Virulence genes and antimicrobial susceptibility in Salmonella enterica serotypes isolated from swine production in Argentina = Genes de virulencia y sensibilidad a antimicrobianos en serotipos de Salmonella enterica aislados de producción porcina en Argentina
Salmonella is a worldwide-distributed pathogen that affects both humans and animals and is usually associated with intensive animal production such as poultry and swine. This bacterium carries different virulence genes, whose expression favors its interaction with the host and may influence the cour...
| Autores principales: | , , , |
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| Formato: | Artículo |
| Lenguaje: | Inglés |
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Elsevier
2023
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| Acceso en línea: | http://hdl.handle.net/20.500.12123/16101 https://www.sciencedirect.com/science/article/pii/S0325754120300973 https://doi.org/10.1016/j.ram.2020.10.001 |
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| author | Joaquim, Patricia Estefania Herrera, Mariana Dupuis, Alberto Chacana, Pablo |
| author_browse | Chacana, Pablo Dupuis, Alberto Herrera, Mariana Joaquim, Patricia Estefania |
| author_facet | Joaquim, Patricia Estefania Herrera, Mariana Dupuis, Alberto Chacana, Pablo |
| author_sort | Joaquim, Patricia Estefania |
| collection | INTA Digital |
| description | Salmonella is a worldwide-distributed pathogen that affects both humans and animals and is usually associated with intensive animal production such as poultry and swine. This bacterium carries different virulence genes, whose expression favors its interaction with the host and may influence the course of the infection. Extended usage of antibiotics for metaphylaxis or prophylaxis and as growth promoters favors the emergence of multiresistant Salmonella strains. The aim of this work was to assess the association between the presence of virulence-associated genes and the antimicrobial resistance phenotype in Salmonella isolates obtained from swine intensive and backyard farms in Argentina during 2012–2018. A total of 59 Salmonella strains belonging to several serotypes were studied. All the strains carried the sopB and ssaQ genes, whereas more than 90% of the isolates carried the mgtC, avrA, and siiD genes. Some isolates also carried the bcfC, sodC1, gipA, sopE1 and spvC genes; however, their presence varied among them. Susceptibility to the antibiotics tested was diverse. Isolates from intensive farms were resistant to a larger number of antimicrobials than those from backyard farms and some of the strains showed high virulence potential and extensive antimicrobial resistance profiles. Continuous surveillance is essential to detect the emergence of strains that may represent a significant risk not only for animal production but also for the human population. |
| format | Artículo |
| id | INTA16101 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | INTA161012023-12-01T18:59:27Z Virulence genes and antimicrobial susceptibility in Salmonella enterica serotypes isolated from swine production in Argentina = Genes de virulencia y sensibilidad a antimicrobianos en serotipos de Salmonella enterica aislados de producción porcina en Argentina Joaquim, Patricia Estefania Herrera, Mariana Dupuis, Alberto Chacana, Pablo Salmonella Swine Antimicrobial Resistance Virulence Genes Cerdo Resistencia a los Antimicrobianos Virulencia Salmonella is a worldwide-distributed pathogen that affects both humans and animals and is usually associated with intensive animal production such as poultry and swine. This bacterium carries different virulence genes, whose expression favors its interaction with the host and may influence the course of the infection. Extended usage of antibiotics for metaphylaxis or prophylaxis and as growth promoters favors the emergence of multiresistant Salmonella strains. The aim of this work was to assess the association between the presence of virulence-associated genes and the antimicrobial resistance phenotype in Salmonella isolates obtained from swine intensive and backyard farms in Argentina during 2012–2018. A total of 59 Salmonella strains belonging to several serotypes were studied. All the strains carried the sopB and ssaQ genes, whereas more than 90% of the isolates carried the mgtC, avrA, and siiD genes. Some isolates also carried the bcfC, sodC1, gipA, sopE1 and spvC genes; however, their presence varied among them. Susceptibility to the antibiotics tested was diverse. Isolates from intensive farms were resistant to a larger number of antimicrobials than those from backyard farms and some of the strains showed high virulence potential and extensive antimicrobial resistance profiles. Continuous surveillance is essential to detect the emergence of strains that may represent a significant risk not only for animal production but also for the human population. Salmonella es un patógeno de distribución mundial, que afecta tanto a humanos como a animales, y generalmente está asociado a la