Realistic scenarios of pesticide exposure alters multiple biomarkers in BOANA PULCHELLA (ANURA) Adult Frogs
Imazethapyr, a post-emergent herbicide used in worldwide soybean and corn crops, induces genetic and biochemical alterations in aquatic vertebrates. This study examined the relationship between biomarkers at different organization levels and imazethapyr real-life route exposure in Boana pulchella ad...
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| Format: | Artículo |
| Language: | Inglés |
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Springer
2023
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| Online Access: | http://hdl.handle.net/20.500.12123/14340 https://link.springer.com/article/10.1007/s10646-023-02639-6 https://doi.org/10.1007/s10646-023-02639-6 |
| _version_ | 1855485343889883136 |
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| author | Pérez-Iglesias, Juan Manuel Natale, Guillermo S. Brodeur, Celine Marie Larramendy, Marcelo L. |
| author_browse | Brodeur, Celine Marie Larramendy, Marcelo L. Natale, Guillermo S. Pérez-Iglesias, Juan Manuel |
| author_facet | Pérez-Iglesias, Juan Manuel Natale, Guillermo S. Brodeur, Celine Marie Larramendy, Marcelo L. |
| author_sort | Pérez-Iglesias, Juan Manuel |
| collection | INTA Digital |
| description | Imazethapyr, a post-emergent herbicide used in worldwide soybean and corn crops, induces genetic and biochemical alterations in aquatic vertebrates. This study examined the relationship between biomarkers at different organization levels and imazethapyr real-life route exposure in Boana pulchella adults. Frogs were exposed to imazethapyr-based formulation Pivot® H (10.59%) at concentrations representing possible acute routes: field runoff (S1:10 mg.L−1), exposure after direct foliar application (S2:100 mg.L−1) and during direct foliar application (S3:1000 mg.L−1). Post-exposure, endpoints levels were evaluated: organism alterations, biochemical activities and cytogenetic assays. Forty-eight hours post-exposure, antioxidant enzymes decrease, micronuclei induction and DNA damage were observed in all scenarios, while cholinesterase activity increase and body condition reduction were observed in frog-exposed to S3. Ninety-six hours postexposure, frogs showed glutathione-S-transferase inhibition in S1, micronuclei induction in S2 and S3, and DNA-damage increase in S3. Herbicides routes of exposures in real-life could indicate that authorized applications have a risk to
amphibian populations. |
| format | Artículo |
| id | INTA14340 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | Springer |
| publisherStr | Springer |
| record_format | dspace |
| spelling | INTA143402023-03-28T18:09:06Z Realistic scenarios of pesticide exposure alters multiple biomarkers in BOANA PULCHELLA (ANURA) Adult Frogs Pérez-Iglesias, Juan Manuel Natale, Guillermo S. Brodeur, Celine Marie Larramendy, Marcelo L. Rana Fitotoxicidad Phytotoxicity Frogs Pesticides Plaguicidas Biomarkers Integrative Responses Dermal Exposure Imazethapyr Phisiological Stress Respuestas Integradoras de Biomarcadores Exposición Dérmica Estrés Fisiológico Boana pulchella Imazethapyr, a post-emergent herbicide used in worldwide soybean and corn crops, induces genetic and biochemical alterations in aquatic vertebrates. This study examined the relationship between biomarkers at different organization levels and imazethapyr real-life route exposure in Boana pulchella adults. Frogs were exposed to imazethapyr-based formulation Pivot® H (10.59%) at concentrations representing possible acute routes: field runoff (S1:10 mg.L−1), exposure after direct foliar application (S2:100 mg.L−1) and during direct foliar application (S3:1000 mg.L−1). Post-exposure, endpoints levels were evaluated: organism alterations, biochemical activities and cytogenetic assays. Forty-eight hours post-exposure, antioxidant enzymes decrease, micronuclei induction and DNA damage were observed in all scenarios, while cholinesterase activity increase and body condition reduction were observed in frog-exposed to S3. Ninety-six hours postexposure, frogs showed glutathione-S-transferase inhibition in S1, micronuclei induction in S2 and S3, and DNA-damage increase in S3. Herbicides routes of exposures in real-life could indicate that authorized applications have a risk to amphibian populations. Instituto de Recursos Biológicos Fil: Pérez Iglesias, J.M. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigaciones del Medio Ambiente (CIM); Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Cátedra de Citología; Argentina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina. Fil: Natale, G.S. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigaciones del Medio Ambiente (CIM); Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Brodeur, Celine Marie Julie. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Recursos Biológicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Larramendy, Marcelo L. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Cátedra de Citología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina 2023-03-28T17:29:38Z 2023-03-28T17:29:38Z 2023-03-01 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/14340 https://link.springer.com/article/10.1007/s10646-023-02639-6 1573-3017 0963-9292 https://doi.org/10.1007/s10646-023-02639-6 eng info:eu-repograntAgreement/INTA/2019-PE-E2-I054-001/2019-PE-E2-I054-001/AR./Gestión sostenible de fitosanitarios info:eu-repo/semantics/restrictedAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Springer Ecotoxicology 32 (2) : 1-12 (Published: 16 March 2023) |
| spellingShingle | Rana Fitotoxicidad Phytotoxicity Frogs Pesticides Plaguicidas Biomarkers Integrative Responses Dermal Exposure Imazethapyr Phisiological Stress Respuestas Integradoras de Biomarcadores Exposición Dérmica Estrés Fisiológico Boana pulchella Pérez-Iglesias, Juan Manuel Natale, Guillermo S. Brodeur, Celine Marie Larramendy, Marcelo L. Realistic scenarios of pesticide exposure alters multiple biomarkers in BOANA PULCHELLA (ANURA) Adult Frogs |
| title | Realistic scenarios of pesticide exposure alters multiple biomarkers in BOANA PULCHELLA (ANURA) Adult Frogs |
| title_full | Realistic scenarios of pesticide exposure alters multiple biomarkers in BOANA PULCHELLA (ANURA) Adult Frogs |
| title_fullStr | Realistic scenarios of pesticide exposure alters multiple biomarkers in BOANA PULCHELLA (ANURA) Adult Frogs |
| title_full_unstemmed | Realistic scenarios of pesticide exposure alters multiple biomarkers in BOANA PULCHELLA (ANURA) Adult Frogs |
| title_short | Realistic scenarios of pesticide exposure alters multiple biomarkers in BOANA PULCHELLA (ANURA) Adult Frogs |
| title_sort | realistic scenarios of pesticide exposure alters multiple biomarkers in boana pulchella anura adult frogs |
| topic | Rana Fitotoxicidad Phytotoxicity Frogs Pesticides Plaguicidas Biomarkers Integrative Responses Dermal Exposure Imazethapyr Phisiological Stress Respuestas Integradoras de Biomarcadores Exposición Dérmica Estrés Fisiológico Boana pulchella |
| url | http://hdl.handle.net/20.500.12123/14340 https://link.springer.com/article/10.1007/s10646-023-02639-6 https://doi.org/10.1007/s10646-023-02639-6 |
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