First report of Xanthomonas prunicola causing bacterial leaf streaks on wheat in Argentina

Since 2018, bacterial-like symptoms, such as leaf streaks were observed on wheat plants (Triticum aestivum L.) in Córdoba province in Argentina, with 1 to 5% of disease incidence. Samples of wheat stem and spike collected in a trial of varieties for summer/autumn sowing in the experimental field of...

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Main Authors: Martino, Julia Andrea, Fernandez, Franco Daniel, Pozzi, Elizabeth Alicia, Alberione, Enrique Javier, Bainotti, Carlos Tomas, Marquez, Nathalie, Tolocka, Patricia, Salines, Nicolas, Gomez, Dionisio Tomas, Donaire, Guillermo Manuel, Conci, Luis Rogelio, Alemandri, Vanina Maria
Format: info:ar-repo/semantics/artículo
Language:Inglés
Published: American Phytopathological Society 2022
Subjects:
Online Access:http://hdl.handle.net/20.500.12123/13392
https://apsjournals.apsnet.org/doi/10.1094/PDIS-04-22-0886-PDN
https://doi.org/10.1094/PDIS-04-22-0886-PDN
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author Martino, Julia Andrea
Fernandez, Franco Daniel
Pozzi, Elizabeth Alicia
Alberione, Enrique Javier
Bainotti, Carlos Tomas
Marquez, Nathalie
Tolocka, Patricia
Salines, Nicolas
Gomez, Dionisio Tomas
Donaire, Guillermo Manuel
Conci, Luis Rogelio
Alemandri, Vanina Maria
author_browse Alberione, Enrique Javier
Alemandri, Vanina Maria
Bainotti, Carlos Tomas
Conci, Luis Rogelio
Donaire, Guillermo Manuel
Fernandez, Franco Daniel
Gomez, Dionisio Tomas
Marquez, Nathalie
Martino, Julia Andrea
Pozzi, Elizabeth Alicia
Salines, Nicolas
Tolocka, Patricia
author_facet Martino, Julia Andrea
Fernandez, Franco Daniel
Pozzi, Elizabeth Alicia
Alberione, Enrique Javier
Bainotti, Carlos Tomas
Marquez, Nathalie
Tolocka, Patricia
Salines, Nicolas
Gomez, Dionisio Tomas
Donaire, Guillermo Manuel
Conci, Luis Rogelio
Alemandri, Vanina Maria
author_sort Martino, Julia Andrea
collection INTA Digital
description Since 2018, bacterial-like symptoms, such as leaf streaks were observed on wheat plants (Triticum aestivum L.) in Córdoba province in Argentina, with 1 to 5% of disease incidence. Samples of wheat stem and spike collected in a trial of varieties for summer/autumn sowing in the experimental field of the INTA Marcos Juárez were disinfected, washed and macerated in mortars with sterile distilled water and extracts were streaked on Luria-Bertani (LB) agar. After 48 h incubation at 28 °C, circular, mucoid, convex, and cream colonies were observed and pure cultures were transferred to LB medium for further identification tests. Biochemical tests corroborated the detection of a Gram-negative bacillus. Conventional PCR was performed using DNA isolate from pure cultures and general primers for various species of genera Xanthomonas (Maes 1993) and Pseudomonas (Mulet et al. 2010). An isolate (Arg-1), with cream colored colonies was positive using general primers for Xanthomonas sp (amplified fragment of 444 bp). A bacterial suspension containing 108 CFU mL−1 grown for 48 h on LB medium at 28 °C was injected into three-week-old leaves of wheat plants to fulfill Koch’s postulates. After 5 days, plants showed symptoms of chlorosis, streaks and then necrosis on the leaves. The bacteria were re-isolated from the inoculated plants, showing same symptoms observed in the original plants. Negative control plants, inoculated with sterile water remained without symptoms. The amplified 444 bp fragment described above was sequenced by the Sanger method (GenBank accession OM972662), as well as another 757 bp fragment amplified with universal primers that amplify the partial 16S rDNA gene (GenBank accession OM972661). Analyses of these sequences, as well as the protein profile of the isolate obtained by matrix assisted laser desorption/ionization time of-flight mass spectrometry (MALDI-TOF MS) Bruker Biotyper, allowed to identify only the genus Xanthomonas. With the purpose of determine the species status, the complete genome of isolate Arg-1 was sequenced using Oxford Nanopore Technologies (ONT). Total gDNA was isolate from pure cultures using a commercial kit (Wizard Genomic DNA Purification Kit, Promega). gDNA library was constructed using Ligation Sequencing Kit (SQK-LSK109) and sequenced using ONT platform on a MinION 1kb device. Raw basecalled sequences were filtered using Filtlong and assembled using Trycycler. The genome was assembled in a single contig comprising 5.410.641 bp with 4740 predicted CDSs and 63.9% GC content. Genome sequence was deposited in GenBank under accession number CP094827 and SRA data SRX14635308. Whole-genome Average Nucleotide Identity (ANI) analysis showed values of ~ 97% against the reference genomes of Xanthomonas prunicola (PHKX01.1, PHKV01.1 and PHKW01.1) and 100% in complete 16S rRNA gene sequences (1547 bp). These findings suggest that a new wheat pathogen within the genus Xanthomonas is present in Argentina, as well as was reported in Uruguay and USA (Clavijo et al. 2021). To our knowledge, this is the first report of X. prunicola affecting wheat in Argentina and the first complete genome registered for this specie. Accurate and specific diagnostics are required for the detection of X. prunicola in wheat crops to implement correct prevention and control strategies to this disease, avoiding the dissemination in lots where it has not yet been found.
