Effects of Mixed Baculovirus Infections in Biological Control: A Comprehensive Historical and Technical Analysis
Baculoviruses are insect-specific DNA viruses that have been exploited as bioinsecticides for the control of agricultural and forest pests around the world. Mixed infections with two different baculoviruses have been found in nature, infecting the same host. They have been studied to understand the...
| Main Authors: | , |
|---|---|
| Format: | Artículo |
| Language: | Inglés |
| Published: |
Multidisciplinary Digital Publishing Institute (MDPI)
2023
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.12123/16170 https://www.mdpi.com/1999-4915/15/9/1838 https://doi.org/10.3390/v15091838 |
| _version_ | 1855485702996754432 |
|---|---|
| author | Ferrelli, María Leticia Salvador, Ricardo |
| author_browse | Ferrelli, María Leticia Salvador, Ricardo |
| author_facet | Ferrelli, María Leticia Salvador, Ricardo |
| author_sort | Ferrelli, María Leticia |
| collection | INTA Digital |
| description | Baculoviruses are insect-specific DNA viruses that have been exploited as bioinsecticides for the control of agricultural and forest pests around the world. Mixed infections with two different baculoviruses have been found in nature, infecting the same host. They have been studied to understand the biology of virus interactions, their effects on susceptible insects, and their insecticidal implications. In this work, we summarize and analyze the in vivo baculovirus co-infections reported in the literature, mainly focusing on pest biocontrol applications. We discuss the most common terms used to describe the effects of mixed infections, such as synergism, neutralism, and antagonism, and how to determine them based on host mortality. Frequently, baculovirus co-infections found in nature are caused by a combination of a nucleopolyhedrovirus and a granulovirus. Studies performed with mixed infections indicated that viral dose, larval stage, or the presence of synergistic factors in baculovirus occlusion bodies are important for the type of virus interaction. We also enumerate and discuss technical aspects to take into account in studies on mixed infections, such as statistical procedures, quantification of viral inocula, the selection of instars, and molecular methodologies for an appropriate analysis of baculovirus interaction. Several experimental infections using two different baculoviruses demonstrated increased viral mortality or a synergistic effect on the target larvae compared to single infections. This can be exploited to improve the baculovirus-killing properties of commercial formulations. In this work, we offer a current overview of baculovirus interactions in vivo and discuss their potential applications in pest control strategies. |
| format | Artículo |
| id | INTA16170 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | Multidisciplinary Digital Publishing Institute (MDPI) |
| publisherStr | Multidisciplinary Digital Publishing Institute (MDPI) |
| record_format | dspace |
| spelling | INTA161702023-12-11T11:24:48Z Effects of Mixed Baculovirus Infections in Biological Control: A Comprehensive Historical and Technical Analysis Ferrelli, María Leticia Salvador, Ricardo Biological Control Pest Control Synergism Antagonism Additive Effect Control Biológico Sinergismo Baculovirus Control de Plagas Antagonismo Efecto Aditivo Bioinsecticidas Baculoviruses are insect-specific DNA viruses that have been exploited as bioinsecticides for the control of agricultural and forest pests around the world. Mixed infections with two different baculoviruses have been found in nature, infecting the same host. They have been studied to understand the biology of virus interactions, their effects on susceptible insects, and their insecticidal implications. In this work, we summarize and analyze the in vivo baculovirus co-infections reported in the literature, mainly focusing on pest biocontrol applications. We discuss the most common terms used to describe the effects of mixed infections, such as synergism, neutralism, and antagonism, and how to determine them based on host mortality. Frequently, baculovirus co-infections found in nature are caused by a combination of a nucleopolyhedrovirus and a granulovirus. Studies performed with mixed infections indicated that viral dose, larval stage, or the presence of synergistic factors in baculovirus occlusion bodies are important for the type of virus interaction. We also enumerate and discuss technical aspects to take into account in studies on mixed infections, such as statistical procedures, quantification of viral inocula, the selection of instars, and molecular methodologies for an appropriate analysis of baculovirus interaction. Several experimental infections using two different baculoviruses demonstrated increased viral mortality or a synergistic effect on the target larvae compared to single infections. This can be exploited to improve the baculovirus-killing properties of commercial formulations. In this work, we offer a current overview of baculovirus interactions in vivo and discuss their potential applications in pest control strategies. Instituto de Microbiología y Zoología Agrícola (IMYZA) Fil: Ferrelli, Maria Leticia. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Biotecnología y Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biotecnología y Biología Molecular; Argentina Fil: Salvador, Ricardo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Microbiología y Zoología Agrícola; Argentina 2023-12-11T11:04:22Z 2023-12-11T11:04:22Z 2023-08-30 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/16170 https://www.mdpi.com/1999-4915/15/9/1838 1999-4915 https://doi.org/10.3390/v15091838 eng info:eu-repograntAgreement/INTA/2023-PE-L04-I073, Desarrollo de bioinsumos y su integración en estrategias de manejo de adversidades bióticas y abióticas en cultivos agrícolas y forestales info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Multidisciplinary Digital Publishing Institute (MDPI) Viruses 15 (9) : 1838 (Agosto 2023) |
| spellingShingle | Biological Control Pest Control Synergism Antagonism Additive Effect Control Biológico Sinergismo Baculovirus Control de Plagas Antagonismo Efecto Aditivo Bioinsecticidas Ferrelli, María Leticia Salvador, Ricardo Effects of Mixed Baculovirus Infections in Biological Control: A Comprehensive Historical and Technical Analysis |
| title | Effects of Mixed Baculovirus Infections in Biological Control: A Comprehensive Historical and Technical Analysis |
| title_full | Effects of Mixed Baculovirus Infections in Biological Control: A Comprehensive Historical and Technical Analysis |
| title_fullStr | Effects of Mixed Baculovirus Infections in Biological Control: A Comprehensive Historical and Technical Analysis |
| title_full_unstemmed | Effects of Mixed Baculovirus Infections in Biological Control: A Comprehensive Historical and Technical Analysis |
| title_short | Effects of Mixed Baculovirus Infections in Biological Control: A Comprehensive Historical and Technical Analysis |
| title_sort | effects of mixed baculovirus infections in biological control a comprehensive historical and technical analysis |
| topic | Biological Control Pest Control Synergism Antagonism Additive Effect Control Biológico Sinergismo Baculovirus Control de Plagas Antagonismo Efecto Aditivo Bioinsecticidas |
| url | http://hdl.handle.net/20.500.12123/16170 https://www.mdpi.com/1999-4915/15/9/1838 https://doi.org/10.3390/v15091838 |
| work_keys_str_mv | AT ferrellimarialeticia effectsofmixedbaculovirusinfectionsinbiologicalcontrolacomprehensivehistoricalandtechnicalanalysis AT salvadorricardo effectsofmixedbaculovirusinfectionsinbiologicalcontrolacomprehensivehistoricalandtechnicalanalysis |