Blood-feeding adaptations and virome assessment of the poultry red mite Dermanyssus gallinae guided by RNA-seq

Dermanyssus gallinae is a blood-feeding mite that parasitises wild birds and farmed poultry. Its remarkably swift processing of blood, together with the capacity to blood-feed during most developmental stages, makes this mite a highly debilitating pest. To identify specific adaptations to digestion...

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Detalles Bibliográficos
Autores principales: Ribeiro, José M., Hartmann, David, Bartošová-Sojková, Pavla, Debat, Humberto Julio, Moos, Martin, Šimek, Petr, Fara, Jiří, Palus, Martin, Kučera, Matěj, Hajdušek, Ondřej
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: Springer Nature 2023
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/15196
https://www.nature.com/articles/s42003-023-04907-x
https://doi.org/10.1038/s42003-023-04907-x
Descripción
Sumario:Dermanyssus gallinae is a blood-feeding mite that parasitises wild birds and farmed poultry. Its remarkably swift processing of blood, together with the capacity to blood-feed during most developmental stages, makes this mite a highly debilitating pest. To identify specific adaptations to digestion of a haemoglobin-rich diet, we constructed and compared transcriptomes from starved and blood-fed stages of the parasite and identified midgut-enriched transcripts. We noted that midgut transcripts encoding cysteine proteases were upregulated with a blood meal. Mapping the full proteolytic apparatus, we noted a reduction in the suite of cysteine proteases, missing homologues for Cathepsin B and C.