Combined use of monensin and virginiamycin to improve rumen and liver health and performance of feedlot-finished steers

Monensin and virginiamycin are included in beef cattle finishing diets as prophylaxis to minimize the incidence of ruminal acidosis and liver abscesses. Due to different and probably complementary modes of action, this study aimed to determine the effects of a combination of monensin and virginiamyc...

Descripción completa

Detalles Bibliográficos
Autores principales: Ceconi, Irene, Viano, Sergio, Mendez, Daniel Gustavo, Gonzalez, Lucas, Davies, Patricio, Elizalde, Juan Carlos, Bressan, Elbio, Grandini, Danilo, Nagaraja, T.G., Tedeschi, Luis O.
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: American Society of Animal Science 2023
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/14273
https://academic.oup.com/tas/article/6/4/txac154/6862071
https://doi.org/10.1093/tas/txac154
_version_ 1855037088029736960
author Ceconi, Irene
Viano, Sergio
Mendez, Daniel Gustavo
Gonzalez, Lucas
Davies, Patricio
Elizalde, Juan Carlos
Bressan, Elbio
Grandini, Danilo
Nagaraja, T.G.
Tedeschi, Luis O.
author_browse Bressan, Elbio
Ceconi, Irene
Davies, Patricio
Elizalde, Juan Carlos
Gonzalez, Lucas
Grandini, Danilo
Mendez, Daniel Gustavo
Nagaraja, T.G.
Tedeschi, Luis O.
Viano, Sergio
author_facet Ceconi, Irene
Viano, Sergio
Mendez, Daniel Gustavo
Gonzalez, Lucas
Davies, Patricio
Elizalde, Juan Carlos
Bressan, Elbio
Grandini, Danilo
Nagaraja, T.G.
Tedeschi, Luis O.
author_sort Ceconi, Irene
collection INTA Digital
description Monensin and virginiamycin are included in beef cattle finishing diets as prophylaxis to minimize the incidence of ruminal acidosis and liver abscesses. Due to different and probably complementary modes of action, this study aimed to determine the effects of a combination of monensin and virginiamycin, both included in the diet at recommended doses, on ruminal health, the occurrence of liver abscesses, and growth performance of feedlot-finished cattle. One hundred and forty-four steers (6 animals/pen) were fed 1 of 3 corn-based finishing diets containing 30 mg of monensin (MN), 25 mg of virginiamycin (VM), or 30 and 25 mg of monensin and virginiamycin (MN + VM), respectively, per kilogram of dry matter. Ruminal pH probes were inserted into two animals per pen and set to record pH every 10 min. On d 100, animals were slaughtered, and rumens and livers were recovered, on which occurrence and degree of ruminal damage, prevalence and number of liver abscesses, and liver scores (A−: livers with no more than two small abscesses; A+: livers with at least one large abscess or more than four medium abscesses; A: any other abscessed liver) were determined. Simultaneous inclusion of monensin and virginiamycin resulted in a 4.3% decrease (P < 0.04) in dry matter intake (DMI; 8.8, 9.2, and 9.2 ± 0.19 kg/d for MN + VM, MN, and VM-fed animals, respectively) and similar (P > 0.13) average daily body weight gain (ADG; 1.49 ± 0.021 kg/d) and hot carcass weight (HCW; 269 ± 1.7 kg), compared with feeding diets containing one additive or the other. Therefore, in terms of ADG, a 9.4% improvement (P < 0.01) in feed efficiency was observed in MN + VM-fed animals. Backfat thickness (5.6 ± 0.08 mm) and ribeye area (69.9 ± 0.53 cm2) remained unaffected (P ≥ 0.74), as well as the minimum (4.98 ± 0.047), mean (6.11 ± 0.037), and maximum ruminal pH (7.23 ± 0.033) values and the time (125 ± 22.3 min/d), area (57.67 ± 12.383 pH × h), and episodes (22 ± 3.8 bouts) of pH below 5.6 (P ≥ 0.12). Overall, prevalence (24 ± 3.4%) and the number of liver abscesses (1.6 ± 0.14 abscesses/abscessed liver), liver scores (20 ± 3.1% of A− and 4 ± 1.8% of A livers), and prevalence (67 ± 3.5%) and degree of damage to the ruminal epithelium (2.5 ± 0.22% affected surface) were similar (P ≥ 0.18) across treatments; however, the occurrence of ruminal lesions tended (P ≤ 0.07) to be associated with that of liver abscesses and reduced ADG when feeding monensin alone.
