The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP
In plants, the establishment of broad and long-lasting immunity is based on programs that control systemic resistance and immunological memory or “priming”. Despite not showing activated defenses, a primed plant induces a more efficient response to recurrent infections. Priming might involve chromat...
| Main Authors: | , , , , , |
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| Format: | Artículo |
| Language: | Inglés |
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Frontiers Media
2023
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.12123/15128 https://www.frontiersin.org/articles/10.3389/fpls.2023.1133327/full https://doi.org/10.3389/fpls.2023.1133327 |
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| author | Miranda de la Torre, Julián O. Peppino Margutti, Micaela Y. Lescano Lopez, Carlos Ignacio Cambiagno, Damian Alejandro Alvarez, María E. Cecchini, Nicolás M. |
| author_browse | Alvarez, María E. Cambiagno, Damian Alejandro Cecchini, Nicolás M. Lescano Lopez, Carlos Ignacio Miranda de la Torre, Julián O. Peppino Margutti, Micaela Y. |
| author_facet | Miranda de la Torre, Julián O. Peppino Margutti, Micaela Y. Lescano Lopez, Carlos Ignacio Cambiagno, Damian Alejandro Alvarez, María E. Cecchini, Nicolás M. |
| author_sort | Miranda de la Torre, Julián O. |
| collection | INTA Digital |
| description | In plants, the establishment of broad and long-lasting immunity is based on programs that control systemic resistance and immunological memory or “priming”. Despite not showing activated defenses, a primed plant induces a more efficient response to recurrent infections. Priming might involve chromatin modifications that allow a faster/stronger activation of defense genes. The Arabidopsis chromatin regulator “Morpheus Molecule 1” (MOM1) has been recently suggested as a priming factor affecting the expression of immune receptor genes. Here, we show that mom1 mutants exacerbate the root growth inhibition response triggered by the key defense priming inducers azelaic acid (AZA), β-aminobutyric acid (BABA) and pipecolic acid (PIP). Conversely, mom1 mutants complemented with a minimal version of MOM1 (miniMOM1 plants) are insensitive. Moreover, miniMOM1 is unable to induce systemic resistance against Pseudomonas sp. in response to these inducers. Importantly, AZA, BABA and PIP treatments reduce the MOM1 expression, but not miniMOM1 transcript levels, in systemic tissues. Consistently, several MOM1-regulated immune receptor genes are upregulated during the activation of systemic resistance in WT plants, while this effect is not observed in miniMOM1. Taken together, our results position MOM1 as a chromatin factor that negatively regulates the defense priming induced by AZA, BABA and PIP. |
| format | Artículo |
| id | INTA15128 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | Frontiers Media |
| publisherStr | Frontiers Media |
| record_format | dspace |
| spelling | INTA151282023-09-07T10:05:47Z The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP Miranda de la Torre, Julián O. Peppino Margutti, Micaela Y. Lescano Lopez, Carlos Ignacio Cambiagno, Damian Alejandro Alvarez, María E. Cecchini, Nicolás M. Arabidopsis Chromatin Cromatina Azelaic Acid Pipecolic Acid B-Aminobutyric Acid Plant Defense Priming MOM1 In plants, the establishment of broad and long-lasting immunity is based on programs that control systemic resistance and immunological memory or “priming”. Despite not showing activated defenses, a primed plant induces a more efficient response to recurrent infections. Priming might involve chromatin modifications that allow a faster/stronger activation of defense genes. The Arabidopsis chromatin regulator “Morpheus Molecule 1” (MOM1) has been recently suggested as a priming factor affecting the expression of immune receptor genes. Here, we show that mom1 mutants exacerbate the root growth inhibition response triggered by the key defense priming inducers azelaic acid (AZA), β-aminobutyric acid (BABA) and pipecolic acid (PIP). Conversely, mom1 mutants complemented with a minimal version of MOM1 (miniMOM1 plants) are insensitive. Moreover, miniMOM1 is unable to induce systemic resistance against Pseudomonas sp. in response to these inducers. Importantly, AZA, BABA and PIP treatments reduce the MOM1 expression, but not miniMOM1 transcript levels, in systemic tissues. Consistently, several MOM1-regulated immune receptor genes are upregulated during the activation of systemic resistance in WT plants, while this effect is not observed in miniMOM1. Taken together, our results position MOM1 as a chromatin factor that negatively regulates the defense priming induced by AZA, BABA and PIP. Instituto de Fisiología y Recursos Genéticos Vegetales Fil: Miranda de la Torre, Julián O. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina Fil: Miranda de la Torre, Julián O. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; Argentina Fil: Peppino Margutti, Micaela Y. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina Fil: Peppino Margutti, Micaela Y. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; Argentina Fil: Lescano Lopez, Carlos Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Estudios Agropecuarios (UDEA) ; Argentina Fil: Lescano Lopez, Carlos Ignacio. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Fisiología y Recursos Genéticos Vegetales; Argentina Fil: Lescano Lopez, Carlos Ignacio. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina Fil: Lescano Lopez, Carlos Ignacio.Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; Argentina Fil: Cambiagno, Damian Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Estudios Agropecuarios (UDEA) ; Argentina Fil: Cambiagno, Damian Alejandro. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Fisiología y Recursos Genéticos Vegetales; Argentina Fil: Cambiagno, Damian Alejandro.Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina Fil: Alvarez, María E. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; Argentina Fil: Cecchini, Nicolás M. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; Argentina 2023-09-07T09:59:05Z 2023-09-07T09:59:05Z 2023-05-09 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/15128 https://www.frontiersin.org/articles/10.3389/fpls.2023.1133327/full 1664-462X (online) https://doi.org/10.3389/fpls.2023.1133327 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Frontiers Media Frontiers in Plant Science 14 : 1133327 (09 May 2023) |
| spellingShingle | Arabidopsis Chromatin Cromatina Azelaic Acid Pipecolic Acid B-Aminobutyric Acid Plant Defense Priming MOM1 Miranda de la Torre, Julián O. Peppino Margutti, Micaela Y. Lescano Lopez, Carlos Ignacio Cambiagno, Damian Alejandro Alvarez, María E. Cecchini, Nicolás M. The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP |
| title | The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP |
| title_full | The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP |
| title_fullStr | The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP |
| title_full_unstemmed | The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP |
| title_short | The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP |
| title_sort | arabidopsis chromatin regulator mom1 is a negative component of the defense priming induced by aza baba and pip |
| topic | Arabidopsis Chromatin Cromatina Azelaic Acid Pipecolic Acid B-Aminobutyric Acid Plant Defense Priming MOM1 |
| url | http://hdl.handle.net/20.500.12123/15128 https://www.frontiersin.org/articles/10.3389/fpls.2023.1133327/full https://doi.org/10.3389/fpls.2023.1133327 |
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