Genome-Wide Analyses of Aspartic Proteases on Potato Genome (Solanum tuberosum): Generating New Tools to Improve the Resistance of Plants to Abiotic Stress

Aspartic proteases are proteolytic enzymes widely distributed in living organisms and viruses. Although they have been extensively studied in many plant species, they are poorly described in potatoes. The present study aimed to identify and characterize S. tuberosum aspartic proteases. Gene structur...

Full description

Bibliographic Details
Main Authors: Norero, Natalia Sigrid, Rey Burusco, María Florencia, D’Ippólito, Sebastián, Decima Oneto, Cecilia Andrea, Massa, Gabriela Alejandra, Castellote, Martín Alfredo, Feingold, Sergio Enrique, Guevara, María Gabriela
Format: info:ar-repo/semantics/artículo
Language:Inglés
Published: Multidisciplinary Digital Publishing Institute, MDPI 2023
Subjects:
Online Access:http://hdl.handle.net/20.500.12123/15532
https://www.mdpi.com/2223-7747/11/4/544
https://doi.org/10.3390/plants11040544
_version_ 1855037334718775296
author Norero, Natalia Sigrid
Rey Burusco, María Florencia
D’Ippólito, Sebastián
Decima Oneto, Cecilia Andrea
Massa, Gabriela Alejandra
Castellote, Martín Alfredo
Feingold, Sergio Enrique
Guevara, María Gabriela
author_browse Castellote, Martín Alfredo
Decima Oneto, Cecilia Andrea
D’Ippólito, Sebastián
Feingold, Sergio Enrique
Guevara, María Gabriela
Massa, Gabriela Alejandra
Norero, Natalia Sigrid
Rey Burusco, María Florencia
author_facet Norero, Natalia Sigrid
Rey Burusco, María Florencia
D’Ippólito, Sebastián
Decima Oneto, Cecilia Andrea
Massa, Gabriela Alejandra
Castellote, Martín Alfredo
Feingold, Sergio Enrique
Guevara, María Gabriela
author_sort Norero, Natalia Sigrid
collection INTA Digital
description Aspartic proteases are proteolytic enzymes widely distributed in living organisms and viruses. Although they have been extensively studied in many plant species, they are poorly described in potatoes. The present study aimed to identify and characterize S. tuberosum aspartic proteases. Gene structure, chromosome and protein domain organization, phylogeny, and subcellular predicted localization were analyzed and integrated with RNAseq data from different tissues, organs, and conditions focused on abiotic stress. Sixty-two aspartic protease genes were retrieved from the potato genome, distributed in 12 chromosomes. A high number of intronless genes and segmental and tandem duplications were detected. Phylogenetic analysis revealed eight StAP groups, named from StAPI to StAPVIII, that were differentiated into typical (StAPI), nucellin-like (StAPIIIa), and atypical aspartic proteases (StAPII, StAPIIIb to StAPVIII). RNAseq data analyses showed that gene expression was consistent with the presence of cis-acting regulatory elements on StAP promoter regions related to water deficit. The study presents the first identification and characterization of 62 aspartic protease genes and proteins on the potato genome and provides the baseline material for functional gene determinations and potato breeding programs, including gene editing mediated by CRISPR.
format info:ar-repo/semantics/artículo
id INTA15532
institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
language Inglés
publishDate 2023
publishDateRange 2023
publishDateSort 2023
publisher Multidisciplinary Digital Publishing Institute, MDPI
publisherStr Multidisciplinary Digital Publishing Institute, MDPI
record_format dspace
spelling INTA155322023-10-12T11:14:41Z Genome-Wide Analyses of Aspartic Proteases on Potato Genome (Solanum tuberosum): Generating New Tools to Improve the Resistance of Plants to Abiotic Stress Norero, Natalia Sigrid Rey Burusco, María Florencia D’Ippólito, Sebastián Decima Oneto, Cecilia Andrea Massa, Gabriela Alejandra Castellote, Martín Alfredo Feingold, Sergio Enrique Guevara, María Gabriela Papa Solanum tuberosum Genomas Proteasas Estrés Abiótico Potatoes Genomes Proteases Abiotic Stress Aspartic proteases are proteolytic enzymes widely distributed in living organisms and viruses. Although they have been extensively studied in many plant species, they are poorly described in potatoes. The present study aimed to identify and characterize S. tuberosum aspartic proteases. Gene structure, chromosome and protein domain organization, phylogeny, and subcellular predicted localization were analyzed and integrated with RNAseq data from different tissues, organs, and conditions focused on abiotic stress. Sixty-two aspartic protease genes were retrieved from the potato genome, distributed in 12 chromosomes. A high number of intronless genes and segmental and tandem duplications were detected. Phylogenetic analysis revealed eight StAP groups, named from StAPI to StAPVIII, that were differentiated into typical (StAPI), nucellin-like (StAPIIIa), and atypical aspartic proteases (StAPII, StAPIIIb to StAPVIII). RNAseq data analyses showed that gene expression was consistent with the presence of cis-acting regulatory elements on StAP promoter regions related to water deficit. The study presents the first identification and characterization of 62 aspartic protease genes and proteins on the potato genome and provides the baseline material for functional gene determinations and potato breeding programs, including gene editing mediated by CRISPR. EEA Balcarce Fil: Norero, Natalia Sigrid. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Fil: Rey Burusco, María Florencia. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina. Fil: D’Ippólito, Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata; Argentina. Instituto de Investigaciones Biológicas; Argentina. Fil: Décima Oneto, Cecilia Andrea. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Fil: Massa, Gabriela Alejandra. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Fil: Massa, Gabriela Alejandra. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina. Fil: Castellote, Martín Alfredo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Fil: Feingold, Sergio Enrique. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Fil: Guevara, María Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata; Argentina. Instituto de Investigaciones Biológicas; Argentina. 2023-10-12T11:10:51Z 2023-10-12T11:10:51Z 2022-02 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/15532 https://www.mdpi.com/2223-7747/11/4/544 2223-7747 https://doi.org/10.3390/plants11040544 eng info:eu-repograntAgreement/INTA/2019-PE-E6-I115-001, Edición génica, transgénesis y mutagénesis como generadores de nueva variabilidad en especies de interés agropecuario info:eu-repograntAgreement/INTA/2019-PD-E6-I116-001, Identificación y análisis funcional de genes o redes génicas de interés biotecnológico con fin agropecuario, forestal, agroalimentario y/o agroindustrial info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Multidisciplinary Digital Publishing Institute, MDPI Plants 11 (4) : 544 (February 2022)
spellingShingle Papa
Solanum tuberosum
Genomas
Proteasas
Estrés Abiótico
Potatoes
Genomes
Proteases
Abiotic Stress
Norero, Natalia Sigrid
Rey Burusco, María Florencia
D’Ippólito, Sebastián
Decima Oneto, Cecilia Andrea
Massa, Gabriela Alejandra
Castellote, Martín Alfredo
Feingold, Sergio Enrique
Guevara, María Gabriela
Genome-Wide Analyses of Aspartic Proteases on Potato Genome (Solanum tuberosum): Generating New Tools to Improve the Resistance of Plants to Abiotic Stress
title Genome-Wide Analyses of Aspartic Proteases on Potato Genome (Solanum tuberosum): Generating New Tools to Improve the Resistance of Plants to Abiotic Stress
title_full Genome-Wide Analyses of Aspartic Proteases on Potato Genome (Solanum tuberosum): Generating New Tools to Improve the Resistance of Plants to Abiotic Stress
title_fullStr Genome-Wide Analyses of Aspartic Proteases on Potato Genome (Solanum tuberosum): Generating New Tools to Improve the Resistance of Plants to Abiotic Stress
title_full_unstemmed Genome-Wide Analyses of Aspartic Proteases on Potato Genome (Solanum tuberosum): Generating New Tools to Improve the Resistance of Plants to Abiotic Stress
title_short Genome-Wide Analyses of Aspartic Proteases on Potato Genome (Solanum tuberosum): Generating New Tools to Improve the Resistance of Plants to Abiotic Stress
title_sort genome wide analyses of aspartic proteases on potato genome solanum tuberosum generating new tools to improve the resistance of plants to abiotic stress
topic Papa
Solanum tuberosum
Genomas
Proteasas
Estrés Abiótico
Potatoes
Genomes
Proteases
Abiotic Stress
url http://hdl.handle.net/20.500.12123/15532
https://www.mdpi.com/2223-7747/11/4/544
https://doi.org/10.3390/plants11040544
work_keys_str_mv AT noreronataliasigrid genomewideanalysesofasparticproteasesonpotatogenomesolanumtuberosumgeneratingnewtoolstoimprovetheresistanceofplantstoabioticstress
AT reyburuscomariaflorencia genomewideanalysesofasparticproteasesonpotatogenomesolanumtuberosumgeneratingnewtoolstoimprovetheresistanceofplantstoabioticstress
AT dippolitosebastian genomewideanalysesofasparticproteasesonpotatogenomesolanumtuberosumgeneratingnewtoolstoimprovetheresistanceofplantstoabioticstress
AT decimaonetoceciliaandrea genomewideanalysesofasparticproteasesonpotatogenomesolanumtuberosumgeneratingnewtoolstoimprovetheresistanceofplantstoabioticstress
AT massagabrielaalejandra genomewideanalysesofasparticproteasesonpotatogenomesolanumtuberosumgeneratingnewtoolstoimprovetheresistanceofplantstoabioticstress
AT castellotemartinalfredo genomewideanalysesofasparticproteasesonpotatogenomesolanumtuberosumgeneratingnewtoolstoimprovetheresistanceofplantstoabioticstress
AT feingoldsergioenrique genomewideanalysesofasparticproteasesonpotatogenomesolanumtuberosumgeneratingnewtoolstoimprovetheresistanceofplantstoabioticstress
AT guevaramariagabriela genomewideanalysesofasparticproteasesonpotatogenomesolanumtuberosumgeneratingnewtoolstoimprovetheresistanceofplantstoabioticstress