Morphometric study of encephalic lesions in aborted bovine fetuses naturally infected by two subpopulations of Neospora caninum
Neospora caninum is a major reproductive disease in cattle worldwide. In the Argentinian Humid Pampa, the seroprevalence, incidence of abortions, and economic losses due to neosporosis are considerably higher in dairy than in beef cattle. Despite this, we recently demonstrated that N. caninum subpop...
| Autores principales: | , , , , , , , |
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| Formato: | Artículo |
| Lenguaje: | Inglés |
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Springer
2022
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12123/13346 https://link.springer.com/article/10.1007/s00436-021-07248-y https://doi.org/10.1007/s00436-021-07248-y |
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| author | Dorsch, Matías Moore, Prando Dadin Regidor Cerrillo, Javier Scioli, Maria Valeria Morrell, Eleonora Lidia Canton, German Jose Ortega Mora, Luis Hecker, Yanina |
| author_browse | Canton, German Jose Dorsch, Matías Hecker, Yanina Moore, Prando Dadin Morrell, Eleonora Lidia Ortega Mora, Luis Regidor Cerrillo, Javier Scioli, Maria Valeria |
| author_facet | Dorsch, Matías Moore, Prando Dadin Regidor Cerrillo, Javier Scioli, Maria Valeria Morrell, Eleonora Lidia Canton, German Jose Ortega Mora, Luis Hecker, Yanina |
| author_sort | Dorsch, Matías |
| collection | INTA Digital |
| description | Neospora caninum is a major reproductive disease in cattle worldwide. In the Argentinian Humid Pampa, the seroprevalence, incidence of abortions, and economic losses due to neosporosis are considerably higher in dairy than in beef cattle. Despite this, we recently demonstrated that N. caninum subpopulations are indistinctly distributed in both dairy and beef production systems. The association between genotypic characteristics defined by microsatellite analysis and the virulence of the different strains—particularly with regard to the severity and extension of histological lesions—is largely unknown. Herein, we used a morphometric approach to analyze encephalic lesions in 62 bovine fetuses spontaneously infected by N. caninum. Morphometric parameters (average size of focal lesions, number of foci/cm2 and the percentage of the section affected by lesions) were compared according to the N. caninum subpopulations found in our previous microsatellite genotyping analysis, animal biotype (beef versus dairy), and fetal age (second stage of gestation versus third stage). The average size of the lesions differed significantly among fetuses with different gestational ages; however, no significant differences among animal biotypes or genotypic patterns were found. Further research into the genetic, molecular, and husbandry factors that could account for this greater impact in Argentinian dairy herds is needed. |
| format | Artículo |
| id | INTA13346 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | Springer |
| publisherStr | Springer |
| record_format | dspace |
| spelling | INTA133462022-11-08T17:20:33Z Morphometric study of encephalic lesions in aborted bovine fetuses naturally infected by two subpopulations of Neospora caninum Dorsch, Matías Moore, Prando Dadin Regidor Cerrillo, Javier Scioli, Maria Valeria Morrell, Eleonora Lidia Canton, German Jose Ortega Mora, Luis Hecker, Yanina Neospora Caninum Fetos Ganado Bovino Aborto Cerebro Lesiones Foetus Cattle Abortion Brain Lesions Neospora caninum is a major reproductive disease in cattle worldwide. In the Argentinian Humid Pampa, the seroprevalence, incidence of abortions, and economic losses due to neosporosis are considerably higher in dairy than in beef cattle. Despite this, we recently demonstrated that N. caninum subpopulations are indistinctly distributed in both dairy and beef production systems. The association between genotypic characteristics defined by microsatellite analysis and the virulence of the different strains—particularly with regard to the severity and extension of histological lesions—is largely unknown. Herein, we used a morphometric approach to analyze encephalic lesions in 62 bovine fetuses spontaneously infected by N. caninum. Morphometric