Novel B2 mitogenomes from Continental southern Patagonia's Late Holocene : New insights into the peopling of the Southern Cone = Nuevos mitogenomas B2 del holoceno tardío del sur de la Patagonia Continental : Nuevos hallazgos sobre el poblamiento del Cono Sur
Objectives: The main aim of this study is to discuss the migratory processes and peopling dynamics that shaped the genetic variability of populations during the settlement of the Southern Cone, through the analysis of complete mitogenomes of individuals from southern Patagonia. Materials and Method...
| Autores principales: | , , , , , , , , , , |
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| Formato: | info:ar-repo/semantics/artículo |
| Lenguaje: | Inglés |
| Publicado: |
Wiley
2023
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12123/15129 https://onlinelibrary.wiley.com/doi/10.1002/ajpa.24822 https://doi.org/10.1002/ajpa.24822 |
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| author | Arencibia, Valeria Muñoz Hidalgo, Marianne Graziel Crespo, Cristian Russo, M. Gabriela Vera, Pablo Alfredo Lia, Veronica Viviana García Guraieb, Solana Goñi, Rafael A. Avena, Sergio Puebla, Andrea Fabiana Dejean, Cristina |
| author_browse | Arencibia, Valeria Avena, Sergio Crespo, Cristian Dejean, Cristina García Guraieb, Solana Goñi, Rafael A. Lia, Veronica Viviana Muñoz Hidalgo, Marianne Graziel Puebla, Andrea Fabiana Russo, M. Gabriela Vera, Pablo Alfredo |
| author_facet | Arencibia, Valeria Muñoz Hidalgo, Marianne Graziel Crespo, Cristian Russo, M. Gabriela Vera, Pablo Alfredo Lia, Veronica Viviana García Guraieb, Solana Goñi, Rafael A. Avena, Sergio Puebla, Andrea Fabiana Dejean, Cristina |
| author_sort | Arencibia, Valeria |
| collection | INTA Digital |
| description | Objectives: The main aim of this study is to discuss the migratory processes and peopling dynamics that shaped the genetic variability of populations during the settlement of the Southern Cone, through the analysis of complete mitogenomes of individuals from southern Patagonia.
Materials and Methods: Complete mitogenomes were sequenced through massively parallel sequencing from two late Holocene individuals (SAC 1-1-3 and SAC 1-1-4) buried in the same chenque at Salitroso Lake Basin (Santa Cruz province, Argentina). To evaluate matrilineal phylogenetic affinities with other haplotypes, maximum likelihood and Bayesian phylogenetic reconstructions were performed, as well as a haplotype median-joining network.
Results: The mitogenomes were assigned to haplogroups B2 and B2b, exhibiting an average depth of 54X and 89X (≥1X coverage of 98.6% and 100%), and a high number of nucleotide differences among them. The phylogenetic analyses showed a relatively close relationship between the haplotype found in SAC 1-1-4 and those retrieved from a Middle Holocene individual from Laguna Chica (Buenos Aires province), and from a group of individuals from the Peruvian coast. For the SAC 1-1-3, no clear affiliations to any other haplotype were established.
Discussion: The large divergence between the haplotypes presented in this study suggests either a highly variable founder gene pool, or a later enrichment by frequent biological contact with other populations. Our results underline the persistence of genetic signals related to the first waves of peopling in South America, suggesting that the regional settlement of the southern end of the continent has been much more complex than initially thought. |
| format | info:ar-repo/semantics/artículo |
| id | INTA15129 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | Wiley |
| publisherStr | Wiley |
| record_format | dspace |
| spelling | INTA151292023-09-07T10:20:31Z Novel B2 mitogenomes from Continental southern Patagonia's Late Holocene : New insights into the peopling of the Southern Cone = Nuevos mitogenomas B2 del holoceno tardío del sur de la Patagonia Continental : Nuevos hallazgos sobre el poblamiento del Cono Sur Arencibia, Valeria Muñoz Hidalgo, Marianne Graziel Crespo, Cristian Russo, M. Gabriela Vera, Pablo Alfredo Lia, Veronica Viviana García Guraieb, Solana Goñi, Rafael A. Avena, Sergio Puebla, Andrea Fabiana Dejean, Cristina Genetic Variation Holocene Variación Genética Holoceno Mitogenomes Mitogenomas Región Patagónica Objectives: The main aim of this study is to discuss the migratory processes and peopling dynamics that shaped the genetic variability of populations during the settlement of the Southern Cone, through the analysis of complete mitogenomes of individuals from southern Patagonia. Materials and Methods: Complete mitogenomes were sequenced through massively parallel sequencing from two late Holocene individuals (SAC 1-1-3 and SAC 1-1-4) buried in the same chenque at Salitroso Lake Basin (Santa Cruz province, Argentina). To evaluate matrilineal phylogenetic affinities with other haplotypes, maximum likelihood and Bayesian phylogenetic reconstructions were performed, as well as a haplotype median-joining network. Results: The mitogenomes were assigned to haplogroups B2 and B2b, exhibiting an average depth of 54X and 89X (≥1X coverage of 98.6% and 100%), and a high number of nucleotide differences among them. The phylogenetic analyses showed a relatively close relationship between the haplotype found in SAC 1-1-4 and those retrieved from a Middle Holocene individual from Laguna Chica (Buenos Aires province), and from a group of individuals from the Peruvian coast. For the SAC 1-1-3, no clear affiliations to any other haplotype were established. Discussion: The large divergence between the haplotypes presented in this study suggests either a highly variable founder gene pool, or a later enrichment by frequent biological contact with other populations. Our results underline the persistence of genetic signals related to the first waves of peopling in South America, suggesting that the regional settlement of the southern end of the continent has been much more complex than initially thought. Instituto de Biotecnología Fil: Arencibia, Valeria. Universidad Maimónides. Centro de Ciencias Naturales, Ambientales y Antropológicas (CCNAA); Argentina Fil: Arencibia, Valeria. