Babesiosis prevalence in malaria-endemic regions of Colombia
Background & objectives: The presence of Babesia spp in humans, bovine cattle and ticks (the transmitting vector) has not been well characterized in Colombia. Babesia infection in humans can be overlooked due to similarity of the disease symptoms with malaria specially in the regions where malaria i...
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| Formato: | Artículo |
| Lenguaje: | Inglés |
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Wolters Kluwer
2023
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| Acceso en línea: | http://hdl.handle.net/20.500.12123/14797 https://bibliotecadigital.udea.edu.co/handle/10495/21556 https://doi.org/10.4103/0972-9062.249480 |
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| author | González Obando, Juliana Echaide, Ignacio Eduardo Pabón Vidal, Adriana Lucía Piñeros Jiménez, Juan Gabriel Blair Trujillo, Silvia Tobón Castaño, Alberto |
| author_browse | Blair Trujillo, Silvia Echaide, Ignacio Eduardo González Obando, Juliana Pabón Vidal, Adriana Lucía Piñeros Jiménez, Juan Gabriel Tobón Castaño, Alberto |
| author_facet | González Obando, Juliana Echaide, Ignacio Eduardo Pabón Vidal, Adriana Lucía Piñeros Jiménez, Juan Gabriel Blair Trujillo, Silvia Tobón Castaño, Alberto |
| author_sort | González Obando, Juliana |
| collection | INTA Digital |
| description | Background & objectives: The presence of Babesia spp in humans, bovine cattle and ticks (the transmitting vector) has not been well characterized in Colombia. Babesia infection in humans can be overlooked due to similarity of the disease symptoms with malaria specially in the regions where malaria is endemic. The aim of the present work was to study the frequency of Babesia infection in humans, bovines and ticks in a malaria endemic region of Colombia, and explore the possible relationship of infection with host and the environmental factors. Methods: A cross-sectional study was carried out between August 2014 and March 2015 to determine the frequency of B. bovis and B. bigemina infection in a sample of 300 humans involved in cattle raising, in 202 bovines; and in 515 ticks obtained from these subjects, using molecular (PCR), microscopic and serological methods. In addition, the demographic, ecological and zootechnical factors associated with the presence of Babesia, were explored. Results: In the bovine population, the prevalence of infection was 14.4% (29/202); the highest risk of infection was found in cattle under nine months of age (OR = 23.9, CI 8.10–94.30, p = 0.0). In humans, a prevalence of 2% (6/300) was found; four of these six cases were positive for B. bovis. Self-report of fever in the last seven days in the positive cases was found to be associated with Babesia infection (Incidence rate ratio = 9.08; CI 1.34–61.10, p = 0.02). The frequency of B. bigemina infection in the collected ticks was 18.5% (30/162). Interpretation & conclusion: The study established the presence of Babesia spp in humans, bovines and ticks. The most prevalent species responsible for babesiosis in humans and bovines was B. bovis, while B. bigemina was the species most frequently found in the tick population. The results contribute to the knowledge of the epidemiology of babesiosis in the country and can provide guidelines for the epidemiological surveillance of this non-malarial febrile illness in humans as well as cattle. |
| format | Artículo |
| id | INTA14797 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | Wolters Kluwer |
| publisherStr | Wolters Kluwer |
| record_format | dspace |