format info:ar-repo/semantics/artículo
id INTA14273
institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
language Inglés
publishDate 2023
publishDateRange 2023
publishDateSort 2023
publisher American Society of Animal Science
publisherStr American Society of Animal Science
record_format dspace
spelling INTA142732023-03-22T12:18:42Z Combined use of monensin and virginiamycin to improve rumen and liver health and performance of feedlot-finished steers Ceconi, Irene Viano, Sergio Mendez, Daniel Gustavo Gonzalez, Lucas Davies, Patricio Elizalde, Juan Carlos Bressan, Elbio Grandini, Danilo Nagaraja, T.G. Tedeschi, Luis O. Buey Ganado Bovino Monensina Virginiamicina Feedlot Sanidad Animal Bullocks Cattle Monensin Virginiamycin Feedlots Animal Health Steers Novillo Monensin and virginiamycin are included in beef cattle finishing diets as prophylaxis to minimize the incidence of ruminal acidosis and liver abscesses. Due to different and probably complementary modes of action, this study aimed to determine the effects of a combination of monensin and virginiamycin, both included in the diet at recommended doses, on ruminal health, the occurrence of liver abscesses, and growth performance of feedlot-finished cattle. One hundred and forty-four steers (6 animals/pen) were fed 1 of 3 corn-based finishing diets containing 30 mg of monensin (MN), 25 mg of virginiamycin (VM), or 30 and 25 mg of monensin and virginiamycin (MN + VM), respectively, per kilogram of dry matter. Ruminal pH probes were inserted into two animals per pen and set to record pH every 10 min. On d 100, animals were slaughtered, and rumens and livers were recovered, on which occurrence and degree of ruminal damage, prevalence and number of liver abscesses, and liver scores (A−: livers with no more than two small abscesses; A+: livers with at least one large abscess or more than four medium abscesses; A: any other abscessed liver) were determined. Simultaneous inclusion of monensin and virginiamycin resulted in a 4.3% decrease (P < 0.04) in dry matter intake (DMI; 8.8, 9.2, and 9.2 ± 0.19 kg/d for MN + VM, MN, and VM-fed animals, respectively) and similar (P > 0.13) average daily body weight gain (ADG; 1.49 ± 0.021 kg/d) and hot carcass weight (HCW; 269 ± 1.7 kg), compared with feeding diets containing one additive or the other. Therefore, in terms of ADG, a 9.4% improvement (P < 0.01) in feed efficiency was observed in MN + VM-fed animals. Backfat thickness (5.6 ± 0.08 mm) and ribeye area (69.9 ± 0.53 cm2) remained unaffected (P ≥ 0.74), as well as the minimum (4.98 ± 0.047), mean (6.11 ± 0.037), and maximum ruminal pH (7.23 ± 0.033) values and the time (125 ± 22.3 min/d), area (57.67 ± 12.383 pH × h), and episodes (22 ± 3.8 bouts) of pH below 5.6 (P ≥ 0.12). Overall, prevalence (24 ± 3.4%) and the number of liver abscesses (1.6 ± 0.14 abscesses/abscessed liver), liver scores (20 ± 3.1% of A− and 4 ± 1.8% of A livers), and prevalence (67 ± 3.5%) and degree of damage to the ruminal epithelium (2.5 ± 0.22% affected surface) were similar (P ≥ 0.18) across treatments; however, the occurrence of ruminal lesions tended (P ≤ 0.07) to be associated with that of liver abscesses and reduced ADG when feeding monensin alone. EEA General Villegas Fil: Ceconi, Irene. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria General Villegas; Argentina Fil: Viano, Sergio. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria General Villegas; Argentina Fil: Méndez, Daniel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria General Villegas; Argentina Fil: González, Lucas. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria General Villegas; Argentina Fil: Davies, Patricio. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria General Villegas; Argentina Fil: Elizalde, J. C. Actividad privada; Argentina Fil: Bressan, Elbio. Phibro Animal Health; Argentina Fil: Grandini, Danilo. Phibro Animal Health; Brasil Fil: Nagaraja, T.G. Kansas State University. Department of Diagnostic Medicine/Pathobiology; Estados Unidos Fil: Tedeschi, Luis O. Texas A&M University. Department of Animal Science; Estados Unidos 2023-03-20T11:10:36Z 2023-03-20T11:10:36Z 2022-12 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/14273 https://academic.oup.com/tas/article/6/4/txac154/6862071 2573-2102 https://doi.org/10.1093/tas/txac154 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf American Society of Animal Science Translational Animal Science 6 (4) : 1-9. (October 2022)
spellingShingle Buey
Ganado Bovino
Monensina
Virginiamicina
Feedlot
Sanidad Animal
Bullocks
Cattle
Monensin
Virginiamycin
Feedlots
Animal Health
Steers
Novillo
Ceconi, Irene
Viano, Sergio
Mendez, Daniel Gustavo
Gonzalez, Lucas
Davies, Patricio
Elizalde, Juan Carlos
Bressan, Elbio
Grandini, Danilo
Nagaraja, T.G.
Tedeschi, Luis O.
Combined use of monensin and virginiamycin to improve rumen and liver health and performance of feedlot-finished steers
title Combined use of monensin and virginiamycin to improve rumen and liver health and performance of feedlot-finished steers
title_full Combined use of monensin and virginiamycin to improve rumen and liver health and performance of feedlot-finished steers
title_fullStr Combined use of monensin and virginiamycin to improve rumen and liver health and performance of feedlot-finished steers
title_full_unstemmed Combined use of monensin and virginiamycin to improve rumen and liver health and performance of feedlot-finished steers
title_short Combined use of monensin and virginiamycin to improve rumen and liver health and performance of feedlot-finished steers
title_sort combined use of monensin and virginiamycin to improve rumen and liver health and performance of feedlot finished steers
topic Buey
Ganado Bovino
Monensina
Virginiamicina
Feedlot
Sanidad Animal
Bullocks
Cattle
Monensin
Virginiamycin
Feedlots
Animal Health
Steers
Novillo
url http://hdl.handle.net/20.500.12123/14273
https://academic.oup.com/tas/article/6/4/txac154/6862071
https://doi.org/10.1093/tas/txac154
work_keys_str_mv AT ceconiirene combineduseofmonensinandvirginiamycintoimproverumenandliverhealthandperformanceoffeedlotfinishedsteers
AT vianosergio combineduseofmonensinandvirginiamycintoimproverumenandliverhealthandperformanceoffeedlotfinishedsteers
AT mendezdanielgustavo combineduseofmonensinandvirginiamycintoimproverumenandliverhealthandperformanceoffeedlotfinishedsteers
AT gonzalezlucas combineduseofmonensinandvirginiamycintoimproverumenandliverhealthandperformanceoffeedlotfinishedsteers
AT daviespatricio combineduseofmonensinandvirginiamycintoimproverumenandliverhealthandperformanceoffeedlotfinishedsteers
AT elizaldejuancarlos combineduseofmonensinandvirginiamycintoimproverumenandliverhealthandperformanceoffeedlotfinishedsteers
AT bressanelbio combineduseofmonensinandvirginiamycintoimproverumenandliverhealthandperformanceoffeedlotfinishedsteers
AT grandinidanilo combineduseofmonensinandvirginiamycintoimproverumenandliverhealthandperformanceoffeedlotfinishedsteers
AT nagarajatg combineduseofmonensinandvirginiamycintoimproverumenandliverhealthandperformanceoffeedlotfinishedsteers
AT tedeschiluiso combineduseofmonensinandvirginiamycintoimproverumenandliverhealthandperformanceoffeedlotfinishedsteers