Cow management modulates gene expression in the mammary gland, a possible epigenetics role
Epigenetics, the study of the change in gene expression that occurs without alteration in DNA sequences, leads to modifications that can be passed on by mitosis. It has been known for many years that cow management during lactation affects milk production. Now it is clear that some factors influence...
| Autores principales: | , |
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| Formato: | info:ar-repo/semantics/artículo |
| Lenguaje: | Inglés |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12123/1282 http://www.sciencedirect.com/science/article/pii/S1871141315001419 https://doi.org/10.1016/j.livsci.2015.03.013 |
| _version_ | 1855034777816530944 |
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| author | Gigli, Isabel Maizon, Daniel Omar |
| author_browse | Gigli, Isabel Maizon, Daniel Omar |
| author_facet | Gigli, Isabel Maizon, Daniel Omar |
| author_sort | Gigli, Isabel |
| collection | INTA Digital |
| description | Epigenetics, the study of the change in gene expression that occurs without alteration in DNA sequences, leads to modifications that can be passed on by mitosis. It has been known for many years that cow management during lactation affects milk production. Now it is clear that some factors influence milk production even before the onset of lactation (during the dry period). In the last decade, a greater understanding of the molecular events that occur in the mammary epithelial cells provided an explanation for these changes. Gene expression in the mammary gland shows a temporal–spatial regulation. This is achieved by different regulatory layers of gene expression involving, for example, chromatin condensation and the combinations of several hormones and transcription factors. The goal of this review is to bring together an update of studies on gene expression in the mammary gland, highlighting the possible influence of cow management on epigenetic mechanisms. The impacts of milking frequency, mastitis, photoperiod and heat stress on gene expression and their effects on milk production were discussed. Understanding how the mammary gland responds to external factors will help to design better strategies and technologies to enhance milk production. |
| format | info:ar-repo/semantics/artículo |
| id | INTA1282 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| record_format | dspace |
| spelling | INTA12822018-06-28T12:04:34Z Cow management modulates gene expression in the mammary gland, a possible epigenetics role Gigli, Isabel Maizon, Daniel Omar Ganado Bovino Cattle Cows Mammary Glands Heat Stress Milking Photoperiodicity Vaca Mastitis Glándulas Mamarias Estrés Térmico Ordeño Fotoperiodismo Genes Epigenética Epigenetics Frecuencia de Ordeño Milking Frequency Epigenetics, the study of the change in gene expression that occurs without alteration in DNA sequences, leads to modifications that can be passed on by mitosis. It has been known for many years that cow management during lactation affects milk production. Now it is clear that some factors influence milk production even before the onset of lactation (during the dry period). In the last decade, a greater understanding of the molecular events that occur in the mammary epithelial cells provided an explanation for these changes. Gene expression in the mammary gland shows a temporal–spatial regulation. This is achieved by different regulatory layers of gene expression involving, for example, chromatin condensation and the combinations of several hormones and transcription factors. The goal of this review is to bring together an update of studies on gene expression in the mammary gland, highlighting the possible influence of cow management on epigenetic mechanisms. The impacts of milking frequency, mastitis, photoperiod and heat stress on gene expression and their effects on milk production were discussed. Understanding how the mammary gland responds to external factors will help to design better strategies and technologies to enhance milk production. Fil: Gigli, Isabel. Universidad Nacional de La Pampa. Facultad de Agronomía; Argentina Fil: Maizon, Daniel Omar Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguill “Ing. Agr. Guillermo Covas”; Argentina 2017-09-21T13:42:21Z 2017-09-21T13:42:21Z 2015 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/1282 http://www.sciencedirect.com/science/article/pii/S1871141315001419 1871-1413 https://doi.org/10.1016/j.livsci.2015.03.013 eng info:eu-repo/semantics/restrictedAccess application/pdf Livestock science 176 : 181-187. (June 2015) |
| spellingShingle | Ganado Bovino Cattle Cows Mammary Glands Heat Stress Milking Photoperiodicity Vaca Mastitis Glándulas Mamarias Estrés Térmico Ordeño Fotoperiodismo Genes Epigenética Epigenetics Frecuencia de Ordeño Milking Frequency Gigli, Isabel Maizon, Daniel Omar Cow management modulates gene expression in the mammary gland, a possible epigenetics role |
| title | Cow management modulates gene expression in the mammary gland, a possible epigenetics role |
| title_full | Cow management modulates gene expression in the mammary gland, a possible epigenetics role |
| title_fullStr | Cow management modulates gene expression in the mammary gland, a possible epigenetics role |
| title_full_unstemmed | Cow management modulates gene expression in the mammary gland, a possible epigenetics role |
| title_short | Cow management modulates gene expression in the mammary gland, a possible epigenetics role |
| title_sort | cow management modulates gene expression in the mammary gland a possible epigenetics role |
| topic | Ganado Bovino Cattle Cows Mammary Glands Heat Stress Milking Photoperiodicity Vaca Mastitis Glándulas Mamarias Estrés Térmico Ordeño Fotoperiodismo Genes Epigenética Epigenetics Frecuencia de Ordeño Milking Frequency |
| url | http://hdl.handle.net/20.500.12123/1282 http://www.sciencedirect.com/science/article/pii/S1871141315001419 https://doi.org/10.1016/j.livsci.2015.03.013 |
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