parameters (average size of focal lesions, number of foci/cm2 and the percentage of the section affected by lesions) were compared according to the N. caninum subpopulations found in our previous microsatellite genotyping analysis, animal biotype (beef versus dairy), and fetal age (second stage of gestation versus third stage). The average size of the lesions differed significantly among fetuses with different gestational ages; however, no significant differences among animal biotypes or genotypic patterns were found. Further research into the genetic, molecular, and husbandry factors that could account for this greater impact in Argentinian dairy herds is needed. EEA Balcarce Fil: Dorsch, Matias A. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina. Fil: Dorsch, Matias A. Instituto Nacional de Investigación Agropecuaria. La Estanzuela; Uruguay. Fil: Moore, Dadín Prando. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina. Fil: Moore, Dadín Prando. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Fil: Regidor Cerrillo, Javier. Universidad Complutense de Madrid. Facultad de Veterinaria; España. Fil: Scioli, María Valeria. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Fil: Morrell, Eleonora Lidia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Fil: Cantón, Germán José. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Fil: Ortega Mora, Luis M. Universidad Complutense de Madrid. Facultad de Veterinaria; España. Fil: Hecker, Yanina. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. 2022-11-08T17:11:05Z 2022-11-08T17:11:05Z 2021-08 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/13346 https://link.springer.com/article/10.1007/s00436-021-07248-y 1432-1955 (online) 0932-0113(print) https://doi.org/10.1007/s00436-021-07248-y eng info:eu-repograntAgreement/INTA/2019-PD-E5-I102-001/2019-PD-E5-I102-001/AR./Desarrollo de vacunas y tecnologías para mejorar las estrategias profilácticas y terapéuticas de las enfermedades que afectan la producción animal y la salud pública info:eu-repograntAgreement/INTA/2019-PD-E5-I103-001/2019-PD-E5-I103-001/AR./Desarrollo de tecnologías diagnósticas y estudios epidemiológicos para el control de enfermedades que afectan la producción animal y la salud pública info:eu-repograntAgreement/INTA/2019-PD-E5-I105-001/2019-PD-E5-I105-001/AR./Patógenos animales: su interacción con el hospedador y el medio ambiente. Impacto en productividad, ecosistemas, sanidad animal y salud pública en el marco “Una Salud” info:eu-repo/semantics/restrictedAccess application/pdf Springer Parasitology Research 120 : 2995–3000 (2021) |
| spellingShingle | Neospora Caninum Fetos Ganado Bovino Aborto Cerebro Lesiones Foetus Cattle Abortion Brain Lesions Dorsch, Matías Moore, Prando Dadin Regidor Cerrillo, Javier Scioli, Maria Valeria Morrell, Eleonora Lidia Canton, German Jose Ortega Mora, Luis Hecker, Yanina Morphometric study of encephalic lesions in aborted bovine fetuses naturally infected by two subpopulations of Neospora caninum |
| title | Morphometric study of encephalic lesions in aborted bovine fetuses naturally infected by two subpopulations of Neospora caninum |
| title_full | Morphometric study of encephalic lesions in aborted bovine fetuses naturally infected by two subpopulations of Neospora caninum |
| title_fullStr | Morphometric study of encephalic lesions in aborted bovine fetuses naturally infected by two subpopulations of Neospora caninum |
| title_full_unstemmed | Morphometric study of encephalic lesions in aborted bovine fetuses naturally infected by two subpopulations of Neospora caninum |
| title_short | Morphometric study of encephalic lesions in aborted bovine fetuses naturally infected by two subpopulations of Neospora caninum |
| title_sort | morphometric study of encephalic lesions in aborted bovine fetuses naturally infected by two subpopulations of neospora caninum |
| topic | Neospora Caninum Fetos Ganado Bovino Aborto Cerebro Lesiones Foetus Cattle Abortion Brain Lesions |
| url | http://hdl.handle.net/20.500.12123/13346 https://link.springer.com/article/10.1007/s00436-021-07248-y https://doi.org/10.1007/s00436-021-07248-y |
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