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Muñoz Hidalgo, Marianne Graziel. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular (IABIMO); Argentina Fil: Muñoz Hidalgo, Marianne Graziel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Crespo, Cristian. Universidad Nacional de Tierra del Fuego. Instituto de Ciencias Polares, Ambiente y Recursos Naturales (ICPA); Argentina Fil: Russo, M. Gabriela. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución. Grupo de Investigación en Biología Evolutiva (GIBE); Argentina Fil: Vera, Pablo Alfredo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular (IABIMO); Argentina Fil: Vera, Pablo Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Lia, Veronica Viviana. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina Fil: Lia, Veronica Viviana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Lia, Veronica Viviana. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina Fil: García Guraieb, Solana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: García Guraieb, Solana. Instituto Nacional de Antropología y Pensamiento Latinoamericano (INAPL); Argentina Fil: García Guraieb, Solana. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Departamento de Ciencias Antropológicas; Argentina Fil: Goñi, Rafael A. Instituto Nacional de Antropología y Pensamiento Latinoamericano (INAPL); Argentina Fil: Goñi, Rafael A. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Departamento de Ciencias Antropológicas; Argentina Fil: Avena, Sergio. Universidad Maimónides. Centro de Ciencias Naturales, Ambientales y Antropológicas (CCNAA); Argentina Fil: Avena, Sergio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Avena, Sergio. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Departamento de Ciencias Antropológicas; Argentina Fil: Puebla, Andrea Fabiana. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular (IABIMO); Argentina Fil: Puebla, Andrea Fabiana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Dejean, Cristina. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular (IABIMO); Argentina Fil: Dejean, Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Dejean, Cristina. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Departamento de Ciencias Antropológicas; Argentina Fil: Dejean, Cristina. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto de Ciencias Antropológicas. Sección Antropología Biológica; Argentina 2023-09-07T10:10:25Z 2023-09-07T10:10:25Z 2023-08 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/15129 https://onlinelibrary.wiley.com/doi/10.1002/ajpa.24822 2692-7691 https://doi.org/10.1002/ajpa.24822 eng info:eu-repo/semantics/restrictedAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Wiley American Journal of Biological Anthropology (First published: 07 August 2023) |
| spellingShingle | Genetic Variation Holocene Variación Genética Holoceno Mitogenomes Mitogenomas Región Patagónica Arencibia, Valeria Muñoz Hidalgo, Marianne Graziel Crespo, Cristian Russo, M. Gabriela Vera, Pablo Alfredo Lia, Veronica Viviana García Guraieb, Solana Goñi, Rafael A. Avena, Sergio Puebla, Andrea Fabiana Dejean, Cristina Novel B2 mitogenomes from Continental southern Patagonia's Late Holocene : New insights into the peopling of the Southern Cone = Nuevos mitogenomas B2 del holoceno tardío del sur de la Patagonia Continental : Nuevos hallazgos sobre el poblamiento del Cono Sur |
| title | Novel B2 mitogenomes from Continental southern Patagonia's Late Holocene : New insights into the peopling of the Southern Cone = Nuevos mitogenomas B2 del holoceno tardío del sur de la Patagonia Continental : Nuevos hallazgos sobre el poblamiento del Cono Sur |
| title_full | Novel B2 mitogenomes from Continental southern Patagonia's Late Holocene : New insights into the peopling of the Southern Cone = Nuevos mitogenomas B2 del holoceno tardío del sur de la Patagonia Continental : Nuevos hallazgos sobre el poblamiento del Cono Sur |
| title_fullStr | Novel B2 mitogenomes from Continental southern Patagonia's Late Holocene : New insights into the peopling of the Southern Cone = Nuevos mitogenomas B2 del holoceno tardío del sur de la Patagonia Continental : Nuevos hallazgos sobre el poblamiento del Cono Sur |
| title_full_unstemmed | Novel B2 mitogenomes from Continental southern Patagonia's Late Holocene : New insights into the peopling of the Southern Cone = Nuevos mitogenomas B2 del holoceno tardío del sur de la Patagonia Continental : Nuevos hallazgos sobre el poblamiento del Cono Sur |
| title_short | Novel B2 mitogenomes from Continental southern Patagonia's Late Holocene : New insights into the peopling of the Southern Cone = Nuevos mitogenomas B2 del holoceno tardío del sur de la Patagonia Continental : Nuevos hallazgos sobre el poblamiento del Cono Sur |
| title_sort | novel b2 mitogenomes from continental southern patagonia s late holocene new insights into the peopling of the southern cone nuevos mitogenomas b2 del holoceno tardio del sur de la patagonia continental nuevos hallazgos sobre el poblamiento del cono sur |
| topic | Genetic Variation Holocene Variación Genética Holoceno Mitogenomes Mitogenomas Región Patagónica |
| url | http://hdl.handle.net/20.500.12123/15129 https://onlinelibrary.wiley.com/doi/10.1002/ajpa.24822 https://doi.org/10.1002/ajpa.24822 |
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