| spelling | INTA147972023-07-21T13:23:46Z Babesiosis prevalence in malaria-endemic regions of Colombia González Obando, Juliana Echaide, Ignacio Eduardo Pabón Vidal, Adriana Lucía Piñeros Jiménez, Juan Gabriel Blair Trujillo, Silvia Tobón Castaño, Alberto Babesiosis Cattle Tick-borne Diseases Malaria Babesia bigemina Ganado Bovino Enfermedades Transmitidas por Garrapatas Colombia Background & objectives: The presence of Babesia spp in humans, bovine cattle and ticks (the transmitting vector) has not been well characterized in Colombia. Babesia infection in humans can be overlooked due to similarity of the disease symptoms with malaria specially in the regions where malaria is endemic. The aim of the present work was to study the frequency of Babesia infection in humans, bovines and ticks in a malaria endemic region of Colombia, and explore the possible relationship of infection with host and the environmental factors. Methods: A cross-sectional study was carried out between August 2014 and March 2015 to determine the frequency of B. bovis and B. bigemina infection in a sample of 300 humans involved in cattle raising, in 202 bovines; and in 515 ticks obtained from these subjects, using molecular (PCR), microscopic and serological methods. In addition, the demographic, ecological and zootechnical factors associated with the presence of Babesia, were explored. Results: In the bovine population, the prevalence of infection was 14.4% (29/202); the highest risk of infection was found in cattle under nine months of age (OR = 23.9, CI 8.10–94.30, p = 0.0). In humans, a prevalence of 2% (6/300) was found; four of these six cases were positive for B. bovis. Self-report of fever in the last seven days in the positive cases was found to be associated with Babesia infection (Incidence rate ratio = 9.08; CI 1.34–61.10, p = 0.02). The frequency of B. bigemina infection in the collected ticks was 18.5% (30/162). Interpretation & conclusion: The study established the presence of Babesia spp in humans, bovines and ticks. The most prevalent species responsible for babesiosis in humans and bovines was B. bovis, while B. bigemina was the species most frequently found in the tick population. The results contribute to the knowledge of the epidemiology of babesiosis in the country and can provide guidelines for the epidemiological surveillance of this non-malarial febrile illness in humans as well as cattle. EEA Rafaela Fil: González Obando, Juliana. Universidad de Antioquia. Facultad de Medicina. Malaria Group; Colombia Fil: Echaide, Eduardo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina Fil: Pabón Vidal, Adriana Lucía. Universidad de Antioquia. Facultad de Medicina. Malaria Group; Colombia Fil: Piñeros Jiménez, Juan Gabriel. Universidad de Antioquia. Facultad de Medicina. Malaria Group; Colombia Fil: Blair Trujillo, Silvia. Universidad de Antioquia. Facultad de Medicina. Malaria Group; Colombia Fil: Tobón Castaño, Alberto. Universidad de Antioquia. Facultad de Medicina. Malaria Group; Colombia 2023-07-21T13:21:19Z 2023-07-21T13:21:19Z 2018-07 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/14797 https://bibliotecadigital.udea.edu.co/handle/10495/21556 0972-9062 https://doi.org/10.4103/0972-9062.249480 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Colombia .......... (nation) (World, South America) 1000050 Wolters Kluwer Journal of Vector Borne Diseases 55 (3) : 222-229. (Jul.-Sep. 2018) |
| spellingShingle | Babesiosis Cattle Tick-borne Diseases Malaria Babesia bigemina Ganado Bovino Enfermedades Transmitidas por Garrapatas Colombia González Obando, Juliana Echaide, Ignacio Eduardo Pabón Vidal, Adriana Lucía Piñeros Jiménez, Juan Gabriel Blair Trujillo, Silvia Tobón Castaño, Alberto Babesiosis prevalence in malaria-endemic regions of Colombia |
| title | Babesiosis prevalence in malaria-endemic regions of Colombia |
| title_full | Babesiosis prevalence in malaria-endemic regions of Colombia |
| title_fullStr | Babesiosis prevalence in malaria-endemic regions of Colombia |
| title_full_unstemmed | Babesiosis prevalence in malaria-endemic regions of Colombia |
| title_short | Babesiosis prevalence in malaria-endemic regions of Colombia |
| title_sort | babesiosis prevalence in malaria endemic regions of colombia |
| topic | Babesiosis Cattle Tick-borne Diseases Malaria Babesia bigemina Ganado Bovino Enfermedades Transmitidas por Garrapatas Colombia |
| url | http://hdl.handle.net/20.500.12123/14797 https://bibliotecadigital.udea.edu.co/handle/10495/21556 https://doi.org/10.4103/0972-9062.249480 |
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