Caprine brucellosis : a historically neglected disease with significant impact on public health
Caprine brucellosis is a chronic infectious disease caused by the gram-negative cocci-bacillus Brucella melitensis. Middle- to late-term abortion, stillbirths, and the delivery of weak offspring are the characteristic clinical signs of the disease that is associated with an extensive negative impact...
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| Format: | Artículo |
| Language: | Inglés |
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2017
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| Online Access: | http://hdl.handle.net/20.500.12123/1486 http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005692 https://doi.org/10.1371/journal.pntd.0005692 |
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| author | Rossetti, Carlos Alberto Arenas-Gamboa, Angela M. Maurizio, Estefania |
| author_browse | Arenas-Gamboa, Angela M. Maurizio, Estefania Rossetti, Carlos Alberto |
| author_facet | Rossetti, Carlos Alberto Arenas-Gamboa, Angela M. Maurizio, Estefania |
| author_sort | Rossetti, Carlos Alberto |
| collection | INTA Digital |
| description | Caprine brucellosis is a chronic infectious disease caused by the gram-negative cocci-bacillus Brucella melitensis. Middle- to late-term abortion, stillbirths, and the delivery of weak offspring are the characteristic clinical signs of the disease that is associated with an extensive negative impact in a flock's productivity. B. melitensis is also the most virulent Brucella species for humans, responsible for a severely debilitating and disabling illness that results in high morbidity with intermittent fever, chills, sweats, weakness, myalgia, abortion, osteoarticular
complications, endocarditis, depression, anorexia, and low mortality. Historical observations indicate that goats have been the hosts of B. melitensis for centuries; but around 1905, the Greek physician Themistokles Zammit was able to build the epidemiological link between ªMalta feverº and the consumption of goat milk. While the disease has been successfully managed in most industrialized countries, it remains a significant burden on goat and human health in the Mediterranean region, the Middle East, Central and Southeast Asia (including India and China), sub-Saharan Africa, and certain areas in Latin America, where
approximately 3.5 billion people live at risk. In this review, we describe a historical evolution of the disease, highlight the current worldwide distribution, and estimate (by simple formula) the approximate costs of brucellosis outbreaks to meat- and milk-producing farms and the economic losses associated with the disease in humans. Successful control leading to eradication of caprine brucellosis in the developing world will require a coordinated Global One Health approach involving active involvement of human and animal health efforts to enhance public health and improve livestock productivity. |
| format | Artículo |
| id | INTA1486 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| record_format | dspace |
| spelling | INTA14862018-01-09T13:05:23Z Caprine brucellosis : a historically neglected disease with significant impact on public health Rossetti, Carlos Alberto Arenas-Gamboa, Angela M. Maurizio, Estefania Brucelosis Enfermedades de los Animales Caprinos Salud Pública Animal Diseases Brucellosis Goats Public Health Caprine brucellosis is a chronic infectious disease caused by the gram-negative cocci-bacillus Brucella melitensis. Middle- to late-term abortion, stillbirths, and the delivery of weak offspring are the characteristic clinical signs of the disease that is associated with an extensive negative impact in a flock's productivity. B. melitensis is also the most virulent Brucella species for humans, responsible for a severely debilitating and disabling illness that results in high morbidity with intermittent fever, chills, sweats, weakness, myalgia, abortion, osteoarticular complications, endocarditis, depression, anorexia, and low mortality. Historical observations indicate that goats have been the hosts of B. melitensis for centuries; but around 1905, the Greek physician Themistokles Zammit was able to build the epidemiological link between ªMalta feverº and the consumption of goat milk. While the disease has been successfully managed in most industrialized countries, it remains a significant burden on goat and human health in the Mediterranean region, the Middle East, Central and Southeast Asia (including India and China), sub-Saharan Africa, and certain areas in Latin America, where approximately 3.5 billion people live at risk. In this review, we describe a historical evolution of the disease, highlight the current worldwide distribution, and estimate (by simple formula) the approximate costs of brucellosis outbreaks to meat- and milk-producing farms and the economic losses associated with the disease in humans. Successful control leading to eradication of caprine brucellosis in the developing world will require a coordinated Global One Health approach involving active involvement of human and animal health efforts to enhance public health and improve livestock productivity. Inst. de Patobiología Fil: Rossetti, Carlos Alberto. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina Fil: Arenas-Gamboa, Angela M. Texas A&M University. College of Veterinary Medicine & Biomedical Sciences. Department of Veterinary Pathobiology; Estados Unidos Fil: Maurizio, Estefania. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina 2017-10-13T13:52:48Z 2017-10-13T13:52:48Z 2017-08 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion info:ar-repo/semantics/artículo http://hdl.handle.net/20.500.12123/1486 http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005692 1935-2727 (Print) 1935-2735 (Online) https://doi.org/10.1371/journal.pntd.0005692 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf PLOS neglected tropical diseases 11 (8) : e0005692. (August 2017) |
| spellingShingle | Brucelosis Enfermedades de los Animales Caprinos Salud Pública Animal Diseases Brucellosis Goats Public Health Rossetti, Carlos Alberto Arenas-Gamboa, Angela M. Maurizio, Estefania Caprine brucellosis : a historically neglected disease with significant impact on public health |
| title | Caprine brucellosis : a historically neglected disease with significant impact on public health |
| title_full | Caprine brucellosis : a historically neglected disease with significant impact on public health |
| title_fullStr | Caprine brucellosis : a historically neglected disease with significant impact on public health |
| title_full_unstemmed | Caprine brucellosis : a historically neglected disease with significant impact on public health |
| title_short | Caprine brucellosis : a historically neglected disease with significant impact on public health |
| title_sort | caprine brucellosis a historically neglected disease with significant impact on public health |
| topic | Brucelosis Enfermedades de los Animales Caprinos Salud Pública Animal Diseases Brucellosis Goats Public Health |
| url | http://hdl.handle.net/20.500.12123/1486 http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005692 https://doi.org/10.1371/journal.pntd.0005692 |
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