producción animal intensiva, entre ellas, la aviar y la porcina. Esta bacteria contiene diferentes genes de virulencia, cuya expresión favorece su interacción con el huésped y puede influir en el curso de la infección. El uso extendido de antibióticos en forma metafiláctica o profiláctica, o como promotores del crecimiento, favorece la aparición de cepas de Salmonella multirresistentes. El objetivo de este trabajo fue determinar la presencia de genes de virulencia y la sensibilidad a antimicrobianos en cepas de Salmonella aisladas en producciones porcinas intensivas y de traspatio de la República Argentina entre los años 2012 y 2018. Se estudiaron un total de 59 aislamientos de Salmonella pertenecientes a distintos serotipos. Todos los aislamientos presentaron los genes sopB y ssaQ, mientras que más del 90% portaron los genes mgtC, avrA y siiD. Algunos aislamientos también fueron positivos para los genes bcfC, sodC1, gipA, sopE1 y spvC, pero su presencia fue variable entre las cepas analizadas. La sensibilidad a los antibióticos evaluados fue diversa. Los aislamientos de granjas intensivas fueron resistentes a un mayor número de antimicrobianos que los de granjas de traspatio y algunas de las cepas mostraron perfiles con un alto potencial de virulencia, así como resistencia extendida a antimicrobianos. La vigilancia continua es esencial para detectar la aparición de este tipo de cepas, que pueden representar un riesgo significativo no solo para la producción animal, sino también para la población humana. Instituto de Patobiología Fil: Joaquim, Patricia Estefania. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología Veterinaria; Argentina Fil: Joaquim, Patricia Estefania. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Herrera, Mariana. Servicio Nacional de Sanidad y Calidad Agroalimentaria (SENASA). Dirección General de Laboratorios y Control Técnico (DILAB); Argentina Fil: Dupuis, Alberto. Servicio Nacional de Sanidad y Calidad Agroalimentaria (SENASA). Dirección General de Laboratorios y Control Técnico (DILAB); Argentina Fil: Chacana, Pablo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología Veterinaria; Argentina Fil: Chacana, Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina 2023-12-01T18:47:23Z 2023-12-01T18:47:23Z 2021 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/16101 https://www.sciencedirect.com/science/article/pii/S0325754120300973 0325-7541 https://doi.org/10.1016/j.ram.2020.10.001 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Elsevier Revista Argentina de Microbiología 53 (3) : 233-239 (Julio-septiembre 2021) |
| spellingShingle | Salmonella Swine Antimicrobial Resistance Virulence Genes Cerdo Resistencia a los Antimicrobianos Virulencia Joaquim, Patricia Estefania Herrera, Mariana Dupuis, Alberto Chacana, Pablo Virulence genes and antimicrobial susceptibility in Salmonella enterica serotypes isolated from swine production in Argentina = Genes de virulencia y sensibilidad a antimicrobianos en serotipos de Salmonella enterica aislados de producción porcina en Argentina |
| title | Virulence genes and antimicrobial susceptibility in Salmonella enterica serotypes isolated from swine production in Argentina = Genes de virulencia y sensibilidad a antimicrobianos en serotipos de Salmonella enterica aislados de producción porcina en Argentina |
| title_full | Virulence genes and antimicrobial susceptibility in Salmonella enterica serotypes isolated from swine production in Argentina = Genes de virulencia y sensibilidad a antimicrobianos en serotipos de Salmonella enterica aislados de producción porcina en Argentina |
| title_fullStr | Virulence genes and antimicrobial susceptibility in Salmonella enterica serotypes isolated from swine production in Argentina = Genes de virulencia y sensibilidad a antimicrobianos en serotipos de Salmonella enterica aislados de producción porcina en Argentina |
| title_full_unstemmed | Virulence genes and antimicrobial susceptibility in Salmonella enterica serotypes isolated from swine production in Argentina = Genes de virulencia y sensibilidad a antimicrobianos en serotipos de Salmonella enterica aislados de producción porcina en Argentina |
| title_short | Virulence genes and antimicrobial susceptibility in Salmonella enterica serotypes isolated from swine production in Argentina = Genes de virulencia y sensibilidad a antimicrobianos en serotipos de Salmonella enterica aislados de producción porcina en Argentina |
| title_sort | virulence genes and antimicrobial susceptibility in salmonella enterica serotypes isolated from swine production in argentina genes de virulencia y sensibilidad a antimicrobianos en serotipos de salmonella enterica aislados de produccion porcina en argentina |
| topic | Salmonella Swine Antimicrobial Resistance Virulence Genes Cerdo Resistencia a los Antimicrobianos Virulencia |
| url | http://hdl.handle.net/20.500.12123/16101 https://www.sciencedirect.com/science/article/pii/S0325754120300973 https://doi.org/10.1016/j.ram.2020.10.001 |
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