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spelling INTA133922022-11-11T18:08:33Z First report of Xanthomonas prunicola causing bacterial leaf streaks on wheat in Argentina Martino, Julia Andrea Fernandez, Franco Daniel Pozzi, Elizabeth Alicia Alberione, Enrique Javier Bainotti, Carlos Tomas Marquez, Nathalie Tolocka, Patricia Salines, Nicolas Gomez, Dionisio Tomas Donaire, Guillermo Manuel Conci, Luis Rogelio Alemandri, Vanina Maria Argentina Triticum Aestivum Trigo Wheat Plant Diseases Enfermedades de las Plantas Xanthomonas Bacterial Leaf Streak of Wheat Pathogen Detection Xanthomonas Prunicola Since 2018, bacterial-like symptoms, such as leaf streaks were observed on wheat plants (Triticum aestivum L.) in Córdoba province in Argentina, with 1 to 5% of disease incidence. Samples of wheat stem and spike collected in a trial of varieties for summer/autumn sowing in the experimental field of the INTA Marcos Juárez were disinfected, washed and macerated in mortars with sterile distilled water and extracts were streaked on Luria-Bertani (LB) agar. After 48 h incubation at 28 °C, circular, mucoid, convex, and cream colonies were observed and pure cultures were transferred to LB medium for further identification tests. Biochemical tests corroborated the detection of a Gram-negative bacillus. Conventional PCR was performed using DNA isolate from pure cultures and general primers for various species of genera Xanthomonas (Maes 1993) and Pseudomonas (Mulet et al. 2010). An isolate (Arg-1), with cream colored colonies was positive using general primers for Xanthomonas sp (amplified fragment of 444 bp). A bacterial suspension containing 108 CFU mL−1 grown for 48 h on LB medium at 28 °C was injected into three-week-old leaves of wheat plants to fulfill Koch’s postulates. After 5 days, plants showed symptoms of chlorosis, streaks and then necrosis on the leaves. The bacteria were re-isolated from the inoculated plants, showing same symptoms observed in the original plants. Negative control plants, inoculated with sterile water remained without symptoms. The amplified 444 bp fragment described above was sequenced by the Sanger method (GenBank accession OM972662), as well as another 757 bp fragment amplified with universal primers that amplify the partial 16S rDNA gene (GenBank accession OM972661). Analyses of these sequences, as well as the protein profile of the isolate obtained by matrix assisted laser desorption/ionization time of-flight mass spectrometry (MALDI-TOF MS) Bruker Biotyper, allowed to identify only the genus Xanthomonas. With the purpose of determine the species status, the complete genome of isolate Arg-1 was sequenced using Oxford Nanopore Technologies (ONT). Total gDNA was isolate from pure cultures using a commercial kit (Wizard Genomic DNA Purification Kit, Promega). gDNA library was constructed using Ligation Sequencing Kit (SQK-LSK109) and sequenced using ONT platform on a MinION 1kb device. Raw basecalled sequences were filtered using Filtlong and assembled using Trycycler. The genome was assembled in a single contig comprising 5.410.641 bp with 4740 predicted CDSs and 63.9% GC content. Genome sequence was deposited in GenBank under accession number CP094827 and SRA data SRX14635308. Whole-genome Average Nucleotide Identity (ANI) analysis showed values of ~ 97% against the reference genomes of Xanthomonas prunicola (PHKX01.1, PHKV01.1 and PHKW01.1) and 100% in complete 16S rRNA gene sequences (1547 bp). These findings suggest that a new wheat pathogen within the genus Xanthomonas is present in Argentina, as well as was reported in Uruguay and USA (Clavijo et al. 2021). To our knowledge, this is the first report of X. prunicola affecting wheat in Argentina and the first complete genome registered for this specie. Accurate and specific diagnostics are required for the detection of X. prunicola in wheat crops to implement correct prevention and control strategies to this disease, avoiding the dissemination in lots where it has not yet been found. Instituto de Patología Vegetal Fil: Martino, Julia Andrea. Fondo para la Investigación Científica y Tecnológica (FONCYT); Argentina Fil: Martino, Julia Andrea. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; Argentina Fil: Fernandez, Franco Daniel. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; Argentina Fil: Fernandez, Franco Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Fitopatología y Modelización Agrícola (UFyMA); Argentina Fil: Pozzi, Elizabeth Alicia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Marcos Juárez; Argentina Fil: Alberione, Enrique Javier. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Marcos Juárez; Argentina Fil: Bainotti, Carlos Tomas. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Marcos Juárez; Argentina Fil: Marquez, Nathalie. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; Argentina Fil: Marquez, Nathalie. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Fitopatología y Modelización Agrícola (UFyMA); Argentina Fil: Tolocka, Patricia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; Argentina Fil: Tolocka, Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Fitopatología y Modelización Agrícola (UFyMA); Argentina Fil: Salines, Nicolas. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Marcos Juárez; Argentina Fil: Gomez, Dionisio Tomas. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Marcos Juárez; Argentina Fil: Donaire, Guillermo Manuel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Marcos Juárez; Argentina Fil: Conci, Luis Rogelio. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; Argentina Fil: Conci, Luis Rogelio. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Fitopatología y Modelización Agrícola (UFyMA); Argentina Fil: Alemandri, Vanina Maria. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; Argentina Fil: Alemandri, Vanina Maria. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Fitopatología y Modelización Agrícola (UFyMA); Argentina 2022-11-11T17:59:33Z 2022-11-11T17:59:33Z 2022-06-13 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/13392 https://apsjournals.apsnet.org/doi/10.1094/PDIS-04-22-0886-PDN 0191-2917 https://doi.org/10.1094/PDIS-04-22-0886-PDN eng info:eu-repograntAgreement/INTA/2019-PD-E4-I090-001/2019-PD-E4-I090-001/AR./Análisis de patosistemas en cultivos agrícolas y especies forestales. Caracterización de sus componentes info:eu-repograntAgreement/INTA/2019-PE-E6-I126-001/2019-PE-E6-I126-001/AR./Mejoramiento genético de trigo pan (Triticum aestivum L.) y trigo candeal (Triticum turgidum ssp. durum Desf.) info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf American Phytopathological Society Plant Disease (Published Online:13 Jun 2022)
spellingShingle Argentina
Triticum Aestivum
Trigo
Wheat
Plant Diseases
Enfermedades de las Plantas
Xanthomonas
Bacterial Leaf Streak of Wheat
Pathogen Detection
Xanthomonas Prunicola
Martino, Julia Andrea
Fernandez, Franco Daniel
Pozzi, Elizabeth Alicia
Alberione, Enrique Javier
Bainotti, Carlos Tomas
Marquez, Nathalie
Tolocka, Patricia
Salines, Nicolas
Gomez, Dionisio Tomas
Donaire, Guillermo Manuel
Conci, Luis Rogelio
Alemandri, Vanina Maria
First report of Xanthomonas prunicola causing bacterial leaf streaks on wheat in Argentina
title First report of Xanthomonas prunicola causing bacterial leaf streaks on wheat in Argentina
title_full First report of Xanthomonas prunicola causing bacterial leaf streaks on wheat in Argentina
title_fullStr First report of Xanthomonas prunicola causing bacterial leaf streaks on wheat in Argentina
title_full_unstemmed First report of Xanthomonas prunicola causing bacterial leaf streaks on wheat in Argentina
title_short First report of Xanthomonas prunicola causing bacterial leaf streaks on wheat in Argentina
title_sort first report of xanthomonas prunicola causing bacterial leaf streaks on wheat in argentina
topic Argentina
Triticum Aestivum
Trigo
Wheat
Plant Diseases
Enfermedades de las Plantas
Xanthomonas
Bacterial Leaf Streak of Wheat
Pathogen Detection
Xanthomonas Prunicola
url http://hdl.handle.net/20.500.12123/13392
https://apsjournals.apsnet.org/doi/10.1094/PDIS-04-22-0886-PDN
https://doi.org/10.1094/PDIS-04-22-0886-PDN
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