Cuantitativos Heredabilidad Vacas Lecheras Ganado de Leche Raza Holstein Raschia, Maria Agustina Maizon, Daniel Omar Amadio, Ariel Nani, Juan Pablo Poli, Mario Andres Quantitative trait loci exploration and characterization of gestation length in Holstein cattle |
| title | Quantitative trait loci exploration and characterization of gestation length in Holstein cattle |
| title_full | Quantitative trait loci exploration and characterization of gestation length in Holstein cattle |
| title_fullStr | Quantitative trait loci exploration and characterization of gestation length in Holstein cattle |
| title_full_unstemmed | Quantitative trait loci exploration and characterization of gestation length in Holstein cattle |
| title_short | Quantitative trait loci exploration and characterization of gestation length in Holstein cattle |
| title_sort | quantitative trait loci exploration and characterization of gestation length in holstein cattle |
| topic | Gestation Period Genome-wide Association Studies Quantitative Trait Loci Heritability Dairy Cows Dairy Cattle Período de Gestación Estudios de Asociación del Genoma Completo Loci de Rasgos Cuantitativos Heredabilidad Vacas Lecheras Ganado de Leche Raza Holstein |
| url | http://hdl.handle.net/20.500.12123/16181 https://www.sciencedirect.com/science/article/pii/S0093691X23004454 https://doi.org/10.1016/j.theriogenology.2023.11.012 |
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