Reactivation and foetal infection in pregnant heifers infected with neospora caninum live tachyzoites at prepubertal age
Neospora caninum is recognised for causing cattle abortion, provoking severe economic losses in the livestock industry worldwide. The aim of the present study was to evaluate the reactivation and foetal infection in pregnant heifers inoculated with live N. caninum tachyzoites before puberty. A total...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Artículo |
| Lenguaje: | Inglés |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12123/12494 https://www.mdpi.com/2076-393X/10/8/1175 https://doi.org/10.3390/vaccines10081175 |
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| author | Hecker, Yanina Burucúa, Mercedes María Fiorani, Franco Maldonado Rivera, Jaime Cirone, Karina Mariela Dorsch, Matías Cheuquepan Valenzuela, Felipe Campero, Lucia Maria Canton, German Jose Marín, Maia Ortega Mora, Luis Moore, Prando Dadin |
| author_browse | Burucúa, Mercedes María Campero, Lucia Maria Canton, German Jose Cheuquepan Valenzuela, Felipe Cirone, Karina Mariela Dorsch, Matías Fiorani, Franco Hecker, Yanina Maldonado Rivera, Jaime Marín, Maia Moore, Prando Dadin Ortega Mora, Luis |
| author_facet | Hecker, Yanina Burucúa, Mercedes María Fiorani, Franco Maldonado Rivera, Jaime Cirone, Karina Mariela Dorsch, Matías Cheuquepan Valenzuela, Felipe Campero, Lucia Maria Canton, German Jose Marín, Maia Ortega Mora, Luis Moore, Prando Dadin |
| author_sort | Hecker, Yanina |
| collection | INTA Digital |
| description | Neospora caninum is recognised for causing cattle abortion, provoking severe economic losses in the livestock industry worldwide. The aim of the present study was to evaluate the reactivation and foetal infection in pregnant heifers inoculated with live N. caninum tachyzoites before puberty. A total of 15 30-month-old pregnant heifers were allocated into four groups: animals inoculated with live tachyzoites of NC-Argentina LP1 isolate before puberty and challenged with live tachyzoites of NC-1 strain at 210 days of gestation (DG) (Group A); animals mock inoculated before puberty and challenged with NC-1 strain at 210 DG (Group B), animals inoculated before puberty but not subsequently challenged (Group C); and noninfected and nonchallenged animals (Group D). The results of this study showed that 100% of animals infected before puberty (Groups A and C) suffered reactivation of the infection at the seventh month of gestation. In addition, in three and two calves from Groups A and C, respectively, congenital infection was confirmed. Interestingly, we provide evidence that the use of live N. caninum tachyzoites in young animals as a strategy to induce protection is neither safe nor effective. |
| format | Artículo |
| id | INTA12494 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI |
| publisherStr | MDPI |
| record_format | dspace |
| spelling | INTA124942022-08-04T12:02:36Z Reactivation and foetal infection in pregnant heifers infected with neospora caninum live tachyzoites at prepubertal age Hecker, Yanina Burucúa, Mercedes María Fiorani, Franco Maldonado Rivera, Jaime Cirone, Karina Mariela Dorsch, Matías Cheuquepan Valenzuela, Felipe Campero, Lucia Maria Canton, German Jose Marín, Maia Ortega Mora, Luis Moore, Prando Dadin Ganado Bovino Neospora Caninum Inoculación Parásitos Infección Experimental Seguridad Eficacia Cattle Inoculation Parasites Experimental Infection Safety Efficiency Neospora caninum is recognised for causing cattle abortion, provoking severe economic losses in the livestock industry worldwide. The aim of the present study was to evaluate the reactivation and foetal infection in pregnant heifers inoculated with live N. caninum tachyzoites before puberty. A total of 15 30-month-old pregnant heifers were allocated into four groups: animals inoculated with live tachyzoites of NC-Argentina LP1 isolate before puberty and challenged with live tachyzoites of NC-1 strain at 210 days of gestation (DG) (Group A); animals mock inoculated before puberty and challenged with NC-1 strain at 210 DG (Group B), animals inoculated before puberty but not subsequently challenged (Group C); and noninfected and nonchallenged animals (Group D). The results of this study showed that 100% of animals infected before puberty (Groups A and C) suffered reactivation of the infection at the seventh month of gestation. In addition, in three and two calves from Groups A and C, respectively, congenital infection was confirmed. Interestingly, we provide evidence that the use of live N. caninum tachyzoites in young animals as a strategy to induce protection is neither safe nor effective. EEA Balcarce Fil: Hecker, Yanina Paola. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Fil: Burucúa, Mercedes. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Fil: Fiorani, Franco. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Fil: Fiorani, Franco. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina. Fil: Maldonado Rivera, Jaime. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina. Fil: Maldonado Rivera, Jaime. Universidad de Cuenca. Facultad de Ciencias Agropecuarias; Ecuador. Fil: Cirone, Karina. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Fil: Cirone, Karina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina. Fil: Dorsch, Matías. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina. Fil: Dorsch, Matías. Instituto Nacional de Investigación Agropecuaria (INIA). Estación Experimental La Estanzuela; Uruguay Fil: Cheuquepán Valenzuela, Felipe. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Fil: Campero, Lucía. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Fil: Cantón, Germán José. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Fil: Marín, Maia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Fil: Ortega Mora, Luis. Universidad Complutense de Madrid. Facultad de Ciencias Veterinarias; España Fil: Moore, Dadin Prando. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. 2022-08-04T11:39:47Z 2022-08-04T11:39:47Z 2022-07-25 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/12494 https://www.mdpi.com/2076-393X/10/8/1175 2076-393X https://doi.org/10.3390/vaccines10081175 eng info:eu-repograntAgreement/INTA/PNSA-1115053/AR./Biotecnologías reproductivas y desarrollo de metodologías de diagnóstico, control y prevención de las enfermedades infecciosas y parasitarias que afectan la concepción, gestación y período neonatal en especies de interés zootécnico. info:eu-repograntAgreement/INTA/2019-PD-E5-I102-001/2019-PD-E5-I102-001/AR./Desarrollo de vacunas y tecnologías para mejorar las estrategias profilácticas y terapéuticas de las enfermedades que afectan la producción animal y la salud pública info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf MDPI Vaccines 10 (8) : 1175 (2022) |
| spellingShingle | Ganado Bovino Neospora Caninum Inoculación Parásitos Infección Experimental Seguridad Eficacia Cattle Inoculation Parasites Experimental Infection Safety Efficiency Hecker, Yanina Burucúa, Mercedes María Fiorani, Franco Maldonado Rivera, Jaime Cirone, Karina Mariela Dorsch, Matías Cheuquepan Valenzuela, Felipe Campero, Lucia Maria Canton, German Jose Marín, Maia Ortega Mora, Luis Moore, Prando Dadin Reactivation and foetal infection in pregnant heifers infected with neospora caninum live tachyzoites at prepubertal age |
| title | Reactivation and foetal infection in pregnant heifers infected with neospora caninum live tachyzoites at prepubertal age |
| title_full | Reactivation and foetal infection in pregnant heifers infected with neospora caninum live tachyzoites at prepubertal age |
| title_fullStr | Reactivation and foetal infection in pregnant heifers infected with neospora caninum live tachyzoites at prepubertal age |
| title_full_unstemmed | Reactivation and foetal infection in pregnant heifers infected with neospora caninum live tachyzoites at prepubertal age |
| title_short | Reactivation and foetal infection in pregnant heifers infected with neospora caninum live tachyzoites at prepubertal age |
| title_sort | reactivation and foetal infection in pregnant heifers infected with neospora caninum live tachyzoites at prepubertal age |
| topic | Ganado Bovino Neospora Caninum Inoculación Parásitos Infección Experimental Seguridad Eficacia Cattle Inoculation Parasites Experimental Infection Safety Efficiency |
| url | http://hdl.handle.net/20.500.12123/12494 https://www.mdpi.com/2076-393X/10/8/1175 https://doi.org/10.3390/vaccines10081175 |
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